Relation of high-density lipoprotein cholesterol and triglycerides to incidence of atherosclerotic coronary artery disease (the PROCAM experience)

Integrated effects of the vasodilating beta-blocker nebivolol on exercise performance, energy metabolism, cardiovascular and neurohormonal parameters in physically active patients with arterial hypertension

“…29,30 The effects of antihypertensive therapy on the lipid and carbohydrate metabolism are relevant for long-term prognosis. 31 Nebivolol treatment did not alter the metabolic profile at rest or during exercise in a clinically relevant way. The modest decrease in HDL-cholesterol was compensated by the unaltered LDL/HDL quotient.…”

A point mutant of apolipoprotein A-I, V156K, exhibited potent anti-oxidant and anti-atherosclerotic activity in hypercholesterolemic C57BL/6 mice

“…The lesion was almost undetectable in the V156K-rHDL and R173C-rHDL injected groups, as compared with the other rHDL-injected groups. Schulte, 1992), although the exact mechanism underlying HDL's anti-atherogenic potential remains uncertain. One of the widely-accepted explanations is that inhibitory activity against LDL oxidation is a firmly established virtue of HDL, representing a potent anti-atherogenic factor.…”

Relationship between HDL-Cholesterol and Angiographic Severity of Coronary Artery Disease

“…17 In angiographic studies the relation between HDL-C levels and CAD has varied widely ranging from significant inverse correlation with HDL-C and were the only significant predictor of the number of lesions. 18 …”