Relationship between pulmonary function and peripheral vascular function in older Chinese: Guangzhou biobank cohort study-CVD

Pan, Jing; Xu, Lin; Lam, Tai Hing; Jiang, Chao Qiang; Zhang, Wei Sen; Zhu, Feng; Jin, Ya Li; Thomas, G. Neil; Cheng, Kar Keung; Adab, Peymané

doi:10.1186/s12890-018-0649-x

Cited by 9 publications

(11 citation statements)

References 43 publications

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“…On the other hand, when the factors were analyzed as continuous variables, CAVI and carotid IMT were inversely associated with FVC%-predicted and FEV1%-predicted by multivariate regression analysis, compared to ABI being positively associated. Interestingly, where this could indicate that strong associations between parameters of vascular and pulmonary function are initiated in early-stage atherosclerosis among relatively young participants prior to the diagnosis of COPD, these results are consistent with a previous report investigating older participants by multivariate regression analysis 27 ) .…”

Section: Discussionsupporting

confidence: 92%

Close Association between Subclinical Atherosclerosis and Pulmonary Function in Middle-Aged Male Smokers

Sugiura

Dohi

Takagi

et al. 2020

JAT

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Aims: Cigarette smoking provokes deleterious influences on cardiovascular and pulmonary systems, although the underlying relationship has not been sufficiently investigated especially in early-stage disease. The present study investigated possible associations between subclinical atherosclerosis and pulmonary function in middle-aged male smokers. Methods: Male smokers undergoing their periodic health check-up were enrolled in this study ( n = 3,775, 45 ± 8 years). Pulmonary function was evaluated using spirometry by calculating forced vital capacity (FVC) as a percentage of predicted value (FVC%-predicted), forced expiratory volume in one second (FEV1) as a percentage of predicted value (FEV1%-predicted), and the ratio of FEV1 to FVC (FEV1/FVC). Subclinical atherosclerosis was assessed based on ankle-brachial pressure index (ABI), cardio-ankle vascular index (CAVI), ultrasound examination of the carotid intima-media thickness (IMT), and presence of plaque. Results: Multivariate regression analysis showed that ABI was positively associated with FVC%-predicted and FEV1%-predicted after adjustment for confounders including smoking intensity, while CAVI or carotid IMT was inversely associated with both. Participants with chronic obstructive pulmonary disease (COPD, n = 256) showed reduced ABI and increased CAVI or carotid IMT compared with those without COPD, and participants with carotid plaque had lower pulmonary function than those without plaque. Reduced FEV1/FVC was an independent determinant of carotid plaque and decreased ABI was an independent determinant of COPD, as revealed by logistic regression analysis with the endpoint of carotid plaque presence or a diagnosis of COPD revealed. Conclusions: Middle-aged male smokers showed a close association between subclinical atherosclerosis and pulmonary function, implying that smoking induced-vascular and pulmonary damage are interacting in early-stage disease.

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Section: Discussionsupporting

confidence: 92%

Close Association between Subclinical Atherosclerosis and Pulmonary Function in Middle-Aged Male Smokers

Sugiura

Dohi

Takagi

et al. 2020

JAT

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“…The Caerphilly Prospective Study found lung function in mid-life to be a stronger predictor of arterial stiffness compared to later life in men [9]. A crosssectional association between arterial stiffness and reduced spirometry measures has also been found in general population studies where either c-f PWV or brachialankle PWV (ba-PWV) were found to be significantly and negatively associated with J o u r n a l P r e -p r o o f forced expiratory volume in 1 second (FEV 1 ) and forced vital capacity (FVC) [11][12][13].…”

mentioning

confidence: 71%

The association between carotid-femoral pulse-wave velocity and lung function in the Swedish CArdioPulmonary bioImage study (SCAPIS) cohort

Zaigham

Östgren

Persson

et al. 2021

Respiratory Medicine

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This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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“…3 Brachial-ankle pulse wave velocity and ankle-brachial index were shown to be inversely and dose-dependently associated with arterial stiffness in a group of older Chinese subjects. 4 It was found that poorer lung function as shown by reduced FEV1 was strongly associated with arterial stiffness as indicated by carotid to femoral pulse wave velocity (cf-PWV) in a large group when followed up for approximately 5 years. 5 Hypertension was shown to be variably associated with poor lung function due to restriction as well as obstructive type.…”

Section: Introductionmentioning

confidence: 99%

Association of Obstructive Parameters of Lung Functions Estimated by Spirometry with Risk Factors for Cardiovascular Disease among Women of Tertiary Care Hospital

Kavya¹,

Mavoori²,

Kumar³

et al. 2020

IJCDW

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Background Declining lung functions is associated directly with cardiovascular diseases like heart failure or coronary artery disease, or the risk factors leading to cardiovascular mortality like arterial stiffness, pulse wave velocity, hypertension, etc. Exclusive studies in women are not frequently performed. Aim The aim is to study the association between obstructive lung function estimated through spirometry and cardiovascular risk indicators like hypertension and arterial pulse wave velocity measured between carotid and femoral arteries (cf-PWV) in women. Methods A total of 30 postmenopausal women on regular treatment for hypertension were recruited in the study. They were subjected to spirometry and computerized cf-PWV estimation. Women were grouped according to modified global initiative for chronic obstructive lung disease (GOLD) criteria into three groups with increasing severity of obstructive lung function. Results Diastolic blood pressure (p = 0.04), pulse pressure (p < 0.0001), and cf-PWV (p = 0.009) were found to be significantly different between the three groups. Negative correlation existed between cf-PWV and %pred forced expiratory volume in 1 second (FEV1) in the group with most severe obstructive lung function (Pearson correlation coefficient r = 0.7610 was significant at p = 0.01). The strength of this negative association decreased as the severity deceased (r = 0.5603, significant at p = 0.03). Conclusion Strong association between severity of obstructive lung function in postmenopausal women with pulse pressure was in lines with previous studies, but the diastolic blood pressure being associated is a novel finding. Also, the degree of obstructive lung function is positively associated with arterial stiffness which is an important indicator for impending cardiovascular mortality.

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Relationship between pulmonary function and peripheral vascular function in older Chinese: Guangzhou biobank cohort study-CVD

Cited by 9 publications

References 43 publications

Close Association between Subclinical Atherosclerosis and Pulmonary Function in Middle-Aged Male Smokers

Close Association between Subclinical Atherosclerosis and Pulmonary Function in Middle-Aged Male Smokers

The association between carotid-femoral pulse-wave velocity and lung function in the Swedish CArdioPulmonary bioImage study (SCAPIS) cohort

Association of Obstructive Parameters of Lung Functions Estimated by Spirometry with Risk Factors for Cardiovascular Disease among Women of Tertiary Care Hospital

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