Relationship between anemia, quality of life, and laboratory indices in hemodialysis patients

Sadeghi, Mahdi; Ebrahimi, Hossein; Abbasi, Mehrshad; Norouzadeh, Reza

doi:10.4103/1319-2442.190905

Cited by 9 publications

(11 citation statements)

References 2 publications

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“…20 Some factors such as stenosis of the end of veins of arteriovenous fistula, poor and weak fistula, lack of following the schedule of dialysis by the patient, cardiovascular diseases, hemodynamic instability, infections, malignancies, re-circulation and reuse of dialysis filter can be the important causes of low dialysis adequacy. 21 The mean Kt/V was around 1.0 in this present study. The KDQOI recommendation is Kt/V t1.2 per dialysis session.…”

Section: Discussionsupporting

confidence: 56%

Dialysis Adequacy and Quality of Life in Diabetic and Non-diabetic Bangladeshi Patients on Maintenance Hemodialysis

et al. 2019

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Background: Quality of life (QOL) is one of the chief areas to be addressed when caring for people with end stage renal disease (ESRD). The continual excretory function of native kidneys are replaced in such patients by few hours of rapid urea clearance in a week. This study aimed to explore whether more weekly hemodialysis sessions and dialysis adequacy do actually improve parameters of QOL and if this is beneficial enough at the cost of taking additional dialysis sessions in a low income country like Bangladesh. Whether being diabetic influences QOL was also investigated. Methods: This cross-sectional study recruited 135 adults, who were on maintenance haemodialysis(MHD) for >3 months, from three dialysis centers in Dhaka from January to December, 2013. Patients with malignancy, dementia, and psychosis were excluded. Patients were interviewed once by the investigators to fill a validated Bangla version of the kidney disease quality of life short form questionnaire (KDQOL-SF-36 version 1.3) and calculate a QOL score. Results: Mean age, mean duration of chronic kidney disease (CKD) and MHD were 50±12 years, 4.9±5.1 years and 12±11.8 months respectively. Overall QOL score for the study sample was 50±17. Only 43(31.9%) patients received adequate hemodialysis (mean Kt/V=1.3) while the rest (with Kt/V<1.2) had achieved an average Kt/V of 0.8 (p<0.001). Duration of MHD, hemoglobin, serum albumin, and ferritin were not significantly different for those adequately dialysed, compared to the rest. Also no improvement in any QOL parameter was found in those with Kt/V>1.2 (adequate HD). However, when a comparison was made between those with 3 HD sessions/week (n=63, mean MHD duration 24±14 months) with patients receiving 2 HD sessions/week (n=72, mean MHD duration 8.4±11 months), the former group had lower “effect of kidney disease” scores (p=0.021), higher “quality of social interaction” scores (p=0.031) and lower “role emotion” scores (p=0.002). When diabetic patients (n=82, mean age 54±8 years, MHD duration 18.5±9.5 months) and non-diabetic subjects (n=53, aged 42±13 years, MHD duration of 25±16 months) were compared, “effects of kidney disease”, “cognitive function” and “quality of social interaction” scales were significantly higher in those having diabetes (with p<0.045, p<0.024 and p<0.022 respectively). Conclusion: Since achieving hemodialysis adequacy was not found to improve QOL scores, an additional dialysis session at extra cost every week may not be advisable for people of a low income country Birdem Med J 2019; 9(2): 138-146

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Section: Discussionsupporting

confidence: 56%

Dialysis Adequacy and Quality of Life in Diabetic and Non-diabetic Bangladeshi Patients on Maintenance Hemodialysis

et al. 2019

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“…Unlike other countries, the length of hospitalization in Iran increases every year after starting dialysis (18). Through modifying factors influencing hemodialysis adequacy, negative consequences, hospitalization length and treatment costs are greatly reduced, and also the quality of life in patients with hemodialysis will increase (16,19). Factors influencing hemodialysis adequacy are high flux filter, increased BFR, number of hemodialysis sessions, increased fluid flow rate and hemodialysis time (6,20,21).…”

Section: Introductionmentioning

confidence: 99%

How to increase dialysis adequacy; A randomized clinical trial

et al. 2019

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Introduction: Studies have shown when hemodialysis treatment is sufficiently effective, complications of uremic syndrome, additional treatment costs and hospitalization length are reduced. Several methods have been proposed to improve hemodialysis adequacy. Objectives: In this study, the effects of the synchronic use of the stepwise profile dialysis fluid flow rate with increased blood flow rate (BFR) were studied on hemodialysis adequacy. Patients and Methods: This is a cross-over clinical trial study conducted on 34 hemodialysis patients selected from a hemodialysis center of Qazvin University of Medical Sciences, Qazvin, Iran. The patients were randomly allocated into two groups (n= 17 patients in each group) in two sequences. In the first sequence, the subjects received four routine hemodialysis sessions in group one and four hemodialysis sessions with the stepwise profile of the fluid flow rate with increased BFR in group two. In the second sequence, the treatment methods were exchanged. Hemodialysis sessions were performed in both sequences, consecutively. Each session was at least three hours. Hemodialysis adequacy was measured using Kt/V software on the hemodialysis machines after each session. Results: The mean score of dialysis adequacy was 0.89 in the routine method and 1.26 in the profile with increased BFR. There was a statistically significant difference between the methods (t= -7.9, df = 33, P < 0.001). Conclusion: The results of the study suggest that the stepwise profile of the dialysis fluid flow rate with increased BFR should be used synchronously to improve hemodialysis adequacy.

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“…It has been shown that a low serum albumin level is associated with an increase in morbidity and mortality in patients with CKD [6]. In addition, albumin is an independent factor for the development of anemia in patients with end stage CKD [10,11]. It is important to study the relationship between anemia and QOL in patients with CKD in the absence of protein-energy deficiency.…”

Section: N Owadays There Is a Dramatic Growth Of Population Of End-stmentioning

confidence: 99%

Influence of anemia on quality of life in patients with chronic kidney disease on renal replacement therapy

Evgenievna¹,

Vladimirovna²,

Vladimirovich³

et al. 2018

Medical news of the North Caucasus

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The influence of anemia and renal replacement therapy (RRT) on the quality of life (QOL) of patients with chronic kidney diseases (CKD) on HD, CAPD and kidney transplant recipients has been studied. 60 patients with CKD 5 were included in the study. Patients with CKD 3 were included in control group. It was found that the scores of QOL in the group of kidney transplant recipients were comparable with the scores in the group with CKD 3, and were better than in dialysis patients, not only in terms of physical health (PF and PCH), but also in the terms of the psychological component of health (VT and SF). Reliable (p<0.05) positive correlation have been obtained between QOL and hemoglobin levels (

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Relationship between anemia, quality of life, and laboratory indices in hemodialysis patients

Cited by 9 publications

References 2 publications

Dialysis Adequacy and Quality of Life in Diabetic and Non-diabetic Bangladeshi Patients on Maintenance Hemodialysis

Dialysis Adequacy and Quality of Life in Diabetic and Non-diabetic Bangladeshi Patients on Maintenance Hemodialysis

How to increase dialysis adequacy; A randomized clinical trial

Influence of anemia on quality of life in patients with chronic kidney disease on renal replacement therapy

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