Relationship of health-related quality of life with fatigue and exercise capacity in patients with coronary artery disease

Staniūtė, Margarita; Bunevičius, Adomas; Brožaitienė, Julija; Bunevičius, Robertas

doi:10.1177/1474515113496942

Cited by 41 publications

(31 citation statements)

References 40 publications

(62 reference statements)

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“…It is unknown the actual mechanism responsible for the psychological effects of physical exercise, although it is recognized that it is an interaction of psychophysiological factors. In patients with coronary artery disease, for example, poor quality of life is associated to reduced exercise ability (14,15) and more tendency to fatigue (15). It is known that physical exercise is the main intervention used for physical fitness improvement and that it is positively related to quality of life (14,15,23,26).…”

Section: Discussionmentioning

confidence: 99%

“…In patients with coronary artery disease, for example, poor quality of life is associated to reduced exercise ability (14,15) and more tendency to fatigue (15). It is known that physical exercise is the main intervention used for physical fitness improvement and that it is positively related to quality of life (14,15,23,26). A systematic review to assess the association between physical activity and quality of life found that, in cross-sectional and longitudinal studies, the highest level of physical activity was related to a better perception of quality of life in apparently healthy adults or in different conditions of disease, regardless of sex (23).…”

Section: Discussionmentioning

confidence: 99%

“…Exercise is associated to a better HRQoL in different populations (14,15). However, few studies have investigated the effects of exercise on HRQoL of patients with sHT (16).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Exercise training improves quality of life in women with subclinical hypothyroidism: a randomized clinical trial

Werneck¹,

Coelho²,

Almas³

et al. 2018

Archives of Endocrinology and Metabolism

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Objective: The aim was to evaluate the quality of life (HRQoL) in women with subclinical hypothyroidism (sHT) after 16 weeks of endurance training. Subjects and methods: In the first phase, a cross-sectional study was conducted in which 22 women with sHT (median age: 41.5 (interquartile range: 17.5) years, body mass index: 26.2 (8.7) kg/m 2 , thyroid stimulating hormone > 4.94 mIU/L and free thyroxine between 0.8 and 1.3 ng/dL were compared to a group of 33 euthyroid women concerned to HRQoL. In the second phase, a randomized clinical trial was conducted where only women with sHT were randomly divided into two groups: sHT-Tr (n = 10)-participants that performed an exercise program-and sHT-Sed (n = 10)-controls. Exercise training consisted of 60 minutes of aerobic activities (bike and treadmill), three times a week, for 16 weeks. The HRQoL was assessed by the SF-36 questionnaire in the early and at the end of four months. Results: Women with sHT had lower scores on functional capacity domain in relation to the euthyroid ones (77.0 ± 23.0 vs. 88.8 ± 14.6; p = 0.020). The sHT-Tr group improved functional capacity, general health, emotional aspects, mental and physical component of HRQoL after training period, while the sHT-Sed group showed no significant changes. Conclusion: After 16 weeks of aerobic exercise training, there were remarkable improvements in HRQoL in women with sHT.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Exercise training improves quality of life in women with subclinical hypothyroidism: a randomized clinical trial

Werneck¹,

Coelho²,

Almas³

et al. 2018

Archives of Endocrinology and Metabolism

View full text Add to dashboard Cite

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“…Preliminary studies suggested feasibility of a rehabilitation program after a VTE episode [ 23 ]. Whether such programs have the potential to decrease fatigue, as is the case in patients with coronary artery disease, need to be studied prospectively [ 24 , 25 ].…”

Section: Discussionmentioning

confidence: 99%

A Qualitative Study to Appraise Patients and Family Members Perceptions, Knowledge, and Attitudes towards Venous Thromboembolism Risk

et al. 2015

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ObjectiveThis study aimed to examine perception, knowledge and concerns developed by patients and their family as regards venous thromboembolism (VTE) risk.MethodsWe conducted a qualitative study. Participants were: (1) patients with unprovoked VTE with either factor V Leiden mutation or G20210A prothrombin gene mutation or not; and (2) their first-degree relatives. Interviews took place mostly at Brest University Hospital. Participants produced narratives of the patient’s illness, stressing their perception of the disorder, its mechanisms, etiology, circumstances and risk factors. Interviews were audiotaped and transcribed verbatim. On an ongoing basis, central themes were identified and data from narratives were categorized by these themes.ResultsA total of ten patients and 25 first-degree relatives were interviewed. Analyses of patient’s narratives suggested 4 main themes: (1) concerns about initial symptoms and suspicion of VTE. The longer the duration of the initial phase, the more likely anxiety took place and persisted after diagnosis; (2) underestimation of potential life-threatening episode once being managed in emergency; (3) possible biographical disruption with inability to cope with the event; and (4) secondary prevention attitudes motivated by remains of the episode and favoring general prevention attitudes. Analyses of the first-degree relatives narratives suggested 3 main themes: (1) common interpretation of the VTE episode shared within the family; (2) diverse and sometimes confusing interpretation of the genetic status; and, (3) interpretation of clinical signs linked to VTE transmission within the family.ConclusionsConstruction of the risk of VTE is based on patient’s initial experience and shared within the family. Collection of narratives illustrates the gap between these perceptions and current medical knowledge. These results support the need to collect the perceptions of the VTE episode and its consequences, as a prerequisite to any health education process.

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“…The high-fatigue group degraded more than the low-fatigue group after discharge, but they still showed a significant improvement at the 12-month follow up. It is interesting that the intervention specifically improved the long-term mental functioning of the subjects with high fatigue because it is well known that fatigue impacts a person’s functioning [ 42 – 44 ]. This means that even though the high-fatigue group still had a lower level mental function than the low-fatigue group, the intervention tended to improve it long term.…”

Section: Discussionmentioning

confidence: 99%

One-year trajectories of mental and physical functioning during and after rehabilitation among individuals with disabilities

Preede

Sæbu²,

Perrin

et al. 2015

Health Qual Life Outcomes

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PurposeFirst, to evaluate the trajectories of physical and mental functioning in individuals with chronic disabilities receiving adapted physical activity-based rehabilitation. Second, to determine whether demographic factors, disability group, pain, fatigue and self-efficacy at baseline influenced these trajectories.Research designA prospective intervention study.MethodsThe study included 214 subjects with chronic disabilities who were admitted to a four-week adapted physical activity-based rehabilitation stay at Beitostølen Healthsports Centre. The subjects completed written questionnaires eight and four weeks before the rehabilitation, at admission to and discharge from the rehabilitation centre and again four weeks and 12 months after discharge. Multilevel models were performed to examine the trajectories of SF-12 physical and mental functioning with possible predictors.ResultsTime yielded a statistically significant effect on physical and mental functioning (p < 0.001). Low age (p = 0.002), no more than 2 h of personal assistance per week (p = 0.023), non-nervous system disability (p = 0.019), low pain level (p < 0.001) and high chronic disease-efficacy (p = 0.007) were associated with higher physical functioning. There was a greater improvement in physical functioning for subjects with lower chronic disease-efficacy at baseline (p = 0.036) and with a disability not associated with the nervous system (p = 0.040). Low fatigue (p = 0.001) and high chronic disease-efficacy (p = 0.004) predicted higher mental functioning. There was also a greater improvement in mental functioning for subjects with high fatigue (p =0.003) and low chronic disease efficacy at baseline (p = 0.032).ConclusionIndividuals with chronic disabilities who participated in an adapted physical activity-based intervention showed statistically significant increases in both physical and mental functioning across the 12 months after the intervention. The greatest improvement was among subjects with a high level of fatigue and low chronic disease-efficacy, as well as disabilities not associated with the nervous system, which has implications for the target groups in future rehabilitation.

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Relationship of health-related quality of life with fatigue and exercise capacity in patients with coronary artery disease

Abstract: In CAD patients undergoing rehabilitation, poor HRQoL is associated with greater fatigue and decreased exercise capacity independently from mental distress and CAD severity score.

Cited by 41 publications

References 40 publications

Exercise training improves quality of life in women with subclinical hypothyroidism: a randomized clinical trial

Exercise training improves quality of life in women with subclinical hypothyroidism: a randomized clinical trial

A Qualitative Study to Appraise Patients and Family Members Perceptions, Knowledge, and Attitudes towards Venous Thromboembolism Risk

One-year trajectories of mental and physical functioning during and after rehabilitation among individuals with disabilities

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