Regional hemodynamics during postexercise hypotension. I. Splanchnic and renal circulations

Pricher, Mollie P.; Holowatz, Lacy A.; Williams, Jay T.; Lockwood, Jennifer M.; Halliwill, John R.

doi:10.1152/japplphysiol.00465.2004

Cited by 48 publications

(51 citation statements)

References 37 publications

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“…This underscores the possibility that systemic mechanisms, such as sympathetic decrease, opioid release, and thermoregulation, play a role. Since postexercise blood flow was measured in an inactive region and postexercise vasodilation is known to be more pronounced in exercised muscle (56), this response might have been even greater if the measurements had been taken on the leg.…”

Section: Discussionmentioning

confidence: 99%

Low-dose estrogen therapy does not change postexercise hypotension, sympathetic nerve activity reduction, and vasodilation in healthy postmenopausal women

Oneda

Forjaz²,

Bernardo³

et al. 2008

American Journal of Physiology-Heart and Circulatory Physiology

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The aim of this study was to determine whether estrogen therapy enhances postexercise muscle sympathetic nerve activity (MSNA) decrease and vasodilation, resulting in a greater postexercise hypotension. Eighteen postmenopausal women received oral estrogen therapy (ET; n ϭ 9, 1 mg/day) or placebo (n ϭ 9) for 6 mo. They then participated in one 45-min exercise session (cycle ergometer at 50% of oxygen uptake peak) and one 45-min control session (seated rest) in random order. Blood pressure (BP, oscillometry), heart rate (HR), MSNA (microneurography), forearm blood flow (FBF, plethysmography), and forearm vascular resistance (FVR) were measured 60 min later. FVR was calculated. Data were analyzed using a two-way ANOVA. Although postexercise physiological responses were unaltered, HR was significantly lower in the ET group than in the placebo group (59 Ϯ 2 vs. 71 Ϯ 2 beats/min, P Ͻ 0.01). In both groups, exercise produced significant decreases in systolic BP (145 Ϯ 3 vs. 154 Ϯ 3 mmHg, P ϭ 0.01), diastolic BP (71 Ϯ 3 vs. 75 Ϯ 2 mmHg, P ϭ 0.04), mean BP (89 Ϯ 2 vs. 93 Ϯ 2 mmHg, P ϭ 0.02), MSNA (29 Ϯ 2 vs. 35 Ϯ 1 bursts/min, P Ͻ 0.01), and FVR (33 Ϯ 4 vs. 55 Ϯ 10 units, P ϭ 0.01), whereas it increased FBF (2.7 Ϯ 0.4 vs. 1.6 Ϯ 0.2 ml ⅐ min Ϫ1 ⅐ 100 ml Ϫ1 , P ϭ 0.02) and did not change HR (64 Ϯ 2 vs. 65 Ϯ 2 beats/min, P ϭ 0.3). Although ET did not change postexercise BP, HR, MSNA, FBF, or FVR responses, it reduced absolute HR values at baseline and after exercise. postmenopause; aerobic exercise; muscle sympathetic nerve activity; blood pressure THE POSTMENOPAUSAL PERIOD is accompanied by a number of physiological alterations (49). In postmenopausal women, blood pressure gradually increases (71), resulting in a considerably higher incidence of hypertension than that seen in premenopausal women (68). This difference has been attributed to abnormalities in arteriolar resistance caused by the absence of estrogen (48) and/or by physiological aging (1). Arteriolar resistance and hypertension are usually associated with an increase in sympathetic activity or responsiveness (33,64). However, the effects of menopause on sympathetic activity remain unclear. One recent study evaluated Polish and American women between 40 and 56 yr of age (50). The authors found that sympathetic activity in the postmenopausal women was similar to that observed in the premenopausal women. In contrast, the authors of a study conducted in Japan (46) observed higher sympathetic nerve activity in post-and premenopausal middle-aged women. Discrepancies in results might be related to many factors, such as ethnic background and diet.Postmenopausal women are often treated with hormone replacement therapy to minimize the symptoms and consequences of menopause. However, the effects of this therapy depend on the type and dose of hormone employed (31). Currently, many women are receiving natural estrogens, and the North American Menopause Society recommends that hormone replacement therapy should be administered in low doses to avoid any possible side effects (...

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Section: Discussionmentioning

confidence: 99%

Low-dose estrogen therapy does not change postexercise hypotension, sympathetic nerve activity reduction, and vasodilation in healthy postmenopausal women

Oneda

Forjaz²,

Bernardo³

et al. 2008

American Journal of Physiology-Heart and Circulatory Physiology

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“…Franklin et al 57 observed that thermoregulation is another factor that could be associated with PEH. Nevertheless, a few studies suggest that thermoregulation 7 and splenic 58 , cutaneous 59 and cerebral 60 circulation contribute very little to PEH. Finally, another mechanism that might influence PEH is baroreflex function, which seems to increase after an exercise session 61,62 .…”

Section: Anunciação and Polito Post-exercise Hypotension In Hypertensivmentioning

confidence: 99%

Hipotensão pós-exercício em indivíduos hipertensos: uma revisão

Anunciação

Polito

2011

Arq. Bras. Cardiol.

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Post-exercise hypotension (PEH) may follow a session of physical exercises. This effect has high clinical relevance for hypertensive individuals. Although there are several studies on the subject, an analysis is still lacking on a state-of-art approach considering different types of exercises.Using a review of literature, the aim of this paper was to verify the relationship between aerobic exercise and resistance exercise in PEH in hypertensive people.For the purpose of this study, Scielo and Medline databases were surveyed, and the main inclusion criteria were studies on the subject in English language and a sample of hypertensive adults. One hundred and twenty-six studies were found. However, only 32 papers, 5 of which on resistance exercise and 27 on aerobic exercise were used for this study. Although the studies surveyed used different prescription models for resistance exercise, PEH was observed mainly in the laboratory setting. After aerobic exercise, it was noted that PEH occurred for longer periods. However, there are differences of opinion as to the best intensity and duration of the exercise to be prescribed. Therefore, in hypertensive individuals declines in arterial pressure following aerobic exercise are apparently greater than those observed with resistance exercise. Nevertheless, in order to achieve sounder conclusions, further studies on ambulatory blood pressure monitoring should be conducted.

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“…After exercise, blood pressure (BP) falls below pre-exercise levels (Brandao Rondon et al 2002;Forjaz et al 1998Forjaz et al , 2004Halliwill et al 1996;Hayes et al 2000;Jones et al 2007;Pescatello et al 2004a;Pricher et al 2004;Queiroz et al 2009;Raine et al 2001;Rezk et al 2006;Senitko et al 2002;Takahashi et al 2000). On the other hand, heart rate (HR) persists elevated for many minutes or hours after exercise (Dujic et al 2006;Forjaz et al 1998Forjaz et al , 2004Heffernan et al 2006;Kannankeril et al 2004;Mourot et al 2004;Parekh and Lee 2005;Queiroz et al 2009;Rezk et al 2006;Savin et al 1982;Seiler et al 2007).…”

Section: Introductionmentioning

confidence: 99%

Post-concurrent exercise hemodynamics and cardiac autonomic modulation

et al. 2011

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Concurrent training is recommended for health improvement, but its acute effects on cardiovascular function are not well established. This study analyzed hemodynamics and autonomic modulation after a single session of aerobic (A), resistance (R), and concurrent (A + R) exercises. Twenty healthy subjects randomly underwent four sessions: control (C:30 min of rest), aerobic (A:30 min, cycle ergometer, 75% of VO(2) peak), resistance (R:6 exercises, 3 sets, 20 repetitions, 50% of 1 RM), and concurrent (AR: A + R). Before and after the interventions, blood pressure (BP), heart rate (HR), cardiac output (CO), and HR variability were measured. Systolic BP decreased after all the exercises, and the greatest decreases were observed after the A and AR sessions (-13 ± 1 and -11 ± 1 mmHg, respectively, P < 0.05). Diastolic BP decreased similarly after all the exercises, and this decrease lasted longer after the A session. CO also decreased similarly after the exercises, while systemic vascular resistance increased after the R and AR sessions in the recovery period (+4.0 ± 1.7 and +6.3 ± 1.9 U, respectively, P < 0.05). Stroke volume decreased, while HR increased after the exercises, and the greatest responses were observed after the AR session (SV, A = -14.6 ± 3.6, R = -22.4 ± 3.5 and AR = -23.4 ± 2.4 ml; HR, A =+13 ± 2, R =+15 ± 2 vs. AR =+20 ± 2 bpm, P < 0.05). Cardiac sympathovagal balance increased after the exercises, and the greatest increase was observed after the AR session (A = +0.7 ± 0.8, R = +1.0 ± 0.8 vs. AR = +1.2 ± 0.8, P < 0.05). In conclusion, the association of aerobic and resistance exercises in the same training session did not potentiate post-exercise hypotension, and increased cardiac sympathetic activation during the recovery period.

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Regional hemodynamics during postexercise hypotension. I. Splanchnic and renal circulations

Cited by 48 publications

References 37 publications

Low-dose estrogen therapy does not change postexercise hypotension, sympathetic nerve activity reduction, and vasodilation in healthy postmenopausal women

Low-dose estrogen therapy does not change postexercise hypotension, sympathetic nerve activity reduction, and vasodilation in healthy postmenopausal women

Hipotensão pós-exercício em indivíduos hipertensos: uma revisão

Post-concurrent exercise hemodynamics and cardiac autonomic modulation

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