Regulación de la respuesta inmune frente a la infección por Helicobacter pylori

P., Silvana Arenillas; F., Alex Godoy; F., Helly Einisman; P., Daniela García; D., Paul Harris

doi:10.4067/s0370-41062002000200002

Cited by 5 publications

(4 citation statements)

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“…Helicobacter pylori infection provokes an increase in some cytokines, therefore inducing chronic inflammation. 28 Infection with H. pylori could produce a systemic immuno-stimulation and subsequent growth retardation. 29 Infections may also decrease appetite and increase the nutritional requirements because of a catabolic phase relationship with the immune response.…”

Section: Discussionmentioning

confidence: 99%

Association of Helicobacter pylori Infection and Height of Mexican Children of Low Socioeconomic Level Attending Boarding Schools

Vilchis

Duque²,

Mera³

et al. 2009

The American Journal of Tropical Medicine and Hygiene

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Abstract. This study evaluated the association between Helicobacter pylori infection and height in a population of schoolchildren of a low socioeconomic level regarding growth-related micronutrient status. It was a cross-sectional study of 685 children 5-13 years of age. Height and weight were recorded, a 13 C urea breath test was performed for detection of H. pylori , and a blood sample was obtained for determination of micronutrient status. Helicobacter pylori infection was found to be associated with the height of children. Children with H. pylori infection are, on average, 1.32 cm lower (95% confidence interval [CI] = -2.22 to -0.42) in height than children without infection. There was an effect modification by age: for every one-year increase in age, height was 0.66 cm less (95% CI = -1.17 to -0.15) in children with H. pylori infection. This finding suggests that H. pylori infection has a negative effect on the growth of children.

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Section: Discussionmentioning

confidence: 99%

Association of Helicobacter pylori Infection and Height of Mexican Children of Low Socioeconomic Level Attending Boarding Schools

Vilchis

Duque²,

Mera³

et al. 2009

The American Journal of Tropical Medicine and Hygiene

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“…The objective of this study was to investigate the effect on the immune response in subjects infected with helminths, its possible relationship with gastric cancer or its progression from predecessor stages of the disease. It has been described that when infected with H. pylori bacterial antigens such as the B subunit of urease (36) are recognized by pattern recognition receptors that will initiate the immune response (37) this response is characterized by a process called immunological polarization ( 38) , which consists of processes that are performed for one of the two predominant types of lymphocytes helper 1 and 2 (Th1 and Th2) that come from the same precursor, the T lymphocyte naïve (Th0) is Diff and to one of the two lines predominantly , polarization occurs to the profile of cyto c inas to the display above, the most important are interleukin 12 (IL-12) and interleukin 10 (IL-10), if the cells Th0 are exposed s to high levels of IL-12 and Th1 differentiate directly inhib would production and development of Th2 cells, by secreting molecules as TIM-3 (37,39,40) with a response predominantly of T helper cells 1 ( Th1), which mediate the cellular immune response, favor tissue damage and inflammation through different mechanisms that include the production of molecules such as interferon gamma (INF-γ) and tumor necrosis factor alpha (TNF-α) ( 41) , these molecules cause the release of IL-8 in the epithelial cells of the gastric mucosa, which is a potent neutrophil chemotactic factor (41) , promote tissue damage and cause an increase in the expression of proteins of the major complex of histocompatibility (HCM) that could favor H.pylori infection (42) . This phenomenon also occurs when an individual is infected with intestinal helminths (43) , the intestinal epithelium cytosines released as the s interleukin s 10, 25 and 32 having function alarminas quickly initiate polarization towards Th2 and molecules as lymphopoietin stromal thymic which has a function similar to TIM-3 but suppressing the TH1 response (1.44) .…”

Section: Discussionmentioning

confidence: 99%

Relationship Between Helminthasis and Gastric Cancer: A Systematic Review

Moreno

2021

Preprint

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Introduction: helminths are parasitic worms able to produce diverse clinical manifestations in humans, mainly in the gut. Gastric cancer its a high incidence entity in Colombia, being the highland regions where its incidence is the highest in comparison with the lower incidence coastal region. From the above it is intended to determine the relationship between helminthiasis and the development of gastric cancer. Methodology: A systematic review was performed in four databases for studies evaluating the relationship between helminthiasis and the development of gastric cancer. Results: We included 16 articles from 929 records, with 11 articles reporting a positive relationship and 5 articles with negative relationship. Conclusions: Parasitic infections of the gastrointestinal tract by helminths promote TH-2 type immune responses and decrease TH-1 type that are involved in the progression of precancerous lesions associated with Helicobacter pylori infection. Keywords: Gastric cancer, Helminthiases, inflammation.

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“…In toothpastes, sodium fluoride ionizes to give fluoride ions, while sodium monofluorophosphate requires the action of salivary phosphatase enzyme to ionize. 22 Abrasives should be compatible with the fluoride compound used, as they have the ability to inactivate fluoride by binding to the ionized fluoride available and rendering it inactive. 17,18 Accordingly, it can be concluded that…”

Section: Introductionmentioning

confidence: 99%

Measuring Total and Ionized Fluoride Content in Toothpastes Used by Egyptian Children

Eissa,

Badran,

Elghazawy

2023

Ahram Canadian Dental Journal

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Background: As the prevalence of dental caries in Egypt is high, it is imperative that fluoride content in toothpastes be sufficient to prevent it. Aim:To measure total and ionized fluoride content in toothpastes most commonly used by Egyptian children. Methods:A cross-sectional descriptive study was carried out by conducting a pilot survey to determine the two most commonly used toothpastes by Egyptian children aged 2-6 years.Triplicates of each were purchased from different stores and emptied into sterile, labeled containers. An ion chromatography system with fluoride ion-specific electrode was utilized to measure total and ionized fluoride content in each of the triplicates. Results:According to the pilot study, FKB and SKS toothpastes were the two most commonly used in the Egyptian market. Total fluoride content in FKB was not declared on its box, and when measured was 878.23±26.76 ppm. Its ionized fluoride content was 648.87±47.93 ppm.Total fluoride concentration in SKS was declared to be 1000 ppm, and when measured was 896.73±25.12 ppm, while the ionized fluoride content was 686.07±68.53 ppm. Total and ionized mean released fluoride from both brands of toothpastes were all significantly lower than 1000 ppm (p<0.05), which is the fluoride concentration needed for caries prevention. Conclusion:Fluoride content in the examined toothpastes is not coincident with that declared by the manufacturer, and significantly lower than the concentration needed for caries prevention.More care and better monitoring of toothpastes in the Egyptian market are recommended.

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Regulación de la respuesta inmune frente a la infección por Helicobacter pylori

Cited by 5 publications

References 0 publications

Association of Helicobacter pylori Infection and Height of Mexican Children of Low Socioeconomic Level Attending Boarding Schools

Association of Helicobacter pylori Infection and Height of Mexican Children of Low Socioeconomic Level Attending Boarding Schools

Relationship Between Helminthasis and Gastric Cancer: A Systematic Review

Measuring Total and Ionized Fluoride Content in Toothpastes Used by Egyptian Children

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