Reference values of mandibular condylar growth activity: a study of SUVmax with quantitative bone SPECT/CT

Lin, Zefang; Xue, Qianqian; Lin, Rui‐Biao; Yao, Shaobo; Miao, Weibing

doi:10.1097/mnm.0000000000001507

Cited by 1 publication

(1 citation statement)

References 32 publications

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“…Furthermore, Zhang et al [25] explored the value of skeletal maximum SUV obtained by SPECT/CT in the differential diagnosis of bone metastases from benign lesions. Lin et al [26] assessed the mandibular condylar growth activity with SPECT/CT to establish reference values of maximum SUV. We consider that the bone SPECT maximum SUV can be an effective tool for the characterization of jaw pathologies and normal structures in the head and neck.…”

Section: Discussionmentioning

confidence: 99%

Comparison of maximum and mean standardized uptake values of jaw pathologies with bone SPECT/CT: an especial focus on medication-related osteonecrosis of the jaw

Minami

Ogura

2022

Nuclear Medicine Communications

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Objectives To investigate the comparison of maximum and mean standardized uptake values (SUVs) of jaw pathologies with bone Single-photon emission computed tomography/computed tomography (SPECT/CT), and a special focus on medication-related osteonecrosis of the jaw (MRONJ). Methods Eighty-nine patients with jaw pathologies (63 MRONJ, 13 chronic osteomyelitis, 11 osteoradionecrosis and 2 primary intraosseous carcinoma) underwent bone SPECT/CT scans acquisition at 4 h after intravenous injection of Tc-99m hydroxymethylene diphosphonate in this prospective study. The evaluation of mean and maximum SUVs of jaw pathologies were performed using Q. Metrix and Xeleris workstation and defined the data automatically. Statistical analyses were performed by Pearson’s correlation coefficient for comparison of maximum and mean SUVs and Mann-Whitney U-test for SUVs of MRONJ. A P value lower than 0.05 was considered to indicate statistical significance. Results Maximum SUVs of MRONJ, chronic osteomyelitis, osteoradionecrosis and primary intraosseous carcinoma were 17.6 ± 8.4, 21.7 ± 7.1, 11.9 ± 4.8 and 26.6 ± 7.0, respectively. Mean SUVs of MRONJ, chronic osteomyelitis, osteoradionecrosis and primary intraosseous carcinoma were 10.1 ± 4.9, 11.9 ± 3.3, 7.0 ± 2.8 and 10.1 ± 4.5, respectively. The maximum SUV of jaw pathologies was significantly correlated with the mean SUV (Y = 0.494X + 1.228; R2 = 0.786; P < 0.001). Furthermore, maximum and mean SUVs of MRONJ had significant differences in underlying diseases, medication and staging. Conclusion The maximum and mean SUVs with bone SPECT/CT can be an effective tool for the quantitative evaluation of jaw pathologies, especially MRONJ.

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Section: Discussionmentioning

confidence: 99%