Relationships between implant stability, image‐based measures and nitric oxide levels

Abstract

For monitoring of dental implants, practitioners seem to use simultaneously a variety of image-based and laboratory measurements. This longitudinal study was conducted to analyse the possible relationships between nitric oxide (NO) content of peri-implant sulcus fluid (PISF), marginal bone levels and implant stability in terms of resonance frequency analysis (RFA) at immediately (IL) and conventionally (CL) loaded mandibular molar dental implants from the same individuals. Dental implants were placed in 10 patients who had first molar loss bilaterally in the mandibular area. One site of the patient was determined as IL and the other site was CL. PISF samples, marginal bone level and RFA were taken for all dental implants during a 12-month follow-up period. For both types of loading, there were no significant changes at implant stability (ISQ) and PISF volume during the whole study period. The lowest total nitrite levels were observed at the end of 12 months. Marginal bone gain of 0.22 and 0.09 mm was noticed between 6 and 12 months in IL and CL groups, respectively. During the study period, negative correlation was noted between radiographic bone level and ISQ at both IL and CL sites; however, this correlation reached a significant level only at 6 months in CL implant group (P = 0.015). Although not significant, marginal bone loss seems to have a negative relationship with the implant stability values regardless of the mode of loading. NO metabolism around IL and CL dental implants may not demonstrate a significantly different pattern.

Analysis of Cathepsin‐K Activity at Tooth and Dental Implant Sites and the Potential of This Enzyme in Reflecting Alveolar Bone Loss

“…Studies analyzing the levels of different ingredients in GCF/PISF used activity level instead of concentration because it is shown that a number of factors affect vGCF/vPISF 35‐40 and because activity level of a given ingredient gives more reliable, sensitive, and accurate information about the investigated enzyme 36‐40 . In the present study, the highest total cathepsin‐K activity levels are detected in natural teeth and dental implant subgroups presented with alveolar bone loss.…”

Initial Stability of Two Dental Implant Systems: Influence of Buccolingual Width and Probe Orientation on Resonance Frequency Measurements

“…ISQ values recorded as initial stability measurement (intraoperative primary stability value) and posthealing stability measurement (postoperative secondary stability value) are important when evaluating the clinical performance of dental implants 4,6–9 . As well as its previous electronic cable version (Osstell), a newer magnetic wireless RF analyzer (Osstell Mentor) is also available.…”

The effect of marginal bone level changes on the stability of dental implants in a short‐term evaluation

“…; Güncü et al. ). ISQ changes during healing could be explained by bone formation and maturation (Güncü et al.…”

“…ISQ changes during healing could be explained by bone formation and maturation (Güncü et al. ). It is probable that implant stability after osseointegration (secondary stability) is related more to progressive incremental bone‐to‐implant contact than by mechanical anchorage (Merheb et al.…”

“…; Güncü et al. ), suggesting that RFA could be a sensitive method for detecting marginal bone loss. However, other authors have found no correlation between changes in implant stability quotient (ISQ) as measured by RFA and marginal bone loss in clinical 1‐year follow‐up studies (Turkyilmaz et al.…”