Region-selective Metalization of Poly(methylmethacrylate) Surface Based on UV/ozone Surface Modification

胡贤巧,; 蒋艳,; 何巧红,; 施秧梦,; 胡辰辰,; 陈恒武,

doi:10.6023/a12070466

Cited by 3 publications

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References 2 publications

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“…与等离子体表面处理相比较, 紫外光表面处理技术除具有设备简单、操作方便等特点外, 其最大的优势在于配合掩膜的使用可以方便地实现区域化改性 [7] . 目前, 还未见利用紫外光表面改性和硅烷化技术实现热塑性高聚物与 PDMS 不可逆封合、并应用于制备复合微流控芯片的报道.…”

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An Approach for Irreversible Bonding of PDMS-PS Hybrid Microfluidic Chips at Room Temperature

Hu¹,

He²,

Bai³

et al. 2013

Acta Chim. Sinica

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In some circumstances, hybrid polymer microfluidic chips composed of both elastic, gas-permeable polydimethylsiloxane (PDMS) and rigid plastics are needed. However, it is quite difficult to bond PDMS irreversibly to plastics such as polystyrene (PS). In this article, a facile method for irreversible bonding of PDMS to PS was proposed based on UV/O 3 -assisted surface modification in combination of surface silanization. Firstly, a PS sheet was exposed to UV/O 3 to produce oxygen-containing polar moieties, such as hydroxyl and carboxylic acid, on its surface. Secondly, the UV/O 3 treated PS sheet was silanized with (3-aminopropyl)triethoxysilane (APTES) via the reaction between the oxygen-containing polar moieties on the PS surface and the molecules of APTES. Thirdly, the silanized-PS sheet and the PDMS substrate with micro channel network were treated with UV/O 3 again to generate silanol moieties on both surfaces. Finally, the UV/O 3 treated PDMS was immediately brought intimate contact with the UV/O 3 treated silanized-PS, and irreversible bonding of PDMS with PS occurred after putting the PDMS-PS complex at room temperature for 1 h through the condensation reaction between silanol moieties. Contact angle measurement, X-ray photoelectron spectroscopy, total reflection Fourier transformation infrared spectrometer were applied to characterize the surface chemistry of the PS during the UV/O 3 treatment and silanization. The hybrid PDMS-PS microfludic chips prepared with the established method can bear a gas pressure higher than 0.5 MPa and a water stream at a flow rate higher than 170 µL/min (the test channels were 2.5 cm in the length, 50 µm in the width, 200 µm in the depth). A hybrid PDMS-PS microfluidic chip composed of gas-permeable PDMS substrate with channel network and excellently biocompatible PS cover sheet was fabricated for cell culture. The experimental results showed that HeLa cells cultured in the hybrid PDMS-PS microchip grew much better than those cultured in the full PS microchip, and slightly better than those in the full PDMS microchip.

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