Relationship of prepartum plasma concentrations of estrone sulfate and estradiol‐17β with the weight of the calf and placental parameters in Holstein–Friesian cows

Abstract

The aim was to evaluate the relationship of prepartum plasma estrone sulfate (E1S) and estradiol-17b (E2b) concentrations with the weight of the calf and the placental parameters. Holstein-Friesian cows (n = 33) inseminated artificially with Japanese Black beef bull semen at Hiroshima University Farm in Japan were used for the experiment. Blood samples were taken every day from day 270 of gestation until the day after calving. The plasma samples were analyzed for E1S and E2b by enzyme immunoassay. The calf birth weight was taken immediately after calving. Complete fetal membranes were collected from 19 cattle and the weights of the placental components and the number of cotyledons were recorded. All 33 cattle delivered singleton normal calves. The prepartum plasma E1S concentration was found to correlate significantly (P < 0.01) with the calf birth weight (r = 0.83), total fetal membrane weight (r = 0.81), cotyledonary weight (r = 0.79) and inter-cotyledonary membrane weight (r = 0.64), but it did not correlate significantly with the number of cotyledons, whereas prepartum plasma E2b was not found to correlate significantly with the weight of either the calf or any of the placental components except the number of cotyledons. In conclusion, prepartum plasma E1S, not plasma E2b, was found to correlate significantly with the weight of the calf and the placental components. Figure 2 Relationship of the means of 10 days of prepartum maternal plasma estrone sulfate (E1S) and estradiol-17b (E2b) concentrations (x axis) with (a,b) cotyledonary weight, (c,d) inter-cotyledonary membrane weight and (e,f) number of cotyledons (y axis) in Holstein-Friesian cattle bearing singleton calves, P = < 0.01, (n = 19). RELATION BETWEEN ESTROGEN AND PLACENTA 493

Estrone Sulfate and Progesterone Profiles During Late Gestation in Recipient Cows Transferred Embryos Produced by Nuclear Transfer and In Vitro Fertilization

“…The patterns of changes in the concentrations of E 1 S in the NT and IVF cows of the present study were similar to previous studies in Holstein-Friesian cows inseminated artificially with Japanese black beef bull semen (AI cows); however, the E 1 S concentrations of both the NT and IVF cows were higher than those of AI cows [34]. The average calf birth weight and gestation length of AI cows are 33.6 ± 0.8 kg and 281.8 ± 0.8 days, respectively [36]. The calf birth weight and gestation length in the present study tended to be higher in the NT and IVF cows compared with those of AI cows.…”

“…The calf birth weight and gestation length in the present study tended to be higher in the NT and IVF cows compared with those of AI cows. Since the E 1 S concentration and calf birth weight have been reported to be positively and highly correlated with placental weight [15,17,36], the higher E 1 S concentrations, calf birth weights and gestation lengths of the NT and IVF cows in the present study might indicate a higher placental weight. It appears that the NT and IVF cows might have had large placentome syndrome (LPS).…”

Multilevel regulation of steroid synthesis and metabolism in the bovine placenta

“…The concentration of oestrone-sulphate and oestradiol-17b were found to be low in cows delivering stillborn calves, and this was suggested to be an indication of an abnormality of the placenta or of hormonal signals from the foetal calf to the placenta in the weeks before parturition Sorge et al, 2008). Lower plasma concentrations of oestradiol17b were also associated with retention of foetal/placental membranes; peak concentrations of oestradiol-17b at around parturition were lower in cows with retained placenta/foetal membranes (Wischral et al, 2001;Shah et al, 2007).…”