Reference Values for 7 Different Protocols of Simple Functional Tests: A Multicenter Study

Furlanetto, Karina Couto; Correia, Natielly Soares; Mesquita, Rafael; Morita, Andrea Akemi; Amaral, Daniel Pereira do; Mont’Alverne, Daniela Gardano Bucharles; Pereira, Daniel Martins; Pitta, Fábio; Corso, Simone Dal

doi:10.1016/j.apmr.2021.08.009

Cited by 23 publications

(19 citation statements)

References 45 publications

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“…Isso pode ser feito por meio da média prevista da equação (1,64 × EPE) (33) ou do percentil 10. (34) No presente estudo, o desempenho dos homens foi em média 26 degraus melhor que o das mulheres. Algumas diferenças fisiológicas entre os sexos, tais como composição corporal, função cardiovascular, função pulmonar, metabolismo de substrato e termorregulação, podem influenciar o desempenho durante o exercício.…”

Section: Discussionunclassified

Normative values and reference equation for the six-minute step test to evaluate functional exercise capacity: a multicenter study

Albuquerque1

Corso²,

Amaral

et al. 2022

J Bras Pneumol.

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Objective: To establish normative values and a reference equation for the number of steps climbed during the six-minute step test (6MST) in healthy adults, and to assess the reliability of the test and of the equation. Methods: This was a multicenter cross-sectional study involving 468 healthy volunteers (age range: 18-79 years) recruited from the general community in six research laboratories across different regions of Brazil, which is a country with continental dimensions. The 6MST was performed twice (30-min interval), and clinical, demographic, and functional variables were evaluated. An independent sample of 24 volunteers was evaluated to test the reference equation a posteriori. Results: The number of steps had excellent test-retest reliability (intraclass correlation coefficient = 0.96 [95%CI: 0.95-0.97]), and the mean number of steps was 175 ± 45, the number being 14% greater in males than in females. The best performance on the test was correlated with age (r = -0.60), sex (r = 0.28), weight (r = 0.13), height (r = 0.41), BMI (r = -0.22), waist circumference (r = -0.22), thigh circumference (r = 0.15), FVC (r = 0.54), and physical activity level (r = 0.17; p < 0.05 for all). In the regression analysis, age, sex, height, and weight explained 42% of the variability of the 6MST. Normative values were established for the 6MST according to age and sex. There was no difference between the 6MST values from the independent sample and its predicted values (157 ± 29 steps vs. 161 ± 25 steps; p = 0.47; 97% of predicted values). Conclusions: The normative values and the reference equation for the 6MST in this study seem adequate to accurately predict the physical functional performance in adults in Brazil.

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Section: Discussionunclassified

Normative values and reference equation for the six-minute step test to evaluate functional exercise capacity: a multicenter study

Albuquerque1

Corso²,

Amaral

et al. 2022

J Bras Pneumol.

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“…Multivariate analyses were performed via multiple linear regression analyses to correct for fixed covariates: sex, age, body mass index (BMI) and forced expiratory volume in 1 s (FEV 1 %pred). The fixed covariates were chosen as these are easy to assess in clinical practice and related to physical function and patient-reported outcomes [ 41 , 42 , 43 , 44 , 45 , 46 ].…”

Section: Methodsmentioning

confidence: 99%

Physical Tests Are Poorly Related to Patient-Reported Outcome Measures during Severe Acute Exacerbations of COPD

Quadflieg

Machado

Haesevoets

et al. 2021

JCM

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Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) have a negative impact on patients’ health status, including physical function and patient-reported outcomes. We aimed to explore the associations between physical tests and patient-reported outcome measures (PROMs) in hospitalised patients for an AECOPD. Patients were assessed on the day of discharge. Quadriceps force, handgrip strength, short physical performance battery (SPPB), five-repetition sit-to-stand test (5STS), four-meter gait speed test (4MGS), balance test, six-minute walk test (6MWT), COPD Assessment Test (CAT), London Chest Activity of Daily Living scale (LCADL), modified Medical Research Council (mMRC) dyspnea scale, Checklist of Individual Strength (CIS)-fatigue subscale, and Patient Health Questionnaire (PHQ-9) were collected. Sixty-nine patients with an AECOPD were included (54% female; age 69 ± 9 years; FEV1 39.2 (28.6–49.1%) predicted). Six-minute walk distance was strongly correlated with mMRC (ρ: −0.64, p < 0.0001) and moderately correlated with LCADL total score, subscales self-care and household activities (ρ ranging from −0.40 to −0.58, p < 0.01). Moreover, 4MGS was moderately correlated with mMRC (ρ: −0.49, p < 0.0001). Other correlations were weak or non-significant. During a severe AECOPD, physical tests are generally poorly related to PROMs. Therefore, a comprehensive assessment combining both physical tests and PROMs needs to be conducted in these patients to understand their health status.

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“…The timed up-and-go test (TUG) measures the time it takes an individual to stand up from an armchair, walk a distance of three metres, turn, walk back to the chair and sit down again[ 49 ]. Patients in the fourth age- and sex-specific quartile were considered to have low physical performance according to the TUG values [for both men and women (age in years), 20-29 years, 9 s; 30-39 years, 10 s; 40-39 years, 11 s; 50-59 years, 12 s. For men 60-80 years, 14 s and for women 60-80 years, 18 s] modified from Furlanetto et al [ 50 ].…”

Section: Methodsmentioning

confidence: 99%

Metabolic-associated fatty liver disease is associated with low muscle mass and strength in patients with chronic hepatitis B

Santos¹,

Brito²,

Castro³

et al. 2022

WJH

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BACKGROUND Although the prognostic relevance of sarcopenia has been increasingly recognised in the context of liver disease, there is a paucity of data evaluating body composition in patients with chronic hepatitis B (CHB). Beyond virus-related factors, nutritional and metabolic aspects can be associated with skeletal muscle abnormalities in these patients and should not be disregarded. AIM To evaluate the association between components of sarcopenia and demographic, clinical, lifestyle, nutritional, and biochemical variables in CHB patients. METHODS Dual-energy X-ray absorptiometry (DXA) was used to assess muscle mass by quantifying appendicular lean mass (ALM) adjusted for body mass index (ALM BMI ). Muscle function was evaluated by hand grip strength (HGS) and the timed up and go test. Metabolic-associated fatty liver disease (MAFLD) was defined according to the criteria proposed by an international expert panel. A body shape index and the International Physical Activity Questionnaire were used to assess central obesity and physical activity level, respectively. RESULTS This cross-sectional study included 105 CHB outpatients followed at the tertiary care ambulatory centre (mean age, 48.5 ± 12.0 years; 58.1% males; 76.2% without cirrhosis; 23.8% with compensated cirrhosis). The DXA-derived fat mass percentage was inversely correlated with the ALM BMI ( r = - 0.87) and HGS ( r = - 0.63). In the multivariable analysis, MAFLD, sedentarism and central obesity were positively and independently associated with low ALM BMI . MAFLD and central obesity were independently associated with low HGS. CONCLUSION MAFLD and central obesity were associated with low muscle mass and strength in patients with chronic hepatitis B, independent of the liver disease stage.

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Reference Values for 7 Different Protocols of Simple Functional Tests: A Multicenter Study

Cited by 23 publications

References 45 publications

Normative values and reference equation for the six-minute step test to evaluate functional exercise capacity: a multicenter study

Normative values and reference equation for the six-minute step test to evaluate functional exercise capacity: a multicenter study

Physical Tests Are Poorly Related to Patient-Reported Outcome Measures during Severe Acute Exacerbations of COPD

Metabolic-associated fatty liver disease is associated with low muscle mass and strength in patients with chronic hepatitis B

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