Reinvestigation of Mucohalic Acids: Recent Development and Application in Drug Discovery

Abstract

The recent synthetic development and applications of mucochloric acid, mucobromic acid and their derivatives are described, mainly focus on our work using these multiple functional molecules to access a wide variety of γ-butenolides, γ-lactams, 4,5-dihalopyridazin-3-ones and other novel, multi-functionalized building blocks and pharmaceutical products.