Relationship between clinical signs and early lesions of contagious caprine pleuropneumonia caused by Mycoplasma strain F38

Wesonga, Hezron; Litamoi, J. K.; Kagumba, M; Wakhusama, Evalyn M.

doi:10.1016/0921-4488(93)90106-r

Cited by 13 publications

(10 citation statements)

References 11 publications

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“…Pathological findings, though capable of contributing to a diagnosis were not confirmatory either, because of the limited range of responses of which the lung is capable and the changes evoked by the different caprine pneumopathic agents are generally not sufficiently pathognomonic (Jones 1989). The gross and histopathological lesions observed were similar with those of MacOwan and Minette (1976), Abubakar et al (1984), Kibor (1990), Wesonga et al (1993) and Johnson et al (2002).…”

Section: Discussionsupporting

confidence: 89%

A study on Contagious Caprine Pleuropneumonia (CCPP) in goats at an export oriented abattoir, Debrezeit, Ethiopia

Eshetu

Yigezu

Asfaw

2007

Trop Anim Health Prod

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300 goat serum samples from an export-oriented abattoir were tested for contagious caprine pleuropneumonia antibodies by the complement fixation test. The disease prevalence was 31% with no significant differences (P > 0.05) between the regions "Borena", "Bale", "Afar" and "Jinka" or the age of the goats (P > 0.05). Gross pathology and histopathology of the lung primary lesions were indicative of pleuropneumonia caused by Mycoplasma capricolum subsp. capripneumoniae.

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Section: Discussionsupporting

confidence: 89%

A study on Contagious Caprine Pleuropneumonia (CCPP) in goats at an export oriented abattoir, Debrezeit, Ethiopia

Eshetu

Yigezu

Asfaw

2007

Trop Anim Health Prod

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“…Paraffin sections of the lungs of 6 goats that died with acute fibrinous pneumonia in the early phase of CCPP and with M. capripneumoniae confirmed on culture [36,35] were positive control tissues. For control of antigenic specificity of the primary antiserum, the following procedures were performed: the antiserum was (i) absorbed with M. capripneumoniae antigen (2 ml antiserum mixed with 0.2 mg antigen, kept at +4°C overnight and centrifuged) and then applied diluted 1:100 and 1:200; (ii) substituted by normal rabbit serum (Dako); (iii) applied on sections of pneumonic goat lungs with M. ovipneumoniae, M. capricolum, M. mycoides subsp.…”

Section: Methodsmentioning

confidence: 99%

Experimental Contagious Caprine Pleuropneumonia: A Long Term Study on the Course of Infection and Pathology in a Flock of Goats Infected with Mycoplasma capricolum subsp. capripneumoniae

et al. 2004

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: Experimental contagious caprine pleuropneumonia: A long term study on the course of infection and pathology in a flock of goats infected with Mycoplasma capricolum subsp. capripneumoniae. Acta vet. scand. 2004, 45, 167-179. -Contagious caprine pleuropneumonia (CCPP) is a major threat to goat farming in parts of Africa and Asia. It classically causes acute high morbidity and mortality early in infection, but little is known of its long term epizootiology and course. In this study, 10 goats were inoculated with Mycoplasma capricolum subsp. capripneumoniae (M. capripneumoniae) and then mixed with 15 goats for contact transmission. The disease course was monitored in each goat for 56-105 days, whereafter the goats were killed and necropsied. Varying features signifying infection occurred in altogether 17 goats (7 inoculated, 10 in-contact). Clinical signs were severe in 8 goats but no fatalities occurred. Only 6 goats had serum antibody titres against M. capripneumoniae in ELISA. Fourteen goats (5 inoculated, 9 in-contact) had chronic pleuropulmonary lesions compatible with CCPP at necropsy and 7 of those showed M. capripneumoniae antigen in the lung by immunohistochemistry. Neither cultivation nor PCR tests were positive for the agent in any goat. The results indicate that the clinical course of CCPP in a flock may be comparatively mild, M. capripneumoniaeassociated lung lesions may be present at a late stage of infection, and chronic infection may occur without a significant serological response. goat; Mycoplasma; contagious pleuropneumonia; ELISA; immunohistochemistry; serology; pathology.

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“…Similar to other reports, a thickened pericardium was sometimes seen. 6,13,22 In the more advanced cases, there was a black discoloration of the lung tissues and sequestration of necrotic areas with some interlobular edema of the lungs. 10 Histologic examination of the lungs showed a fibrinopurulent pleuropneumonia with diffuse, mild vascular and parietal alveolar congestion and diffuse fibrinous deposits in the alveolar septa.…”

Section: Case Reportmentioning

confidence: 98%

Contagious Caprine Pleuropneumonia Outbreak in Captive Wild Ungulates at Al Wabra Wildlife Preservation, State of Qatar

Arif¹,

Schulz²,

Thiaucourt³

et al. 2007

Journal of Zoo and Wildlife Medicine

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Contagious caprine pleuropneumonia (CCPP) caused by Mycoplasma capricolum subsp. capripneumoniae is a highly contagious and serious respiratory disease of domestic goats, characterized by coughing, severe respiratory distress, and high mortality rates. The lesions at necropsy are mainly a fibrinous pleuropneumonia with increased straw-colored pleural fluid. An outbreak of CCPP in wild goat (Capra aegagrus), Nubian ibex (Capra ibex nubiana), Laristan mouflon (Ovis orientalis laristanica), and gerenuk (Litocranius walleri) occurred at Al Wabra Wildlife Preservation in the State of Qatar. The disease was suspected because of the clinical symptoms and the necropsy findings and was confirmed by the isolation and identification of the causative organism. This new finding indicates that CCPP should be considered a potential threat to wildlife and the conservation of endangered ruminant species, especially in the Middle East, where it is enzootic because of its presence in chronic carriers. Susceptible imported animals should be quarantined and vaccinated. The preferred samples for diagnosis are the pleural fluid, which contains high numbers of Mycoplasma, and sections of hepatized lung, preferably at the interface of normal and diseased tissues. Samples must be shipped to diagnostic laboratories rapidly, and appropriate cool conditions must be maintained during shipping.

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Relationship between clinical signs and early lesions of contagious caprine pleuropneumonia caused by Mycoplasma strain F38

Cited by 13 publications

References 11 publications

A study on Contagious Caprine Pleuropneumonia (CCPP) in goats at an export oriented abattoir, Debrezeit, Ethiopia

A study on Contagious Caprine Pleuropneumonia (CCPP) in goats at an export oriented abattoir, Debrezeit, Ethiopia

Experimental Contagious Caprine Pleuropneumonia: A Long Term Study on the Course of Infection and Pathology in a Flock of Goats Infected with Mycoplasma capricolum subsp. capripneumoniae

Contagious Caprine Pleuropneumonia Outbreak in Captive Wild Ungulates at Al Wabra Wildlife Preservation, State of Qatar

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