Reduktion des Follikelhormons

Schwenk, Erw.; Hildebrandt, Friedrich

doi:10.1007/bf01504058

Cited by 51 publications

(4 citation statements)

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“…3. Diazo-reaction (Schwenk 8c Hildebrandt 1933). Three stabilized diazo salts of aromatic amines were used, namely a) 4-amino-2,5-dimethoxy-4'nitroazobenzene (Fast Black Salt K; Marx 8c Sobotka 1938), b) 4-amino-4'methoxy-diphenylamine (Fast Blue VB Salt; Pearl 8c McCoy 1960), and c) p-nitroaniline (Fast Red Salt GG; Pearl 8c McCoy 1960).…”

Section: B Reactions For Phenolsmentioning

confidence: 99%

Colour Reactions for the in Situ Characterisation of Steroid Oestrogens on Thin-Layer Chromatograms

Lisboa¹,

Diczfalusy²

1963

Acta Endocrinologica

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Section: B Reactions For Phenolsmentioning

confidence: 99%

Colour Reactions for the in Situ Characterisation of Steroid Oestrogens on Thin-Layer Chromatograms

Lisboa¹,

Diczfalusy²

1963

Acta Endocrinologica

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“…Dihydroguaiol (11) is oxidised by chromic mid directly to the ketone (111) and the dicarboxylic acid (VIII), also obtained on ozonisation of the benzylidene derivative of (111) . 37 The ketone (111) on treatment with niethylmagnesium iodide, dehydration, and dehydrogenation gives 1 : 4 : 7-trimethylazulene ; whereas with isopropylmagnesium iodide (111) gives the carbinol (IX), converted into 1 : 4-dimethyl-7-isopropyI(guai)az~lene.~~ The carbinol (IX), isomeric with dihydroguaiol, loses water very rapidly, showing that guaiol must have the tertiary hydroxyl group in the side chain as in (I). A sesquiterpene alcohol, shairol, which appears to be identical with guaiol, has been isolated from Ferula pyramidata by N. P. K i r ' y a l ~v .…”

Section: C02etmentioning

confidence: 99%

Organic chemistry

Baker¹,

Hey²,

Smith³

et al. 1947

Annu. Rep. Prog. Chem.

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Studies of the segregation behavior of particulate systems indicate the simultaneous occurrence of both segregation and mixing. The specific rate constants for these processes are calculated from statistical data and are shown to be a function of the particulate velocities. The results suggest the analogy of mechanical agitation in these idealized systems to thermal motion in molecular systems. Arrhenius-type plots of first-order rate constants versus the square of the reciprocal particulate velocities make possible the prediction of segregation behavior at various agitation intensities.N PREVIOUS reports (1, 2), the segregation I occurring in particulate systems of steel and glass spheres has been characterized partially.The over-all process results in a separation of particles of different physical properties and is a function of density, particle size, and the size of the container in which the segregation occurs. The present work indicates the manner in which energy input affects both the segregation and mixing processes which are shown to occur simultaneously. Donald and Roseman (3, 4), in experiments with a drum mixer, have reported that increased mixer speed reduced the final degree of mixing. The results reported here suggest that this may not always be the case, but that the segregation characteristics of granulations can be expected to vary with the physical properties of their constituents. The mechanical agitation of the systems under study shows a marked similarity to the thermal motion of molecular systems. The specific forward and reverse rate constants, representing segregation and mixing, respectively, have been evaluated from statistical data for the over-all process of segregation. These rate constants, when plotted as a function of the particulate energies, substantiate the analogy of agitation to thermal motion. THEORYSegregation has been shown to proceed by apparent over-all first-order kinetics to an equilibrium state in which the rates of mixing and unmixing balance (1). This suggests that both mixing and segregation, which are shown to occur simultaneously here at the particulate level, are first-order processes and that the observed rate constant, ko, is the sum of the constant for segregation, k1, and that for mixing, kz. The process may be considered analogous to a reversible chemicaf reaction in which both forward and reverse steps occur simultaneously. The over-all process, if followed, will reilect the predominance of one reaction step (forward or reverse) over the other. A system of particles following this behavior ( 5 ) can be represented by The concept of concentration used here relates to the relative number of spheres which may be classified as mixed or unmixed on the basis of their immediate neighbors. Thus, particles within a sample are considered unmixed in so far as they exceed their mean proportion of the total system. The remainder of particles within the sample are

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“…The female sex hormone, C18H22O2 (formula E), is a hydroxy ketone, containing an aromatic ring (A), and has therefore lost the methyl group at C-10, and the 3-hydroxy group is phenolic instead of alcoholic. Reduction of the keto group of the hormone to a secondary hydroxy group gives a dihydroxy compound, which is about six times as active as the female sex hormone (13), and which may be the cestrogenic substance actually circulating in the body. An identical dihydroxy com-pound has recently been isolated from the urine of pregnant mares (14), and from the ovaries of pigs (15).…”

Section: Cholanic Acidmentioning

confidence: 99%