Reflex sympathetic dystrophy in pregnancy: nine cases and a review of the literature

Endocrine disorders in women with complex regional pain syndrome type I

“…de Mos et al (2009) did not find any association between oestrogen level and CRPS I development, though the authors noticed the decrease in CRPS I incidence during pregnancy and its increase during the first 6 months after delivery (de Mos et al, 2009). There are only a few published reports about CRPS manifestation during pregnancy, but most scientists consider pregnancy as a protective factor (Poncelet et al, 1999;Zrigui et al, 2002;Sergent et al, 2003). Tennant (2010a,b), McBeth et al (2006) and Sergent et al, (2003) pointed at the role of the hypothalamic-pituitary-adrenal and pituitary-adrenal-gonadal axes hormones (particularly cortisol) in the pathogenic mechanisms of chronic pain syndromes development.…”

Foot-ankle involvement of complex regional pain syndrome associated with pregnancy

“…CRPS is frequently seen in the third trimester of pregnancy and the involvement can be bilateral [4,8,9]. In our case, there was bilateral involvement of the ankles in the third trimester was accompanied by severe pain, edema, increased temperature, sweating, tenderness and restriction in ROM.…”

“…Hypertriglyceridaemia is a condition that can be seen in pregnancy and increases in the third trimester; in the study of Ponceleta et al [8], triglyceride levels of the patients with CRPS were found to be high and in the study conducted by Acquaviva et al [11] on 765 CRPS patient, especially the involvement of the hip joints were reported with the accompanying hypertriglyceridaemia. Additional inflammatory conditions, cellulitis, arthritis, DVT, vascular disorder, bone tumors and other malignities should be considered for the diagnosis; radiography is helpful however hence the use of radiography is limited during the pregnancy period and the condition can only be detected in 3-6 weeks after the onset, MRI is a preferable method for the diagnosis.…”

“…In a study structured with disease analysis of nine cases retrospectively and a review of the literature (57 patients and 159 sites of reflex sympathetic dystrophy) by Poncelata et al [8], it was concluded that CRPS in pregnancy was seen in different parts of the body; and the rates were as follows; 88% in hips, 25% in knees and 21% in ankles.…”

Intravenous Pamidronate for Treatment of Reflex Sympathetic Dystrophy During Breast Feeding

“…These may include pain, tenderness, increased sweating, coolness, color change (variations of pallor, cyanosis, and redness), soft tissue swelling, and patchy osteoporosis (1,2) . Reflex sympathetic dystrophy can occur in association with pregnancy (3) …”