Reference intervals for coagulation tests in adults with different ABO blood types

Chen, Zeliang; Dai, Xiao-Qing; Cao, Jing; Tan, Xuerui; Chen, Shuying; Yu, Min

doi:10.1002/jcla.24269

Cited by 4 publications

(2 citation statements)

References 22 publications

(54 reference statements)

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“…However, the difference in APTT levels among the non-O blood types did not significantly differ. Chen et al have also found the same conclusion[ 40 ]. Although a relationship may be present between the ABO blood type and APTT, our study found that APTT did not affect the occurrence of PICC-VTE, which was similar to the results of Cardoso et al[ 41 ].…”

Section: Discussionsupporting

confidence: 64%

“…Moreover, previous studies have demonstrated that patients with non-O blood types have a higher risk of pulmonary embolism(PE) and deep venous thrombosis (DVT) [ 37 , 38 ], whereas those with the O blood type have an increased risk of bleeding[ 28 ]. Another study found that the O blood type had a higher APTT level than the non-O blood type[ 39 ]. To explore the relationship between ABO blood type and APTT levels, we compared APTT levels among the different blood types of 8477 patients in this study.…”

Section: Discussionmentioning

confidence: 99%

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The association between ABO blood types and peripherally inserted central catheter-related venous thrombosis for patients with cancer: A retrospective 7-year single-center experience and meta-analysis

Wu,

Xiao,

Tian

2024

PLoS ONE

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Background This meta-analysis evaluated the association of ABO blood type on central venous catheter-related thrombosis (CRT). Methods Data were derived from 8477 patients at Sichuan Cancer Hospital from January 2015 to December 2021 and articles previously published in Chinese and English databases. Data from our hospital were collected by reviewing electronic medical records. Searched databases included CNKI, VIP, Wan Fang, China Biomedical, PubMed, Cochrane Library, Web of Science, EMBASE, CINAHL, and OVID (up to July 2023). All statistical analyses were performed using SPSS 22.0 and Revman 5.3. The Bonferroni method was used to adjust the α test level for reducing the risk of I errors in the multiple comparisons. A P-value < 0.05 was considered statistically significant. Continuous variables were analyzed using a two-independent sample T test. The chi-squared test was used to analyze categorical data. Results A total of 818 studies were identified in the search. However, only four studies met the inclusion criteria. Combined with data from our hospital, five studies were included with a total of 18407 cases. Those studies only focused on peripherally inserted central catheter (PICC). According to the data from our hospital, logistic regression revealed that myelosuppression [odds ratio (OR), 1.473; P = 0.005) and radiotherapy(OR, 1.524; P<0.001) were independent risk factors for symptomatic PICC- VTE. Blood types A (OR, 1.404; P = 0.008), B (OR, 1.393; P = 0.016), and AB (OR, 1.861; P<0.001) were associated with a significantly higher risk of symptomatic PICC-VTE than blood type O. And the hematologic tumor has a significantly higher risk of PICC-VTE than breast cancer (OR, 0.149; P < 0.001), and gynecological tumor (OR, 0.386; P = 0.002). In the meta-analysis of the association between ABO blood type and PICC related thrombosis, the I2 statistic was not significant in any of the pairwise comparisons, and a fixed-effects model was subsequently used for all analyses. The meta-analysis indicated that the incidence of symptomatic PICC related thrombosis was significantly lower in individuals with the O blood type (3.30%) than in those with the A (4.92%), B (5.20%), or AB (6.58%) blood types (all P < 0.0083). However, in the pairwise comparisons among A, B, and AB, the differences were nonsignificant (P > 0.0083). Conclusions According to the results from our single center analysis, we found that myelosuppression, radiotherapy, hematologic tumor, and non-O blood type were independent risk factors for symptomatic PICC related thrombosis. In the meta-analysis of further exploration of ABO blood type and PICC related thrombosis, we found that ABO blood type may influence PICC related thrombosis, and individuals with the O blood type had a lower risk of PICC related thrombosis than those with non-O blood type.

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Section: Discussionsupporting

confidence: 64%

Section: Discussionmentioning

confidence: 99%

The association between ABO blood types and peripherally inserted central catheter-related venous thrombosis for patients with cancer: A retrospective 7-year single-center experience and meta-analysis

Wu,

Xiao,

Tian

2024

PLoS ONE

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Reference intervals for coagulation tests in adults with different ABO blood types

Chen

Dai

Cao

et al. 2022

Clinical Laboratory Analysis

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Introduction: Coagulation tests are affected by many factors, such as age, race, and gestation. Although coagulation test results vary by ABO blood type, reference intervals of different ABO blood groups remain to be determined. This study aims to investigate the reference ranges of coagulation tests for different ABO blood groups in the Han population in South China. Methods: A retrospective study was conducted in the First Affiliated Hospital of Shantou University Medical College. In all, 9600 individuals aged between 20 and 79 years were included. Coagulation tests, including prothrombin time (PT), international normalized ratio (INR), activated partial thromboplastin time (aPTT), thrombin time, and fibrinogen, were performed.Results: There was a significant difference in PT, INR, and aPTT among ABO blood groups. PT and INR varied slightly between ABO blood groups. There was a higher aPTT value in individuals in the O blood group than in those in non-O blood groups, in both males and females across the included age range. No differences were found in thrombin time and fibrinogen between the ABO blood groups. Conclusion:The study provides reference data on coagulation tests from ABO blood groups in South China. The established reference intervals specific to ABO blood type, sex, and age may improve clinical decisions based on coagulation tests.

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Use of hospital big data to optimize and personalize laboratory test interpretation with an application

Boutin,

Rolland,

Codet

et al. 2024

Clinica Chimica Acta

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Reference intervals for coagulation tests in adults with different ABO blood types

Cited by 4 publications

References 22 publications

The association between ABO blood types and peripherally inserted central catheter-related venous thrombosis for patients with cancer: A retrospective 7-year single-center experience and meta-analysis

The association between ABO blood types and peripherally inserted central catheter-related venous thrombosis for patients with cancer: A retrospective 7-year single-center experience and meta-analysis

Reference intervals for coagulation tests in adults with different ABO blood types

Use of hospital big data to optimize and personalize laboratory test interpretation with an application

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