Relationship between fluoride release rate and anti-cariogenic biofilm activity of glass ionomer cements

Chau, Ngoc Phuong Thanh; Pandit, Santosh; Cai, Jian-Na; Jeon, Jongho

doi:10.1016/j.dental.2014.12.016

Cited by 38 publications

(27 citation statements)

References 34 publications

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“…GIC is a restorative material that shows good chemical adhesion to the dental structure, releases fluorine (Cassanho et al, ; Weng, Guo, Gregory, & Xie, ), enables restoration of fluorine after topical applications, alters acid production and the electrolytic metabolism of cariogenic microorganisms, and promotes a decrease in the number of S. mutans and plaque bacteria after restoration (Chau, Pandit, Cai, Lee, & Jeon, ). The fluorine released by GIC can alter the ecosystem of the bacterial plaque and affect a variety of enzymatic functions that are vital for the bacterial cell, including inhibition of enolase, phosphatase, and pyrophosphatase, eventually leading to cell death (Chau et al, ; Duque, Negrini, Hebling, & Spolidorio, ; Hotwani, Thosar, Baliga, Bundale, & Sharma, 2013). Furthermore, the acid–base reaction during the gelling process results in a drop in the pH of GIC, thereby promoting the acidity of the medium and creating unfavorable growth conditions for the bacteria (Farrugia & Camilleri, ; Prabhakar, Prahlad, & Kumar, ).…”

Section: Introductionmentioning

confidence: 99%

“…On the other hand, studies on the effects of zinc oxide nanoparticles associated with glass ionomer cement (GIC) are scarce (Spencer, Campbell, Buschang, Cai, & Honeyman, 2009), although such data would be important. GIC is a restorative material that shows good chemical adhesion to the dental structure, releases fluorine (Cassanho et al, 2005;Weng, Guo, Gregory, & Xie, 2010), enables restoration of fluorine after topical applications, alters acid production and the electrolytic metabolism of cariogenic microorganisms, and promotes a decrease in the number of S. mutans and plaque bacteria after restoration (Chau, Pandit, Cai, Lee, & Jeon, 2015). The fluorine released by GIC can alter the ecosystem of the bacterial plaque and affect a variety of enzymatic functions that are vital for the bacterial cell, including inhibition of enolase, phosphatase, and pyrophosphatase, eventually leading to cell death (Chau et al, 2015;Duque, Negrini, Hebling, & Spolidorio, 2005;Hotwani, Thosar, Baliga, Bundale, & Sharma, 2013).…”

Section: Introductionmentioning

confidence: 99%

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Antibacterial activity of glass ionomer cement modified by zinc oxide nanoparticles

Garcia

Cardia

Francisconi

et al. 2016

Microscopy Res & Technique

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This study evaluated the antibacterial activity of zinc oxide nanoparticles incorporated into self-cured glass ionomer cement (GIC) and light-cured resin-reinforced GIC on Streptococcus mutans biofilm. The GICs, Fuji II (GC America) and Fuji II LC (GC America), were incorporated with nanoparticles at concentrations of 0%, 1%, and 2% by weight, and the biofilm maturation time was one and seven days. Circular specimens of each GIC type were prepared. The antibacterial activity was evaluated by determining the number of colony forming units of S. mutans strain per milliliter. Morphology of the biofilm was analyzed by scanning electron microscopy (SEM). The data obtained for each GIC were analyzed by two-way ANOVA (α = 5%). For chemically activated GIC, no significant difference was observed in relation to the time of biofilm maturation (p = 0.744), concentration of nanoparticles (p = 0.966), and their interaction (p = 0.800). The results from analysis of GIC modified by light-polymerized resin showed that only of the maturing time significantly affected the number of adhered cells on the biofilm (p = 0.034, F = 4.778). The more mature the biofilm, higher the number of cells. SEM analysis showed no change in cell morphology in relation to the type of GIC, maturation time, and nanoparticles concentration. We conclude that the inclusion of zinc oxide nanoparticles at concentrations of 1% and 2% by weight into the GICs evaluated here, did not promote their antimicrobial activity against S. mutans.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Antibacterial activity of glass ionomer cement modified by zinc oxide nanoparticles

Garcia

Cardia

Francisconi

et al. 2016

Microscopy Res & Technique

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“…[9] In a study conducted by Chau et al, results suggest that the anti-cariogenic biofilm activity of GICs is closely correlated with their fluoride release rate during biofilm formation. [10,11] The antimicrobial activity of the GICs could be related to the synergistic action of acid and fluoride release of the cement …”

Section: Discussionmentioning

confidence: 99%

Effect of Acid and Fluoride Release from Four Glass Ionomer Cements on Streptococcus mutans: An In Vitro Study

Mahuli¹,

Mahuli²,

Ramanarayanan³

et al. 2015

IJDHC

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Objectives:The objective was to evaluate fluoride and acid release from four glass ionomer cements (GICs) over time and to evaluate and compare their effect on Streptococcus mutans over time. Materials and Methods: The fluoride and acid release from the prepared samples (GICs, Miracle Mix, Fuji IX, d-tech ® , Ketac Molar) were measured daily using digital fluoride meter and pH meter, respectively, after placing them in deionized distilled water for 15 days. The water was replaced daily. The samples were aged by placing them in distilled water for 1, 3, 5, and 7 days. The antimicrobial activity was assessed by measuring the zone of inhibition around the samples (fresh and aged) placed on the bacterial cultures after 48 h of incubation. Mean and standard deviation were calculated. Pearson's correlation coefficient was used. P < 0.05 was considered statistically significant. Results: The antimicrobial activity of the four GICs was greatest immediately after the cements were mixed. The greatest fluoride and acid release was from d-tech. Conclusion: Both acid and fluoride release that contributed to the antibacterial activity of the Glass ionomer cements reduced significantly as the cement aged.

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“…GI presented a chemical adhesion to the moist tooth structure with low coefficient of thermal expansion close to the tooth structure, in addition to fluoride release which is knowing for many years to have an antibacterial action [10,11] . In spite of these advantages, the internal cracks, air voids and high porosity of GI may allow the microleakage occurrence leading to secondary caries [12,13] .…”

Section: Introductionmentioning

confidence: 99%

Comparative evaluation of the antibacterial activity of Glass ionomer restoration incorporated with different metal oxides Nanoparticles on oral Streptococcus mutans

Ezzeldin

Elshishtawy

El-Borady

et al. 2019

Egyptian Dental Journal

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Relationship between fluoride release rate and anti-cariogenic biofilm activity of glass ionomer cements

Cited by 38 publications

References 34 publications

Antibacterial activity of glass ionomer cement modified by zinc oxide nanoparticles

Antibacterial activity of glass ionomer cement modified by zinc oxide nanoparticles

Effect of Acid and Fluoride Release from Four Glass Ionomer Cements on Streptococcus mutans: An In Vitro Study

Comparative evaluation of the antibacterial activity of Glass ionomer restoration incorporated with different metal oxides Nanoparticles on oral Streptococcus mutans

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