Comparative evaluation of the antibacterial activity of Glass ionomer restoration incorporated with different metal oxides Nanoparticles on oral Streptococcus mutans

Background It has been noticed that failure of composite resin restorations can be attributed to either of the two following causes: fracture or secondary caries. For that reason, it is mandatory to formulate a restorative material with antibacterial effect. An Octenidine dihydrochloride (OCT) has been assessed as an alternative to antimicrobial material, such as chlorhexidine due to their higher microbicidal effect and lless cytotoxicity. Objective current study aimed to add different concentrations of Octenidine dihydrochloride into experimental flowable resin composite and evaluate its antibacterial activity over different periods of time to provide the manufacturers with more precise information. Methods a flowable resin composite material mix was formulated. Octenidine dihydrochloride antibacterial material was then added separately to the formulated mix at 1% wt. and 1.5% wt. concentration respectively. Antibacterial activity was assessed against streptococcus mutans using agar diffusion test and compared to a commercial resin composite. Results it showed that by increasing the percentage of incorporated Octenidine dihydrochloride (1% and 1.5% ) respectively, the antibacterial efficacy against the streptococcus mutans increased. Results of this study also showed the time had a significant decrease in the antibacterial effect. Conclusions it can be concluded that by the incorporation of Octenidine dihydrochloride (1% and 1.5% ) respectively, the antibacterial efficacy against the streptococcus mutans increased. Time had a significant decrease in the antibacterial effect of OCT.

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Comparative evaluation of the antibacterial activity of Glass ionomer restoration incorporated with different metal oxides Nanoparticles on oral Streptococcus mutans

Cited by 5 publications

References 35 publications

A review on biomedical and dental applications of cerium oxide nanoparticles ― Unearthing the potential of this rare earth metal

A review on biomedical and dental applications of cerium oxide nanoparticles ― Unearthing the potential of this rare earth metal

Metal oxide nanoparticles modified glass ionomer cement: A short review

RETRACTED: The effect of Octenidine dihydrochloride on the antibacterial activity of a formulated resin composite. An invitro study

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