Relation between Sympathetic Overactivity and Left Atrial Spontaneous Echo Contrast in Patients with Mitral Stenosis and Sinus Rhythm

Özdemir, Özcan; Alyan, Ömer; Soylu, Mustafa; Topaloğlu, Serkan; Aras, Dursun; Metin, Fatma; Geyık, Bilal; Özbakır, Cemal; Demir, Ahmet Duran

doi:10.1016/j.hlc.2006.03.009

Cited by 4 publications

(5 citation statements)

References 40 publications

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“…2 ). LF was used as a marker of sympathetic activity 8 . The highest values of LF power were in the group of protocol 2, which indicated vagal inhibition.…”

Section: Resultsmentioning

confidence: 99%

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The effects of anesthetic drug choice on heart rate variability and echocardiography parameters in cats

Panprom,

Pattanapon,

Petchdee

2024

Sci Rep

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Heart rate variability (HRV) is one of the assessments of cardiovascular risk during general anesthesia. This study aimed to assess the effects of an anesthetic drug on HRV in cats and to provide information for clinical applications. Twenty-four healthy client-owned cats of various breeds, 12 females and 12 males scheduled for elective surgery, were enrolled in this study. The cats were premedicated and induced with 4 protocols: protocol 1, diazepam (0.3 mg/kg) and propofol (2–4 mg/kg) IV; protocol 2, diazepam (0.3 mg/kg) and alfaxalone (1–3 mg/kg) IV; protocol 3, diazepam (0.3 mg/kg) and ketamine (3–5 mg/kg) IV; and protocol 4, xylazine (1 mg/kg) and tiletamine/zolazepam (Zoletil) (5 mg/kg) IM. The heart rate and HRV of the 24 cats were collected before and at least 1 h after administering the anesthetic drugs. Echocardiography was performed to evaluate heart function. Oscillometric blood pressure monitoring was used to obtain the mean blood pressure. After anesthetic drug administration, higher heart rates were found in cats premedicated and induced with alfaxalone (p = 0.045) than in the other protocols. The lowest heart rate (HR) values were found in cats in protocol 4 using xylazine and Zoletil. The HRV low frequency (LF) and high frequency (HF) power ratios increased in all protocols except for cats premedicated and intubated with propofol. The standard deviation of the regular sinus beats (SDNN) was higher in cats premedicated and induced with ketamine than in other anesthetic protocols (p = 0.015). An increase in sympathetic activity and reduced HRV is associated with high blood pressure and left atrial dimension. The percentage of fractional shortening (FS) decreased in cats premedicated with ketamine. The results showed that the anesthesia method using diazepam and propofol caused the least disturbance of HRV compared with other anesthesia methods that were used in this study.

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“…2 ). LF was used as a marker of sympathetic activity 8 . The highest values of LF power were in the group of protocol 2, which indicated vagal inhibition.…”

Section: Resultsmentioning

confidence: 99%

“…The frequency domain or spectral analysis is measured by transforming ECG signals into spectral signals. A previous study showed that the progression of cardiac conditions could alter cardiac autonomic activity, which leads to an increase in heart rate and a decrease in HRV 7 , 8 .…”

Section: Introductionmentioning

confidence: 99%

The effects of anesthetic drug choice on heart rate variability and echocardiography parameters in cats

Panprom,

Pattanapon,

Petchdee

2024

Sci Rep

View full text Add to dashboard Cite

show abstract

“…2). LF was used as a marker of sympathetic activity 17 . The highest values of the LF power were in the group of protocol 2 which indicated a vagal inhibition.…”

Section: Resultsmentioning

confidence: 99%

The effects of anesthetic drug choice on heart rate variability and echocardiography parameters in cats

Panprom

Pattanapon

Petchdee

2023

Preprint

View full text Add to dashboard Cite

Heart rate variability is one of the assessments for cardiovascular risk during general anesthesia. The aims of this study were to assess the effects of an anesthetic drug on heart rate and heart rate variability (HRV) in cats and to provide the information for clinical applications. Twenty-four healthy client-owned cats of various breeds, 12 females and 12 males scheduled for elective surgery, were enrolled in this study. The cats were premedicated and induced with 4 protocols: protocol 1, diazepam (0.3 mg/kg) and propofol (3 mg/kg); protocol 2, diazepam (0.3 mg/kg) and alfaxalone (3 mg/kg); protocol 3, diazepam (0.3 mg/kg) and ketamine (5 mg/kg); and protocol 4, xylazine (1 mg/kg) and tiletamine/zolazepam (Zoletil) (5 mg/kg). The heart rate and heart rate variability of the 24 cats were collected before and at least 1 hour after administering the anesthetic drugs. Echocardiography was performed to evaluate heart function. Doppler was used to obtain the mean blood pressure. After anesthetic drug administration, higher heart rates were found in cats premedicated and induced with alfaxalone (p = 0.045) than in the other protocols, and the lowest heart rate (HR) values were found in cats in protocol 4 using xylazine and Zoletil. The HRV low frequency (LF) and high frequency (HF) power ratios increase in all protocols except for cats premedicated and intubation with propofol. The standard deviation of the normal sinus beats (SDNN) was higher in cats premedicated and induced with ketamine than in other anesthetic protocols (p = 0.015). An increase in sympathetic activity and reduced heart rate variability is associated with high blood pressure and left atrial dimension. The percentage of fractional shortening (FS) decreased in cats premedicated with ketamine. This study demonstrated that an anesthetic protocol using diazepam and propofol preserved cardiovascular function and was safe to use for surgeries in cats.

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“…The standard deviation of the R-R interval (SDNN) increased after anesthetic drug administration in almost all groups except for protocol 2 (alfaxalone), indicating a reduction in parasympathetic tone, which was related to the significant increase in the heart rate in this group (Figure 2). LF was used as a marker of sympathetic activity 18 . The highest values of LF power were in the group of protocol 2, which indicated vagal inhibition.…”

Section: Resultsmentioning

confidence: 99%

The effects of anesthetic drug choice on heart rate variability and echocardiography parameters in cats

Panprom,

Pattanapon,

Petchdee

2023

Preprint

View full text Add to dashboard Cite

Heart rate variability (HRV) is one of the assessments of cardiovascular risk during general anesthesia. This study aimed to assess the effects of an anesthetic drug on HRV in cats and to provide information for clinical applications. Twenty-four healthy client-owned cats of various breeds, 12 females and 12 males scheduled for elective surgery, were enrolled in this study. The cats were premedicated and induced with 4 protocols: protocol 1, diazepam (0.3 mg/kg) and propofol (2-4 mg/kg); protocol 2, diazepam (0.3 mg/kg) and alfaxalone (1-3 mg/kg); protocol 3, diazepam (0.3 mg/kg) and ketamine (3-5 mg/kg); and protocol 4, xylazine (1 mg/kg) and tiletamine/zolazepam (Zoletil) (5 mg/kg). The heart rate and HRV of the 24 cats were collected before and at least 1 hour after administering the anesthetic drugs. Echocardiography was performed to evaluate heart function. Doppler was used to obtain the mean blood pressure. After anesthetic drug administration, higher heart rates were found in cats premedicated and induced with alfaxalone (p = 0.045) than in the other protocols. The lowest heart rate (HR) values were found in cats in protocol 4 using xylazine and Zoletil. The HRV low frequency (LF) and high frequency (HF) power ratios increased in all protocols except for cats premedicated and intubated with propofol. The standard deviation of the regular sinus beats (SDNN) was higher in cats premedicated and induced with ketamine than in other anesthetic protocols (p=0.015). An increase in sympathetic activity and reduced heart rate variability is associated with high blood pressure and left atrial dimension. The percentage of fractional shortening (FS) decreased in cats premedicated with ketamine. The results showed that the anesthesia method using diazepam and propofol was more effective in maintaining cardiovascular function than other anesthesia methods that were used in this study.

show abstract

Relation between Sympathetic Overactivity and Left Atrial Spontaneous Echo Contrast in Patients with Mitral Stenosis and Sinus Rhythm

Cited by 4 publications

References 40 publications

The effects of anesthetic drug choice on heart rate variability and echocardiography parameters in cats

The effects of anesthetic drug choice on heart rate variability and echocardiography parameters in cats

The effects of anesthetic drug choice on heart rate variability and echocardiography parameters in cats

The effects of anesthetic drug choice on heart rate variability and echocardiography parameters in cats

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