Regional distribution of all-cause mortality and coronary disease incidence in Turkey: findings of Turkish Adult Risk Factor survey 2010

Abstract

The high age-adjusted overall mortality in Turkey shows nonsignificant differences across geographic regions, whereas the age-adjusted CHD incidence is high in the Black Sea and Marmara regions.

Diagnosis and management of acute heart failure

“…Turkey is a country with a high cardiovascular mortality rate- and recent national statistics show that the population structure has turned to an ‘aged’ population (1). As a consequence, AHF has become one of the main reasons of admission to cardiology clinics.…”

HDL-ApoE Content Regulates the Displacement of Hepatic Lipase from Cell Surface Proteoglycans

“…HDL from female hypercholesterolemic patients showed a slight but not significant increase in apoE, compared with the normolipidemic female subjects, which appears consistent to earlier studies that showed a significant increase in plasma apoE levels in hyperlipidemic patients, as compared with normal subjects. [17][18][19] HDL-apoE concentration appears to regulate HL displacement by HDL. Decreases in HDL-apoE content are associated with an increased ability of HDL to displace HL from the cell surface.…”

“…In other studies, hyperlipidemic patients have been shown to have higher plasma apoE levels than normolipidemic subjects. [17][18][19] Immunoblots of nondenaturing gradient gels were used to determine whether HL was associated with isolated HDL samples from normolipidemic and hyperlipidemic patients. As shown in Figure 8A, female normolipidemic HDL samples contained endogenous HL, which was associated with an 11 nm, HDL 2 class of HDL ( Figure 8A).…”

“…15,16 It has been shown that women have lower plasma apoE levels than men 15,16 and that hyperlipidemic patients have higher amounts of plasma apoE than normolipidemic subjects. [17][18][19] Subjects with very high levels of plasma apoE have also been shown to be hypertriglyceridemic 17 and high levels of apoE can increase cardiovascular disease mortality, specifically in the older population. 20 In this study, we show that increasing apoE content of synthetic HDL directly inhibits HL displacement.…”

The Value of Lipoprotein(a) as a Risk Factor and Its Association With Major Risk Factors in High and Low-Risk Dyslipidemic Patients According to Framingham Risk Scoring

“…Koroner kalp hastalıkları (KKH), dünyada ve Türkiye'de mortalite sıralamasında birinci sıradadır 1,2 . Koroner kalp hastalığı ve inmeden oluşan kardiyovasküler hastalıklar (KVH)'dan birincil korunma önlemlerinin, hangi hastada, ne zaman başlatılması gerektiğine dair çalışmalar "risk faktörü" terimini ortaya çıkarmıştır.…”