Relationship between haemodialysis anaemia and copper and zinc

Hosokawa, Shinichi; Nishitani, Hiroshi; Umemura, Kisaburo; Nishio, Toshihiro; Tomoyoshi, T; Sawanishi, K; Yoshida, Osamu

doi:10.1007/bf02083507

Cited by 9 publications

(5 citation statements)

References 13 publications

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“…Proteinuria in renal failure leads to excessive excretion of zinc (3) . On the other hand, the present study found that Zn level was significantly increased after dialysis, this results agrees with Hosokawa et al, in 1985 (9) , who found that serum zinc concentration increases `after dialysis.…”

Section: Discussionsupporting

confidence: 93%

Assessment of Serum Chromium and Zinc Levels in Patients with Chronic Renal Failure

Rahamtalla¹

2019

SMLJ

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Background: Chromium (Cr) and Zinc (zn) are very important in human nutrition. Many researchers reported that serum chromium and serum zinc are impaired in patients with chronic renal failure,(CRF). Objectives: This study aimed to assess chromium and Zinc in chronic renal failure patients. Materials and Methods: This study was conducted at Khartoum state during November 2017 to May 2018.The study enrolled 35 patients with CRF and 40 healthy controls. Serum Chromium and Zinc levels were estimated using Atomic absorption spectrophotometry, (AAS), technique. Results: the current study demonstrated a highly significant a lower level of Cr in patients in contrast to healthy controls, (0.032 versus 0.147 mg/dl; respectively, P<0.001), and also of Zn level in patients as compared to healthy controls (0.165 versus 0.564 mg/dl; respectively, P<0.001). In contrary, the level of both Cr and Zn were significantly higher after dialysis as compared to their levels, before dialysis (0.137 versus 0.032 mg/dl; respectively, P<0.001) and (0.253 versus 0.165 mg/dl; respectively, P<0.001) for Cr and Zn, respectively. Conclusion: The present study revealed that, Zn and Cr levels decreased in CRF patients and increased after dialysis.

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Section: Discussionsupporting

confidence: 93%

Assessment of Serum Chromium and Zinc Levels in Patients with Chronic Renal Failure

Rahamtalla¹

2019

SMLJ

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“…The erythrocyte Zn concentration in patients with chronic renal failure (CRF) was reported to be low [8], normal (3 papers) [17], but more often increased [18,19,22,29]. High erythrocyte Zn in the presence of low plasma Zn in patients with renal failure is probably in relation to the activity of the major Zn-containing erythrocyte enzyme carbonic anhydrase.…”

Section: Zincmentioning

confidence: 99%

Trace Elements in End-Stage Renal Disease

Zima¹,

Tesař²,

Mestek

et al. 1999

Blood Purif

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For human beings trace elements are essential nutrients with a gamut of functions. They are for instance indispensable components of many enzymes, so they have some regulatory functions and they may affect immune reactions and free radical generation. Abnormalities of trace elements are primarily the result of uremia, and they may be further modified and sometimes greatly exacerbated by the dialysis procedure. The role of trace elements in hemodialysis (HD) patients has not yet been fully characterized. To prevent some complications in chronic HD patients, it is very important to regulate the levels of trace elements by adequate water treatment. Reverse osmosis is able to prevent the accumulation of the majority of trace elements in the patients. Zinc supplementation may be recommended for patients with proven zinc deficiency, but for all chronic renal failure patients it is questionable. Selenium deficiency is to be suspected in dialyzed patients and selenium supplementation may be beneficial (increasing glutathione peroxidase activity, cardioprotective effect, immunostimulatory properties) for chronic renal failure patients. Supplementation with a trace element may be indicated when its depletion was unequivocally documented and when there is evidence of the positive effects of this element on the quality of life of the dialyzed patients.

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“…Previously, we and others reported that abnormalities of aluminum [1][2][3][4], silicon [5][6][7][8], zinc [9][10][11][12], manganese [13][14][15][16] and nickel [17][18][19][20] caused various kinds of compli cations in chronic hemodialysis (HD) patients. Elevated serum Al levels in chronic HD patients [1][2][3][4] were asso ciated with encephalopathy [3].…”

Section: Introductionmentioning

confidence: 99%

Trace Elements and Complications in Patients Undergoing Chronic Hemodialysis

Hosokawa

Oyamaguchi

Yoshida

1990

Nephron

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Abnormalities of trace elements such as aluminum, silicon, zinc, manganese and nickel were found in chronic hemodialysis (HD) patients. The relationship between serum concentration of trace elements and complications such as anemia bone disease, neurological disorder and nutritional disorder in 100 chronic HD patients was examined. Serum Al and Si levels were very high in these patients, and were negatively correlated with indicators of anemia such as RBC, hemoglobin and hematocrit values. Serum Al and Si levels in the HD patients with peripheral neurological disorder (excluding encephalopathy) and with bone disease were significantly high. The levels of serum Zn, Mn and Ni were low, and were correlated with total serum protein levels. In summary, in order to prevent some complications in chronic HD patients, it is very important to regulate levels of trace elements.

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Relationship between haemodialysis anaemia and copper and zinc

Cited by 9 publications

References 13 publications

Assessment of Serum Chromium and Zinc Levels in Patients with Chronic Renal Failure

Assessment of Serum Chromium and Zinc Levels in Patients with Chronic Renal Failure

Trace Elements in End-Stage Renal Disease

Trace Elements and Complications in Patients Undergoing Chronic Hemodialysis

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