“…Several studies showed that in humans, a shorter adult LTL seems to be related to a suite of differences in behavior, including inactivity, obesity, smoking, alcohol intake, and higher stress reactivity ( Cherkas et al, 2008 ; Costa et al, 2015 ; Mundstock et al, 2015 ; Müezzinler et al, 2016 ; Astuti et al, 2017 ). Although some of these relations are based on single studies and may not be vigorous, physical activity, BMI, and smoking are based on the meta-analyses of many published studies ( Ulaganathan et al, 2018 ; Fairman et al, 2021 ; Kamolthip et al, 2021 ; Leman et al, 2021 ). Also, several studies revealed the possible role of environmental pollutants like air and traffic pollutants on LTL shortening; in a systematic review of more than 12,058 subjects, Zhao B et al revealed that air pollution reduced LTL ( Zhao et al, 2018 ), other studies also reported similar results about air pollution ( Lee et al, 2019 ; Niehoff et al, 2019 ) and this finding was also confirmed in several other studies about the role of traffic pollutants ( Hoxha et al, 2009 ), low to moderate exposure to lead ( Pawlas et al, 2015 ).…”