Relation between ectopic ossification after total hip arthroplasty and activity of general inflammation in patients with ankylosing spondylitis

Tani, Yasuhiro; Nishioka, Junichi; Inoue, Koji; Hukuda, Sinsuke; Tsujimoto, Masaki

doi:10.1136/ard.57.10.634

Cited by 9 publications

(4 citation statements)

References 6 publications

(2 reference statements)

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“…The retrospective survey of Sundaram did not find any relation between elevated preoperative ESR and HO after THA in ankylosing spondylitis [13]. However, Tani et al reported that elevated preoperative CRP values were significantly associated with the formation of HO after THA in AS [45]. Consistent with this, our study showed a positive relation between the formation of HO and the preoperative elevated ESR and CRP values.…”

Section: Discussionsupporting

confidence: 92%

Risk Factors of Heterotopic Ossification Following Total Hip Arthroplasty in Patients With Ankylosing Spondylitis

Thilak

Panakkal

Kim

et al. 2015

The Journal of Arthroplasty

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Section: Discussionsupporting

confidence: 92%

Risk Factors of Heterotopic Ossification Following Total Hip Arthroplasty in Patients With Ankylosing Spondylitis

Thilak

Panakkal

Kim

et al. 2015

The Journal of Arthroplasty

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“…HO was recorded in 30 % of a group of AS patients (n = 20), and it was associated with high level of CRP [31]. As treatment, randomized, controlled studies support the non-steroidal anti-inflammatory agents (NSAIDs), mainly indomethacin and radiation, even if the result obtained are not convincing [22,[41][42][43][44][45][46][47].…”

Section: Surgical Managementmentioning

confidence: 99%

Rehabilitation and surgical management of ankylosing spondylitis

et al. 2013

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Ankylosing spondylitis (AS) is a chronic inflammatory disease which, if untreated, may progress to severe damage of the spine with functional impairment, disability and poor quality of life. An increased mortality has been reported in AS patients compared to the general population. AS requires combined management (pharmacological and non-pharmacological) and advice by different health professionals. Even the pharmacological treatment in the last decade has dramatically changed the outcome, the severity of the disease might require a surgical approach for the hip involvement with total hip replacement, or the corrective spinal surgery. However, this surgery deserves some careful approaches since the complexity of the disease. Rehabilitation still represents a cornerstone of the global management of AS patients. The present review summarizes the state of art of surgical management of these two diseases

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“…Patients with AS considered at risk are those who need repeat surgery, develop postoperative infection, undergo a trans-trochanteric approach, or have concurrent active disease 11, 15 . One study of 20 AS patients found HO to occur in 30%, and correlated with C-reactive protein levels 27 . Randomized, controlled studies support nonsteroidal anti-inflammatory agents (NSAID), most often indomethacin, and radiation as efficacious for prophylaxis, but yield inconsistent results 28, 29 .…”

Section: Surgical Considerationsmentioning

confidence: 99%

Physical Therapy and Surgery

Valle-Oñate

Ward

Kerr

et al. 2012

The American Journal of the Medical Sciences

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Physical therapy and orthopedic surgery are important components in the treatment of ankylosing spondylitis (AS). Supervised physical therapy is more effective that individual or unsupervised exercise in improving symptoms, but controlled trials suggest than combined inpatient and outpatient therapy provides the greatest improvement. Recommendations for exercise are universal, but the best types and sequence of therapies are not known. Total hip replacement is the surgery most commonly performed for AS, with good long-term implant survival. Heterotopic ossification may occur no more frequently after hip replacement in patients with AS than in patients with other diseases. Corrective spinal surgery is rarely performed and requires specialized centers and experienced surgeons.

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Relation between ectopic ossification after total hip arthroplasty and activity of general inflammation in patients with ankylosing spondylitis

Cited by 9 publications

References 6 publications

Risk Factors of Heterotopic Ossification Following Total Hip Arthroplasty in Patients With Ankylosing Spondylitis

Risk Factors of Heterotopic Ossification Following Total Hip Arthroplasty in Patients With Ankylosing Spondylitis

Rehabilitation and surgical management of ankylosing spondylitis

Physical Therapy and Surgery

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