Release of dibenzoyl peroxide from polymethyl methacrylate denture base resins: An in vitro evaluation

Boeckler, Arne F.; Morton, Dean; Poser, S.; Dette, Karl-Ernst

doi:10.1016/j.dental.2008.03.019

Cited by 38 publications

(33 citation statements)

References 17 publications

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“…The high decrease of RM content due to ethanol treatment compared to water may partially explain the greatest impact of the novel postpolymerization treatment on materials toxicity. Moreover, it is known that in vitro cytotoxicity might not only be the result of the leaching RM but also other components such as additives, byproducts, impurities, and decomposed products [11, 18] with enhanced solubility in ethanol-water solutions. …”

Section: Discussionmentioning

confidence: 99%

“…Bettencourt et al [20] showed that ethanol increases the RM leaching from the polymer matrix of acrylic bone cements used in joint arthroplasty. Other studies found that immersion in pure ethanol (99.5%) promoted a reduction of the residual compounds content on acrylic polymers used in dentistry as denture base resins [18] and temporary restorative resins [19]. Ethanol molecules penetrate the material matrix and expand the space between polymer chains into which insoluble substances may diffuse [18].…”

Section: Introductionmentioning

confidence: 99%

“…Other studies found that immersion in pure ethanol (99.5%) promoted a reduction of the residual compounds content on acrylic polymers used in dentistry as denture base resins [18] and temporary restorative resins [19]. Ethanol molecules penetrate the material matrix and expand the space between polymer chains into which insoluble substances may diffuse [18]. Ethanol also accelerates water sorption to the polymer matrix, promoting the RM diffusion from the polymer [21].…”

Section: Introductionmentioning

confidence: 99%

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Ethanol Postpolymerization Treatment for Improving the Biocompatibility of Acrylic Reline Resins

Neves

Lopes

Ferrão

et al. 2013

BioMed Research International

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Objective. To evaluate the effect of postpolymerization treatment based on ethanol-aqueous solutions on the residual monomer (RM) content, flexural strength, microhardness, and cytotoxicity of hard chairside reline resins (Kooliner, Ufi Gel Hard). Methods. After polymerization, specimens were immersed in water, 20%, 50%, or 70% ethanol solutions at 23°C or 55°C for 10 minutes. Controls were left untreated. HPLC was used for the determination of RM content. Specimens were submitted to Vickers microhardness and 3-point loading flexural strength tests. Cytotoxicity of resin eluates was determined on human fibroblasts by assessing cellular mitochondrial function and lactate dehydrogenase release. Results. Higher concentrations of ethanol promoted lower RM content at 55°C in both materials. The mechanical properties were maintained after 50% and 20% ethanol treatments in Kooliner and Ufi Gel Hard, respectively. Specimens submitted to those treatments showed significant reduction on cytotoxicity compared to immersion in hot water, the treatment of choice in the recent literature. Significance. Immersion of relined dentures in specific ethanol solutions at 55°C for 10 minutes can be considered an effective postpolymerization treatment contributing to increase materials biocompatibility. The proposed protocol is expeditious and easy to achieve with simple equipment in a dental office.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Ethanol Postpolymerization Treatment for Improving the Biocompatibility of Acrylic Reline Resins

Neves

Lopes

Ferrão

et al. 2013

BioMed Research International

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“…It has been shown that RBCs properties improve as the DC obtained during photo-polymerization increases (2). An inadequate DC may results in reduced hardness, decreased dynamic elastic modulus, reduced flexural and fractural strengths, decreased biocompatibility due to the leach of unreacted monomers (3), and increased wear and breakdown at the margins of the resin restoration (4)(5)(6). Therefore, DC plays an important role in determining the ultimate success of restorations (4)(5)(6).…”

Section: Introductionmentioning

confidence: 99%

Curing Effectiveness of Single-Peak and Multi-Peak Led Light Curing Units on Tpo-Containing Resin Composites With Different Chromatic Characteristics

Conte

Panetta

Mancini

et al. 2017

ORL

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SUMMARYThis study evaluated the surface microhardness of Lucirin-TPO (TPO) containing resin based composite (RBC) cured with three light-emitting diode (LED) light curing units (LCUs) (two single-peak LED and one multi-peak LED), and two different energy density (ED) (8 J/cm 2 and 16 J/cm 2 ). Ninety specimens (8 mm wide and 2 mm thick) (n=5), were prepared with three different shades: translucent (T), A2 dentin (A2d), and A4 dentin (A4d). Specimens were subjected to micro-hardness Vickers measurements (Vickers Hardness Number, VHN) on both top and bottom surfaces. Hardness ratio (rHV) was also calculated. Data were analyzed using multifactorial ANOVA and Bonferroni tests (<=0.05). Results indicated that higher ED performed better than lower ED. Multi-peak LED achieved higher VHNs and rHV than single-peak LED when curing a TPO-containing RBC. A4d invariably achieved lower rHV and VHN than T and A2d. Single-peak LED achieved comparable VHNs and rHVs with multi-peak LED only curing A2d and T shades with 16J/cm 2 .

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“…The level of residual monomer is related to the DC and polymerisation which can be achieved using chemical activators in autopolymerising acrylic resin 13,14) . Consequently, DC is a critical parameter that influences the biocompatibility and the mechanical and physical properties of dental polymers 12,15) and assessing the DC is a valuable tool for evaluating the mechanical properties of a polymer and its clinical performance.…”

Section: Introductionmentioning

confidence: 99%

Impregnation with antimicrobials has an impact on degree of conversion and colour stability of acrylic liner

et al. 2012

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This study investigated the impact of impregnation of a poly(ethyl methacrylate) /tetrahydrofurfuryl methacrylate (PEM/THFM) polymer with chlorhexidine or fluconazole on the degree of conversion (DC) and colour stability (ΔE). The DC of uncured (0 h) and cured (24 h) samples was analysed by Fourier transform infrared spectroscopy (FTIR) and colour stability was analysed colorimetrically. The DC percentage of the control samples was significantly greater than those containing chlorhexidine and fluconazole (p≤0.05). The control discs exhibited only slight colour change compared to the impregnated discs which showed marked colour change (p≤0.05). A strong negative correlation between the extent of colour change and the degree of conversion was detected (r=0.97). The DC and colour stability were influenced by the addition of chlorhexidine or fluconazole. However, the final values were comparable to other commonly used acrylic liners and within acceptable ranges. PEM/THFM can be considered as a biocompatible drug delivery system.

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Release of dibenzoyl peroxide from polymethyl methacrylate denture base resins: An in vitro evaluation

Cited by 38 publications

References 17 publications

Ethanol Postpolymerization Treatment for Improving the Biocompatibility of Acrylic Reline Resins

Ethanol Postpolymerization Treatment for Improving the Biocompatibility of Acrylic Reline Resins

Curing Effectiveness of Single-Peak and Multi-Peak Led Light Curing Units on Tpo-Containing Resin Composites With Different Chromatic Characteristics

Impregnation with antimicrobials has an impact on degree of conversion and colour stability of acrylic liner

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