Relationship of electrocardiographic left ventricular hypertrophy to mortality and cardiovascular morbidity in high-risk patients

Abstract

In patients with CV disease simple, easily applicable ECG criteria for LVH identify a subset of individuals at particularly high risk for death and for heart failure.

Effects of ramipril on left ventricular mass and function in cardiovascular patients with controlled blood pressure and with preserved left ventricular ejection fraction

“…Left ventricular (LV) hypertrophy on electrocardiography or increased left ventricular mass (LVM) on echocardiography are strong predictors of death and nonfatal cardiovascular events in patients with hypertension, coronary heart disease, other cardiovascular diseases, and in the general population (1)(2)(3)(4)(5). Moreover, similar to other cardiovascular risk factors,…”

Risks of electrocardiographic left ventricular hypertrophy in hypertensive individuals and benefits of treatment-induced regression

“…The Heart Outcomes Prevention Evaluation (HOPE) trial examined the predictive value of Sokolow-Lyon voltage criteria in 9541 adults with established CV disease [5]. Patients meeting criteria for LVH had higher mean blood pressures than those without ECG LVH.…”

“…The HOPE trial demonstrated a potent relationship between Sokolow-Lyon voltage and HF [5]. In addition, given the relation of ECG strain and disease severity, it is not surprising that ECG strain predicts the development of HF.…”

Left ventricular mass and hypertrophy assessment by means of the QRS complex voltage-independent measurements

“…The resting electrocardiogram (ECG) is a simple, noninvasive and widely applicable method, useful for diagnosing of left ventricular hypertrophy (LVH) in different populations [1][2][3][4][5]. Numerous studies have documented electrocardiographic LVH to be a harbinger of greater morbidity and mortality, especially in patients with coronary artery disease [6].…”

“…For clinical purposes voltage-based ECG criteria, like Sokolow -Lyon or Framingham, have relatively low sensitivity for detection of increased left ventricular mass (LVM) [8,11,13,17]. However, despite their limitations, these indices are still employed in recent studies, especially in hypertensive patients [4,16].…”