Relationship between the Integrated Intensity of the Power Spectrum of Scattered Light and Tissue Blood Volume by the Dynamic Light Scattering Method

Abstract

The laser scattering characteristics from tissue microvasculature have been made clear by means of theoretical and experimental approaches. Our results show that the integrated intensity of the power spectrum correlates linearly with the volume of red blood cells in a given tissue provided the average collision number (m̄) between photons and moving red blood cells is less than unity. Also, the integrated intensity of the power spectrum is proportional to tissue blood volume if the density of red blood cells in blood (hematocrit) is constant.

Effects of Pulse-Synchronized Massage With Air Cuffs on Peripheral Blood Flow and Autonomic Nervous System

“…Peripheral BF was measured continuously by a laser Doppler flow-meter (ALF21 model, Advance Co, Japan), with a BF laser sensor 3,4 being applied to the underside of the third toes. The high-sensitivity photoelectric BF laser sensor uses an invisible semiconductor laser with a wavelength of 785 nm.…”

Measurement of Hemodynamics During Postural Changes Using a New Wearable Cephalic Laser Blood Flowmeter

“…A laser beam from the infrared laser diode of the laser Doppler flowmeter reaches the tissue scanned, and upon hitting moving red blood cells, changes its wavelength (Doppler shift). 17 The magnitude of the wavelength change is related to the number and velocity of the red blood cells. The recordings by this new device are well correlated with those by conventional laser blood flowmeters.…”

“…16 We developed a wearable cephalic BF (CBF) meter incorporating an ultra-miniature laser-Doppler blood flowmeter that can be worn on the tragus of the external ear to measure CBF during postural changes. 17,18 In the present study, we used this devise to estimate systemic hemodynamic parameters and symptoms of cephalic ischemia. Generally, BP is expressed as the product of BF and systemic vascular resistance.…”

New Finger-Occlusion Plethysmograph for Estimating Peripheral Blood Flow and Vascular Resistance

“…A laser beam (wave length: 780 nm) from the infrared laser diode of the LDF is carried by a fiber-optic probe to the investigated tissue and, upon hitting moving red blood cells, changes its wave length (Doppler shift). 17 The magnitude and frequency distribution of these wavelength changes are directly related to the number and velocity of the red blood cells. 17,18 The information is picked up by a returning fiber and converted to a voltage that corresponds to units of BF (ml · min -1 ·100 ml -1 of tissue).…”

“…17 The magnitude and frequency distribution of these wavelength changes are directly related to the number and velocity of the red blood cells. 17,18 The information is picked up by a returning fiber and converted to a voltage that corresponds to units of BF (ml · min -1 ·100 ml -1 of tissue). An ALF-21 can measure in a hemisphere to a tissue depth of 1 mm tissue and can be expressed in units of 0-100 ml·min -1 ·100 ml -1 .…”