Relationship between altered small intestinal motility and absorption after abdominal aortic aneurysm repair

Abstract

Whilst disruption in SI motility and flow (impedance) events was associated with reduced absorption of both lipid and carbohydrate, lipid malabsorption was more prolonged. This may reflect inadequate mixing of chyme from altered motility, so varying the nutrient composition of enteral feed may improve absorption in these patients.

Nutrition support in the critically ill

“…Although absorption of both lipid and glucose were impaired immediately after the surgical repair of an abdominal aortic aneurysm, which was associated with disruption of small intestinal motility [43], the lipid malabsorption persisted even when glucose absorption and intestinal motor function had normalized. Although absorption of both lipid and glucose were impaired immediately after the surgical repair of an abdominal aortic aneurysm, which was associated with disruption of small intestinal motility [43], the lipid malabsorption persisted even when glucose absorption and intestinal motor function had normalized.…”

Year in review in Intensive Care Medicine 2011: I. Nephrology, epidemiology, nutrition and therapeutics, neurology, ethical and legal issues, experimentals

“…Nguyen et al . [34] have investigated the absorption of fat and carbohydrates in the small intestine in relation to motility following surgical repair of abdominal aortic aneurysms. Motility was impaired as compared to controls.…”

Sucrose Malabsorption and Impaired Mucosal Integrity in Enterally Fed Critically Ill Patients

“…Small intestinal motility was not measured in this study; however, our group has previously shown the detrimental effects of critical illness on gastrointestinal motility and luminal flow (30)(31)(32). These findings suggest that factors such as reduced activity of sucrase, inadequate nutrient exposure to the luminal mucosa due to alterations in small intestinal motility or morphology, and reduced uptake in portal blood due to reduced mesenteric flow may play an important role in the absorption and metabolism of sucrose during critical illness.…”

“…We have previously demonstrated impaired absorption of glucose (9,29,30, 35) (a monosaccharide) and triglycéride (30). We have previously demonstrated impaired absorption of glucose (9,29,30, 35) (a monosaccharide) and triglycéride (30).…”