Regimes of Multiple Emulsions of W1/O/W2 and O1/W/O2 Type in the Continuous Couette‐Taylor Flow Contactor

Dłuska, E.; Markowska-Radomska, Agnieszka

doi:10.1002/ceat.200900278

Cited by 21 publications

(15 citation statements)

References 19 publications

(19 reference statements)

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“…It is worth noting that because of its interesting feature, Couette-Taylor flow has been studied by many researchers. Let us name only a few recently published examples: biotechnology Zhu et al (2010); multiple emulsion preparation Dluska and Markowska-Radomska (2010), liquid-solid flow Saomoto et al (2010);and precipitation Jung et al (2010). Couette-Taylor flow takes place between two coaxial cylinders with the inner one rotating (rotor).…”

Section: Introductionmentioning

confidence: 99%

Starch gelatinisation in Couette-Taylor flow apparatus

Hubacz¹,

Buczyńska²

2011

Chemical and Process Engineering

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In this paper starch gelatinisation in Couette-Taylor flow (CTF) apparatus (equipped with a water heat jacket) has been investigated. CTF (characterised by the presence of Taylor vortices) provides good environment for gelatinisation, e.g. effective mixing, fast heat transfer, positive influence on starch rheological properties. During experiments starch gelatinisation degree and starch swelling has been studied. It was accompanied by temperature measurements performed along the apparatus. Additionally, starch gelatinisation was investigated by computer simulation. A complete starch gelatinisation was obtained for the shortest investigated residence time in the apparatus when the temperature in the heat jacket was above 85 °C. Nevertheless, it seems that it is still possible to reduce a residence time value, as well as, the value of T hj , but it may require some acceleration of rotor rotation. The swelling degree of gelatinised starch increased with growing values of residence time, rotor rotation and process temperature. Heat transferred could be affected by the structure of the Taylor vortex flow. No significant destruction of starch granules was observed during the treatment in Couette-Taylor flow apparatus. A quite satisfactory agreement between computer simulation and experiments results was achieved.

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Section: Introductionmentioning

confidence: 99%

Starch gelatinisation in Couette-Taylor flow apparatus

Hubacz¹,

Buczyńska²

2011

Chemical and Process Engineering

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“…In accordance with the prediction of the release kinetics from multiple emulsions, we propose and adapt the theoretical model of the mass transfer in the multiple emulsions system [10] combined with a novel one-step preparation method of multiple emulsions [11,12]. This study also extends analysis to gelled emulsion particles obtained from multiple emulsions [11] and other product structures such as micro-or nanoparticles.…”

Section: Introductionmentioning

confidence: 88%

“…The gelled emulsion particles were obtained after emulsification and the cross-linking process in the CTF contactor via multiple emulsion thermal hardening. The details of a novel one-step multiple emulsions preparation technique in the CTF contactor and micro-encapsulation procedure for gelled emulsion particle fabricate were discussed in our earlier publications [11,12]. Briefly, to prepare multiple emulsions, the membrane and internal liquid phases were introduced into the annular gap between the coaxial cylinders of the CTF contactor at the inlet cross section, followed by the external phase.…”

Section: Preparation Methods Of O 1 /W/o 2 Emulsions and Gelled Emulsimentioning

confidence: 99%

A Mathematical Model for Predicting Release Rate from Multiple Emulsions and Micro/Nanospheres

Dłuska

Markowska-Radomska

2010

Chem Eng & Technol

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This paper presents mass transfer models of the release process from hierarchical dispersed systems such as multiple emulsions and micro/nanospheres. The models were validated by experimental data of an active component released from multiple emulsions and microspheres obtained via multiple emulsion thermal cross-linking. The simulations of release profiles confirmed the importance of the internal structure of multiple emulsions/microspheres, as well as the intensity of external mixing in the modeling of the controlled release process. The models presented allowed the mass released to be determined within satisfactory agreement with experimental data after optimization of parameters that describe internal emulsion/microsphere structure. The model proposed for describing the release process from microspheres can simulate release profiles that exhibit phasic behavior (primary/lag and continuous release). The model simulations were extended to nanoscale particles with satisfactory results.

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“…The method of multiple (double) emulsions formation via the one-step method in the Couette-Taylor flow contactor involves mixing internal water phase with membrane oil phase at the inlet cross section of contactor where simple emulsions are created and then introducing the external water phase to formulate multiple emulsions. The method has beeen described more precisely in our previous papers [10], [11].…”

Section: B Methods Of Formation Of the W 1 /O/w 2 Multiple Emulsionmentioning

confidence: 99%

Functionalized Multiple Emulsions as Platforms for Targeted Drug Delivery

Metera¹,

Dłuska²,

Markowska-Radomska³

et al. 2017

IJCEA

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Abstract-The paper presents the results of modification of outer interfaces of oil drops of multiple emulsions W 1 /O/W 2 for targeted drug delivery. The modification involves physical adsorption of antibodies: anti-CD15 (Hodgkin's disease marker). The effect of molecular interaction between molecules of antibody (protein) and oil phase compounds was measured using isothermal titration calorimetry (ITC). The ITC analysis also included investigation of interactions between components of emulsion and antibody buffer. Multiple emulsions were prepared by a one-step method, in a bioreactor with the Couette-Taylor flow. The inner phase of the emulsion was an aqueous solution of alginic acid, membrane phase was soybean oil, the outer phase was distilled water, appropriate surfactants were added to each phase. The influence of the structure of multiple emulsions (double emulsions with single internal drops and many internal drops) on adsorption of antibodies was investigated. The ITC analysis showed that antibodies interacted with emulsion compounds. The change in heat rates of molecular interactions suggested adhesion of protein onto oil drops interfaces.

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Regimes of Multiple Emulsions of W₁/O/W₂ and O₁/W/O₂ Type in the Continuous Couette‐Taylor Flow Contactor

Cited by 21 publications

References 19 publications

Starch gelatinisation in Couette-Taylor flow apparatus

Starch gelatinisation in Couette-Taylor flow apparatus

A Mathematical Model for Predicting Release Rate from Multiple Emulsions and Micro/Nanospheres

Functionalized Multiple Emulsions as Platforms for Targeted Drug Delivery

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