Relation Between Implant Position and Perceptual Threshold in a Patient with Epiretinal Prosthesis System

Tran, Bao Khanh; Wolfensberger, Thomas J.

doi:10.1055/s-0041-111749

Cited by 2 publications

(3 citation statements)

References 8 publications

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“…Although the implant stayed perfectly in place anatomically, our patient showed a slow reduction of the implantʼs sensitivity (higher perceptual threshold) over the time course of 16 months. As discussed earlier [3], many factors intervene in the process of an electrical stimulation delivered by an electrode to an action potential leading to visual perception. Additionally to factors such as anatomical, electrical, biological, physiological and psychological, we can now add the time factor as an important variable.…”

Section: Discussionmentioning

confidence: 99%

“…Additionally to factors such as anatomical, electrical, biological, physiological and psychological, we can now add the time factor as an important variable. Retinal thickness under the implant has been shown to change over time [3,4] and it is thought to have an impact on the physiological reaction of the retinal tissue to electrical stimulation. At this point of the clinical use of these implants, it is impossible to predict nor to ensure how an implant will interact with the retina over a long time.…”

Section: Discussionmentioning

confidence: 99%

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Retina-Implant Interaction after 16 Months Follow-up in a Patient with an Argus II Prosthesis

Tran

Wolfensberger

2017

Klin Monatsbl Augenheilkd

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Retina-Implant Interaction after 16 Months Follow-up in a Patient with an Argus II Prosthesis

Tran

Wolfensberger

2017

Klin Monatsbl Augenheilkd

Self Cite

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“…Therefore, reports of early surgical and clinical experience, including adapted surgical techniques with this pioneering strategy,26–29 should contribute to optimize implantation procedures for Argus II and other forthcoming retinal prosthetic devices. We believe that sharing the lessons learned from initial cases with the growing number of vitreoretinal surgeons who will be implanting these devices, may improve patient safety.…”

Section: Discussionmentioning

confidence: 99%

Argus II retinal prosthesis implantation with scleral flap and autogenous temporalis fascia as alternative patch graft material: a 4-year follow-up

Matet¹,

Amar²,

Mohand‐Saïd³

et al. 2016

OPTH

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IntroductionThe Argus II retinal prosthesis is composed of an epiretinal electrode array positioned over the macula and connected to an extrascleral electronics case via a silicone cable, running through a sclerotomy. During implantation, the manufacturer recommends to cover the sclerotomy site with a patch of processed human pericardium to prevent postoperative hypotony and conjunctival erosion by the underlying electronics case. Due to biomedical regulations prohibiting the use of this material in France, we developed an alternative technique combining a scleral flap protecting the sclerotomy and an autogenous graft of superior temporalis fascia overlying the electronics case.MethodsThe purpose of this study is to describe the 4-year outcomes of this modified procedure in three subjects who underwent Argus II Retinal Prosthesis System implantation. Clinical data consisting of intraocular pressure measurements and tolerance in terms of conjunctival erosion or inflammation were retrospectively assessed over a 4-year postoperative follow-up.ResultsNone of the three patients implanted with the modified technique developed ocular hypotony over 4 years. A normal, transient conjunctival inflammation occurred during the first postoperative month but conjunctival erosion was not observed in any of the three patients over 4 years. Four years after implantation, the autogenous temporalis fascia graft remained well tolerated and the retinal prosthesis was functional in all three patients.ConclusionThe combination of an autograft of superficial temporalis fascia and a scleral flap efficiently prevented leakage through the sclerotomy site, ocular hypotony, and conjunctival erosion by the extrascleral electronics case. This modified technique is suitable for the implantation of existing and forthcoming retinal prostheses. Superficial temporalis fascia may also be used as alternative to commercial tectonic tissues for scleral wound repair in clinical settings where they are not available.

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Relation Between Implant Position and Perceptual Threshold in a Patient with Epiretinal Prosthesis System

Cited by 2 publications

References 8 publications

Retina-Implant Interaction after 16 Months Follow-up in a Patient with an Argus II Prosthesis

Retina-Implant Interaction after 16 Months Follow-up in a Patient with an Argus II Prosthesis

Argus II retinal prosthesis implantation with scleral flap and autogenous temporalis fascia as alternative patch graft material: a 4-year follow-up

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