Refinements in telemetry procedures: Seventh report of BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement, Part A

Morton, David B.; Hawkins, Penny; Bevan, R. M.; Heath, Kate; Kirkwood, James; Pearce, P.C.; Scott, Leah; Whelan, Greg; Webb, Anthony

doi:10.1258/002367703322389861

Cited by 71 publications

(79 citation statements)

References 22 publications

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“…Reuse has the potential to not only avoid the early termination of animal life, but also reduce the overall number of animals used in research, thus saving time and resources [23,24]. Also, with appropriate experimental design, reuse of animals can provide statistically powerful studies with a small number of animals [20,25,26].…”

Section: Killing Animals In Research -Is It Always Inevitable?mentioning

confidence: 99%

“…However, reusing animals raises ethical and methodological issues when compared to the use of naïve animals, which have not been subject to previous experiments and must therefore be considered on a caseby-case basis [19,24,26]. This includes defining the upper threshold of welfare impact that animals will experience as a result of cumulative experimental use, as contemplated in current EU legislation [27].…”

Section: Killing Animals In Research -Is It Always Inevitable?mentioning

confidence: 99%

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12. Killing animals as a necessary evil? The case of animal research

Franco

Olsson

2016

The End of Animal Life: A Start for Ethical Debate

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This chapter addresses the question of killing animals in research, primarily from a moral perspective, but also taking into account some of the practical and scientific considerations with moral consequences in this context. We start by exploring in which situations animals are killed in research and whether these are always inevitable, analysing re-use and re-homing of animals as potential alternatives. We then discuss for whom -and under what circumstances -killing matters, considering situations where there may be a conflict between the wish to avoid killing and that to avoid suffering, and further take humananimal interactions into account. We argue that, although there are relevant practical, scientific and ethical arguments favouring the euthanasia of animals in most research contexts, there is a potential for rehabilitating more animals than is currently the practice.

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Section: Killing Animals In Research -Is It Always Inevitable?mentioning

confidence: 99%

Section: Killing Animals In Research -Is It Always Inevitable?mentioning

confidence: 99%

12. Killing animals as a necessary evil? The case of animal research

Franco

Olsson

2016

The End of Animal Life: A Start for Ethical Debate

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“…In such cases veterinary advice on effective remedial therapy should be obtained promptly. Rarely, systemic infection and septicaemia may occur (Morton et al 2003, Hawkins et al 2004). In such cases the action taken must recognize appropriate humane endpoints to ensure that individual health and welfare is not unduly compromised, and in some instances this may mean having to euthanize the animal.…”

Section: Restraintmentioning

confidence: 99%

“…Other refinements all of which have been shown to reduce the stress induced by tethering include improving the fit of vests (Morton et al 2003, Hawkins et al 2004, improvement of the acclimatization procedure (Crockett et al 1993) and providing companions in an adjacent cage (Coelho et al 1991). has reported that juvenile rhesus macaques were successfully housed in compatible pairs while tethered.…”

Section: Restraintmentioning

confidence: 99%

“…Specific advice on refinement with regard to the administration of substances, together with a checklist of questions to consider when planning administration procedures, is set out in Morton et al (2001) and a modified version appears as Table 7. Additional questions to ask with respect to the substance administered are set out below.…”

Section: Administration Of Substances and Sampling Of Blood And Othermentioning

confidence: 99%

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Refinements in husbandry, care and common procedures for non-human primates

Jennings

Buchanan‐Smith

Gamble³

et al. 2009

Lab Anim

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Preface Whenever animals are used in research, minimizing pain and distress and promoting good welfare should be as important an objective as achieving the experimental results. This is important for humanitarian reasons, for good science, for economic reasons and in order to satisfy the broad legal principles in international legislation. It is possible to refine both husbandry and procedures to minimize suffering and improve welfare in a number of ways, and this can be greatly facilitated by ensuring that up-to-date information is readily available. The need to provide such information led the British Veterinary Association Animal Welfare Foundation (BVAAWF), the Fund for the Replacement of Animals in Medical Experiments (FRAME), the Royal Society for the Prevention of Cruelty to Animals (RSPCA) and the Universities Federation for Animal Welfare (UFAW) to establish a Joint Working Group on Refinement (JWGR) in the UK. The chair is Professor David Morton and the secretariat is provided by the RSPCA. This report is the ninth in the JWGR series. The RSPCA is opposed to the use of animals in experiments that cause pain, suffering, distress or lasting harm and together with FRAME has particular concerns about the continued use of non-human primates. The replacement of primate experiments is a primary goal for the RSPCA and FRAME. However, both organizations share with others in the Working Group, the common aim of replacing primate experiments wherever possible, reducing suffering and improving welfare while primate use continues. The reports of the refinement workshops are intended to help achieve these aims. This report produced by the British Veterinary Association Animal Welfare Foundation (BVAAWF)/Fund for the Replacement of Animals in Medical Experiments (FRAME)/Royal Society for the Prevention of Cruelty to Animals (RSPCA)/Universities Federation for Animal Welfare (UFAW) Joint Working Group on Refinement (JWGR) sets out practical guidance on refining the husbandry and care of non-human primates (hereinafter primates) and on minimizing the adverse effects of some common procedures. It provides a valuable resource to help understand the physical, social and behavioural characteristics and needs of individual primates, and is intended to develop and complement the existing literature and legislative guidelines. Topics covered include refinements in housing, husbandry and common procedures such as restraint, identification and sampling, with comprehensive advice on issues such as primate communication, assessing and facilitating primate wellbeing, establishing and maintaining social groups, environmental and nutritional enrichment and animal passports. The most commonly used species are the key focus of this resource, but its information and recommendations are generally applicable to other species, provided that relevant individual species characteristics are taken into account.

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Guidelines for the Care and Use of Laboratory Animals in Biomedical Research

Jones‐Bolin¹

2012

CP Pharmacology

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This unit provides a general overview on topics related to the practical care and use of laboratory animals in biomedical research. These topics are briefly described and provide Web sites and/or research articles that can be accessed for more detailed information. While the primary focus is on the care and use of rats and mice bred for biomedical research, many of the Web sites listed provide information on other species used for this purpose.

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Refinements in telemetry procedures: Seventh report of BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement, Part A

Cited by 71 publications

References 22 publications

12. Killing animals as a necessary evil? The case of animal research

12. Killing animals as a necessary evil? The case of animal research

Refinements in husbandry, care and common procedures for non-human primates

Guidelines for the Care and Use of Laboratory Animals in Biomedical Research

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