Regulation of sodium and total body water metabolism in pregnancy

Serial Estimation of Plasma Renin Concentration During Pregnancy and After Parturition

“…The present findings lend some support to this view in that both the secretion (Jones, Lloyd Jones, Riondel, Tait, Tait, Bulbrook & Greenwood, 1959;Gray, Munro, Sims, Meeker, Solomon & Watanabe, 1964; and excretion (Martin & Mills, 1956;Venning & Dyrenfurth, 1956;Rinsler & Rigby, 1957) of aldosterone are also known to increase during pregnancy. As pointed out by Tait (1964), however, the increase in renin and aldosterone may not be parallel throughout pregnancy.…”

Blood Pressure Responses to Dietary Sodium Manipulation During Normotensive Human Pregnancy

“…The controversy will continue so long as the riddle of the 'disease of theories', pre-eclampsia or pregnancy associated hypertension (PAH), remains unsolved (Lindheimer & Katz 1983). Normal pregnancy is characterized by an increase in both sodium space and total body water (Gray & Plentl 1954;MacGillivray & Buchanan 1958;Gray et a/. 1964), and many investigators have speculated that sodium may play a facilitatory role in the development of PAH (Forrester & Alleyne 1980;Little 1965;Mengert & Tacchi 1961;Redd et al 1968).…”

Evaluation of the relationship of sodium in drinking water and toxemia of pregnancy.

“…In a recent study of a predominantly Black low-income pregnant population a mean daily unrestricted Na+ intake of less than 2,000 mg was determined by 24-hour diet recall.2' Another study found an average daily Na+ intake of 4,200 mg when free use of salt was allowed in a group of white, unmarried, pregnant women. 22 No comparable data for MexicanAmerican women could be located. We feel fairly safe in assuming an average intake of sodium from food in our study population to be about 4,000 mg/day or less.…”