Relaxin in porcine corpora lutea during pregnancy and after hysterectomy

Abstract

The APS Journal Legacy Content is the corpus of 100 years of historical scientific research from the American Physiological Society research journals. This package goes back to the first issue of each of the APS journals including the American Journal of Physiology, first published in 1898. The full text scanned images of the printed pages are easily searchable. Downloads quickly in PDF format.

Identification of relaxins in porcine follicular fluid and in the ovary of the immature sow

“…In the pig, the corpus luteum of pregnancy has been considered to be a rich source of relaxin, although Anderson et al (1973) found that relaxin was produced by the maintained corpus luteum of the hysterectomized sow. During pregnancy the corpus luteum must reach a certain age before synthesis and/or secretion of relaxin can take place (Sherwood, Martin, Chang & Dziuk, 1977).…”

“…Many investigators considered that this hormone was solely a product of the corpus luteum (Belt et al, 1971;Anderson, Ford, Melampy & Cox, 1973), but isolation studies of pregnant sow ovaries have indicated that relaxin can exhibit microheterogeneity (Sherwood & O'Byrne, 1974). To date, two structures have been proposed for porcine relaxin with a molecular weight of approxi¬ mately 6300 (Schwabe & McDonald, 1976;Schwabe, McDonald & Steinetz, 1977;James, Niall, Kwok & Bryant-Greenwood, 1977).…”

Endocrinology of parturition in the pig

“…2) starting to appear around 28 days of pregnancy. Only near term does relaxin reach maximal values to disappear again shortly prior to expulsion of the fetus (Anderson et al, 1973;Sherwood et al, 1975). Relaxin secretion is readily increased by prostaglandins (Sherwood et al, 1976).…”

Synergistic effects of insulin-like growth factor I and gonadotrophins on relaxin and progesterone secretion by ageing corpora lutea of pigs

“…Relaxin and progesterone are produced by corpora lutea of pigs during pregnancy and after hysterectomy (Belt et al, 1970(Belt et al, , 1971Anderson et al, 1973Anderson et al, , 1983. The corpora lutea from oestrous cycles of about 21 days secrete progesterone and small amounts of relaxin (Masuda et al, 1967;Anderson et al, 1973;.…”

“…The corpora lutea from oestrous cycles of about 21 days secrete progesterone and small amounts of relaxin (Masuda et al, 1967;Anderson et al, 1973;. During a normal pregnancy of 114 days, circulating progesterone concentrations peak by day 8 and remain high until they decrease just before parturition.…”