Relationship between limited joint mobility of the hand and diabetic foot risk in patients with type 2 diabetes

Mineoka, Yusuke; Ishii, Michiyo; Tsuji, Akiko; Komatsu, Yoriko; Katayama, Yuko; Yamauchi, Mitsuko; Yamashita, Aki; Hashimoto, Yoshitaka; Nakamura, Naoto; Katsumi, Yoshiki; Isono, Motohide; Fukui, Michiaki

doi:10.1111/1753-0407.12460

Cited by 14 publications

(9 citation statements)

References 48 publications

(117 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Furthermore, the economic burden of treatment for complications is so high [31]. In the several risk factors for foot ulceration with diabetes [4][5][6][7][8][9]22], recognition of diabetic neuropathy and PAD is especially important to prevent diabetic foot ulcer [3,10]. Early recognition and management of risk factors can prevent or delay adverse outcomes of diabetic foot [32].…”

Section: Discussionmentioning

confidence: 99%

“…The IWGDF classification was used to categorized the risk of diabetic foot: group 0 (no neuropathy), group 1 (neuropathy), group 2 (neuropathy, vascular disease or deformity), and group 3 (previous ulcer) [21]. As previously reported, we thought patients in group 0 to be at "low risk" for foot ulceration, whereas those in groups 1-3 to be at "high risk" [22,23]. Foot ulcer was defined as a full-thickness skin defect associated with neuropathy and/or peripheral arterial disease (PAD) of the lower limbs that required >14 days for healing [21,24,25].…”

Section: Foot Risk Classification and Definition Of Foot Ulcermentioning

confidence: 99%

See 1 more Smart Citation

Platelet to lymphocyte ratio correlates with diabetic foot risk and foot ulcer in patients with type 2 diabetes

et al. 2019

Self Cite

View full text Add to dashboard Cite

Diabetic foot ulcer is a major complication in patients with diabetes. Platelet-lymphocyte ratio (PLR) has been reported to have a predictive effect to some diabetic complications in recent years. However, it has not been fully elucidated about the relationship between diabetic foot risk or diabetic foot ulcer and PLR in patients with type 2 diabetes. Therefore, we aimed to evaluate this relationship. In this cross-sectional study, we evaluated the relationships between patient's diabetic foot risk with the criteria of the International Working Group on the Diabetic Foot (IWGDF) and prevalent foot ulcer, and PLR in 453 consecutive patients with type 2 diabetes. Propensity score analysis was used to adjust the difference of covariates; age, sex, duration of diabetes, body mass index (BMI), HbA1c, current smoking, hypertension, dyslipidemia, neuropathy, PAD, foot deformity and history of foot ulcers. PLR was higher in patients with high risk diabetic foot or foot ulcer (117 ± 40 vs. 107 ± 31, p = 0.003 and 148 ± 65 vs. 113 ± 56, p < 0.001). A receiver-operating characteristic curve demonstrated that PLR of 130.6 constitutes the cutoff value for prevalent foot ulcer with sensitivity 0.85 and specificity 0.70. Multivariate logistic regression analysis revealed that PLR was positively correlated with prevalent foot ulcer (odds ratio, 1.02; 95% confidence interval 1.01-1.04, p = 0.003) after adjusted for several variables with propensity score analysis. Our results demonstrated that PLR can be a marker for high risk diabetic foot and diabetic foot ulcer in patients with type 2 diabetes.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Foot Risk Classification and Definition Of Foot Ulcermentioning

confidence: 99%

Platelet to lymphocyte ratio correlates with diabetic foot risk and foot ulcer in patients with type 2 diabetes

et al. 2019

Self Cite

View full text Add to dashboard Cite

show abstract

“…Retinopathy was assessed by chart review and graded as follows: no diabetic retinopathy, simple diabetic retinopathy, and proliferative diabetic retinopathy 23. Neuropathy was diagnosed using criteria for diabetic neuropathy proposed by the Diagnostic Neuropathy Study Group 24.…”

Section: Methodsmentioning

confidence: 99%

Japanese radio calisthenics prevents the reduction of skeletal muscle mass volume in people with type 2 diabetes

Kimura

Okamura

Iwai

et al. 2020

BMJ Open Diab Res Care

Self Cite

View full text Add to dashboard Cite

ObjectiveReduction of muscle mass and strength is an important treatment target for patients with type 2 diabetes. Recent studies have reported that high-intensity resistance training improves physical function; however, all patients found it difficult to perform high-intensity resistance training. Radio calisthenics, considered as therapeutic exercises to promote health in Japan, are simple exercises that can be performed regardless of age and help move the muscles and joints of the whole body effectively according to the rhythm of radio. We investigated the efficacy of radio calisthenics for muscle mass in patients with type 2 diabetes in this retrospective cohort study.Research design and methodsA total of 42 hospitalized patients with type 2 diabetes were recruited. The skeletal muscle mass index (SMI, kg/m2) was calculated as appendicular muscle mass (kg) divided by height squared (m2). We defined the change of SMI as the difference of SMI between the beginning and end of hospitalization.ResultsAmong 42 patients, 15 (11 men and 4 women) performed radio calisthenics. Body weights of both radio calisthenics exercisers and non-exercisers decreased during hospitalization. The change of SMI was significantly lesser in radio calisthenics exercisers than in non-exercisers (7.1±1.4 to 7.1±1.3, –0.01±0.09 vs 6.8±1.1 to 6.5±1.2, –0.27±0.06 kg/m2, p=0.016). The proportion of decreased SMI was 85.2% (23/27 patients) in non-radio calisthenics exercisers, whereas that in radio calisthenics exercisers was 46.7% (7/15 patients).ConclusionsRadio calisthenics prevent the reduction of skeletal muscle mass. Thus, radio calisthenics can be considered effective for patients with type 2 diabetes.

show abstract

“…In this study, we identified that NLR correlated with LJM of hand in patients with type 2 diabetes. LJM of hand, which is associated with diabetic micro- [1][2][3][4]7] and macrocomplications [8,9,40], is relatively easy to notify; however, clinicians often overlook this complication of diabetes in clinical situations [6]. NLR, which calculated simply and easily in routine clinical practice, could be used as a marker of diabetic complications including LJM of hand.…”

Section: Discussionmentioning

confidence: 99%

Neutrophil-lymphocyte ratio correlates with limited joint mobility of hand in patients with type 2 diabetes

et al. 2018

Self Cite

View full text Add to dashboard Cite

Limited joint mobility (LJM) of hand, which is one of the complications of diabetic hand, is associated with diabetic micro- and macroangiopathy although the precise pathogenesis is not completely understood. Neutrophil-lymphocyte ratio (NLR), a simple and novel inflammatory marker, has been reported to have a predictive effect to some diabetic complications in recent years. However, it is not elucidated about the relationship between LJM of hand and NLR in patients with type 2 diabetes. We evaluated the relationships between LJM of hand and NLR in 335 consecutive patients with type 2 diabetes in this cross-sectional study. LJM of hand was diagnosed by a 'prayer sign' or 'table test'. LJM of hand was present in 80 patients. The patients with LJM of hand had significantly older age, longer duration of diabetes, worse renal function, and higher proportion of diabetic neuropathy, retinopathy and nephropathy. NLR in patients with LJM of hand was higher than that in patients without LJM of hand (2.54 ± 1.46 vs. 2.11 ± 1.04, p = 0.004). Multivariate logistic regression analysis revealed that LJM of hand was positively correlated with NLR (odds ratio, 1.31; 95% confidence interval 1.03-1.69, p = 0.027) after adjustment for age, sex, duration of diabetes, body mass index, hemoglobin A1c, hypertension and dyslipidemia. Our results demonstrate a positive relation between LJM of hand and NLR in patients with type 2 diabetes.

show abstract

Relationship between limited joint mobility of the hand and diabetic foot risk in patients with type 2 diabetes

Abstract: The results demonstrate a correlation between LJM of the hand and foot risk. Diagnosis of diabetic hand is simple and non-invasive, and is thus a useful method for assessing the risk of diabetic foot in T2D patients.

Cited by 14 publications

References 48 publications

Platelet to lymphocyte ratio correlates with diabetic foot risk and foot ulcer in patients with type 2 diabetes

Platelet to lymphocyte ratio correlates with diabetic foot risk and foot ulcer in patients with type 2 diabetes

Japanese radio calisthenics prevents the reduction of skeletal muscle mass volume in people with type 2 diabetes

Neutrophil-lymphocyte ratio correlates with limited joint mobility of hand in patients with type 2 diabetes

Contact Info

Product

Resources

About