Regenerationspotenz der Knochenlosen Extremit�t

Liosner, L. D.; Woronzowa, M. A.; Kusmina, N. A.

doi:10.1007/bf00576070

Cited by 5 publications

(1 citation statement)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The scope of their scientific interest within the field of animal regeneration was extremely diverse. Initially, the model choice was confined to limb regeneration in amphibians, with the main focus on the balance of destruction and proliferation and the role of mitogenic radiation in these processes; a series of such studies was published in the Wilhelm Roux' Archiv für Entwicklungsmechanik der Organismen (Blacher et al, 1933;Liosner et al, 1936). Later on, the focus of scientific interest eventually shifted toward the regeneration of internal organs, notably parenchymal organs, in amphibians and ultimately in mammals.…”

Section: Contribution Of Russian Scientists To the Theory Of Regeneramentioning

confidence: 99%

Evolution of Regeneration in Animals: A Tangled Story

2021

View full text Add to dashboard Cite

The evolution of regenerative capacity in multicellular animals represents one of the most complex and intriguing problems in biology. How could such a seemingly advantageous trait as self-repair become consistently attenuated by the evolution? This review article examines the concept of the origin and nature of regeneration, its connection with the processes of embryonic development and asexual reproduction, as well as with the mechanisms of tissue homeostasis. The article presents a variety of classical and modern hypotheses explaining different trends in the evolution of regenerative capacity which is not always beneficial for the individual and notably for the species. Mechanistically, these trends are driven by the evolution of signaling pathways and progressive restriction of differentiation plasticity with concomitant advances in adaptive immunity. Examples of phylogenetically enhanced regenerative capacity are considered as well, with appropriate evolutionary reasoning for the enhancement and discussion of its molecular mechanisms.

show abstract

Section: Contribution Of Russian Scientists To the Theory Of Regeneramentioning

confidence: 99%

Evolution of Regeneration in Animals: A Tangled Story

2021

View full text Add to dashboard Cite

show abstract

Reconstitution of bone in regenerating forelimbs of adult Triturus viridescens

Rieck

1960

J. Exp. Zool.

View full text Add to dashboard Cite

The relation of bone to the histogenesis of cartilage in regenerating forelimbs and tails of adult Triturus viridescens

Goss

1956

Journal of Morphology

View full text Add to dashboard Cite

The organization of thcl urodele limb regenerate is characterizrd by c2 strict ~orre.jpoii~leiice, suggesting a causal relationship, betwc-c.en tlic components of the regenerate and their eonnterparts in the stump. This is most rtrikingly illustrated hy the direct contiiiuity of the old arid the new skeletal elements. lriasiiiuch a s the skeleton is the first tisbue to differentiate in a developing lhstenia, and since bone can be subjected with facility to various experimental techniques, the present account represents a n inquiry into the factors rcsponsiblc for the liistogcriesis of cartilage, with particular reference to the role of bone in this p-ocess.Notwithslanding the spatial, arid perhaps c a u d , relatioilship between corresponding skeletal elements in tlic stiinip and the regenerate, there is considerable evidence that other factors are also involved, for iiuinerous investigators have described normal skeletal regeneration f r o m limbs partially or entirely deprived of ihcir skeletal elements. Extirpation of one of the two bones in t l i c h lower extremity, followed hy amputation through the operat ed region, results in normal reconstitution of the lost parts including regeneration of the

show abstract

Regenerationspotenz der Knochenlosen Extremit�t

Cited by 5 publications

References 6 publications

Evolution of Regeneration in Animals: A Tangled Story

Evolution of Regeneration in Animals: A Tangled Story

Reconstitution of bone in regenerating forelimbs of adult Triturus viridescens

The relation of bone to the histogenesis of cartilage in regenerating forelimbs and tails of adult Triturus viridescens

Contact Info

Product

Resources

About