Regulators of protein metabolism are affected by cyclical nutritional treatments with diets varying in protein and energy content

Ezzine, Sourour Boussaid-Om; Métayer-Coustard, Sonia; Collin, Anne; Rideau, Nicole; Leterrier, Christine; Bouvarel, Isabelle; Seiliez, Iban; Tesseraud, Sophie

doi:10.1016/j.jnutbio.2011.09.009

Cited by 3 publications

(2 citation statements)

References 46 publications

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“…Of the feeding behavior variables studied, meal frequency has been identified as having a potential influence on body composition ( O’hea and Leveille, 1969 ) as shown in mice that achieved a significant fat loss without lean loss when intermittently fasted ( Gotthardt et al, 2016 ). Likewise, intermittent feed restriction through sequential feeding in poultry led to a quick adjustment in lipogenesis and protein synthesis ( Ezzine et al, 2012 ). In the same study, a pulse feeding of protein increased the nitrogen balance compared to ad libitum feeding.…”

Section: Introductionmentioning

confidence: 99%

Feeding behavior of growing and finishing pigs fed different dietary threonine levels in a group-phase feeding and individual precision feeding system

Remus

Hauschild

Létourneau-Montminy

et al. 2020

Translational Animal Science

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Feeding behavior is an important aspect of pig husbandry, as it can affect protein deposition in pigs. A decrease in plasma threonine (Thr) levels may influence feed intake due to amino acid (AA) imbalance. We set out to study whether different Thr inclusion rates of 70%, 85%, 100%, 115% and 130% of the ideal Thr:lysine (Lys) ratio of 0.65 in two different feeding programs (individual precision feeding (IPF) and group phase feeding (GPF)) could affect pig feeding behavior and consequently protein deposition. Two 21-day trials were performed in a 2×5 factorial setup (feeding systems × Thr levels) with 110 pigs in growing phase (25.0 ± 0.8 kg of body weight (BW)) and 110 pigs in finishing phase (110.0 ± 7.0 kg BW), which correspond to 11 pigs per treatment in each trial. Pigs were housed in the same room and fed using computerized feeding stations. The total lean content was estimated by dual X-ray absorptiometry at the beginning (d 1) and the end (d 21) of the trial. Multivariate exploratory factor analysis was performed to identify related variables. Confirmatory analysis was performed by orthogonal contrasts and Pearson correlation analysis. Graphical analysis showed no difference in feeding patterns between feeding systems during the growing or finishing phase. Pigs exhibited a predominant diurnal feeding, with most meals (73% on average) consumed between 0600 h and 1800 h. Exploratory factor analysis indicated that feeding behavior was not related to growth performance or protein deposition in growing or finishing pigs. Changes in feeding behavior were observed during the growing phase, where increasing dietary Thr resulted in a linear increase in the feed intake rate (P < 0.05). During the finishing phase, the duration of the meal and feed intake rate increased linearly as dietary Thr increased in the diet (P < 0.05). These changes in feeding behavior are, however, correlated to body weight (BW). In conclusion, the exploratory factor analysis indicated that feeding behavior had no correlation with growth performance or protein and lipid deposition in growing or finishing pigs. Dietary Thr levels and feeding systems had no direct effect on feed intake.

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Section: Introductionmentioning

confidence: 99%

Feeding behavior of growing and finishing pigs fed different dietary threonine levels in a group-phase feeding and individual precision feeding system

Remus

Hauschild

Létourneau-Montminy

et al. 2020

Translational Animal Science

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“…Specifically, the mammalian target of rapamycin (mTOR) pathway is a key regulator of cell growth, which integrates signals from nutrients, energy status, and growth factors to regulate metabolism . Feeding regimens, amino acid abundance and availability, , protein abundance, and protein source are able to affect this pathway. Downstream targets of mTOR include eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1) and eukaryotic translation initiation factor 4E (eIF4E) that mediate steps in translation initiation and ribosomal protein S (S6) and ribosomal protein S6 kinase (S6K1) that are thought to regulate protein translation .…”

Section: Introductionmentioning

confidence: 99%

Nutritional and Metabolic Impacts of a Defatted Green Marine Microalgal (Desmodesmus sp.) Biomass in Diets for Weanling Pigs and Broiler Chickens

Ekmay

Gatrell

Lum

et al. 2014

J. Agric. Food Chem.

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Two experiments were conducted to determine the nutritional and metabolic impacts of defatted green microalgal (Desmodesmus sp.) biomass (DGM), protease, and nonstarch polysaccharide degrading enzymes (NSPase) in diets for weanling pigs and broiler chicks. Pigs fed 10% DGM for 28 days had growth performance comparable to the controls, but 23-39% lower (P < 0.05) plasma urea nitrogen concentrations. Broilers fed 15% DGM had 16% greater (P < 0.05) gain/feed efficiency than the control (0.78 vs 0.67) over the 42 day period. Supplemental protease (0.06%) decreased (P < 0.03) plasma uric acid concentrations in pigs on day 14, whereas supplemental NSPase showed negative effects in broilers. Dietary inclusions of DGM or enzymes altered (P < 0.05-0.1) hepatic and muscle protein levels of key regulators in the mTOR pathway. In conclusion, weanling pigs and broiler chicks tolerated dietary inclusions of 10 and 15% DGM, respectively, and adding protease might help digestion.

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Graded levels of a defatted green microalgae inclusion in diets for broiler chicks led to moderate up-regulation of protein synthesis pathway in the muscle and liver

et al. 2018

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Regulators of protein metabolism are affected by cyclical nutritional treatments with diets varying in protein and energy content

Cited by 3 publications

References 46 publications

Feeding behavior of growing and finishing pigs fed different dietary threonine levels in a group-phase feeding and individual precision feeding system

Feeding behavior of growing and finishing pigs fed different dietary threonine levels in a group-phase feeding and individual precision feeding system

Nutritional and Metabolic Impacts of a Defatted Green Marine Microalgal (Desmodesmus sp.) Biomass in Diets for Weanling Pigs and Broiler Chickens

Graded levels of a defatted green microalgae inclusion in diets for broiler chicks led to moderate up-regulation of protein synthesis pathway in the muscle and liver

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