Relationship Between Operative Procedure and Prognosis of Patients with Interlobar Invading Lung Cancer Lesions.

Abstract

General Hospital* A total of 65 patients who had interlobar invading lung cancer lesions underwent surgical resection. The 5-year survival rate of these cases was 42%. Of the 65 patients, the 52 patients who were treated with complete resection had a significantly higher survival rate than the 13 patients who underwent incomplete resection (52% vs. 0%). Of the 52 patients who were treated with complete resection, the 5-year survival rate of the 28 patients who underwent lobectomy of the invaded lobes (Group A) was significantly higher than that of the remaining 24 patients who underwent partial resection of such lobes (Group B) (74% vs. 27%). In particular, there was a significant difference between these two groups in adenocacinoma, in NO cases, and in N1 cases. Causes of death were compared between Group A and Group B according to nodal involvement. Almost all of the N2 cases in both groups died of distant metastasis. However, in N1 and NO cases, the recurrence rate in the ipsilateral hemithorax and the mortality of Group A were lower than those of Group B. To improve the survival rate of patients with interlober invading lung cancer lesions , bilobectomy or pneumonectomy should be performed. However, in patients 70 years of age or older, pneumonectomy is not recommended, since it did not improve the survival rate of such elderly patients.

Outcome Following Surgery for Primary Lung Cancer with Interlobar Pleural Invasion

“…Sagawa et al reported that survival was worse after a lobectomy with a partial resection than after a bilobectomy. 11 Sensaki et al showed that local recurrence was observed in patients after a lobectomy with a partial resection but was not seen in patients after a bilobectomy. 7 Meanwhile, Morita et al and Okada et al described that postoperative survival did not differ between patients who received a lobectomy with a partial resection and those with either a bilobectomy or pneumonectomy.…”

Surgical Management of Non-Small Cell Lung Cancer Invading the Fissure: Less Is More?

“…More than 25 years ago, 2 studies from Japan reported increased local recurrence rates and worse survival with PSR compared with MR for cases in which tumor crossed into another lobe. 8,9 Concluding differently, Nonaka and colleagues 10 in 2005 described no difference in local recurrence or postoperative prognosis between bilobectomy or pneumonectomy and lobectomy with partial resection in a group of 50 patients from a cohort of 322 patients with primary lung cancer.…”