Reduction of subclinical Salmonella infection in fattening pigs after dietary supplementation with a ß-galactomannan oligosaccharide

Abstract

Aims: To assess the efficacy of a b-galactomannan oligosaccharide (ß-GMOS) for the control of Salmonella infection in fattening pigs. Methods and Results: Three different doses (0Á5, 3 and 2 kg ß-GMOS per ton of feed) were used during the entire period of growing in three similar and independent field trials carried out in a small fattening unit (%100 pigs). Treatment was randomly assigned to half of the pens. Individual serum samples (20-25 per group) were collected at different times during the fattening period and a similar number of faecal samples during the fattening period and at slaughter. In addition, mesenteric lymph nodes were collected at slaughter. Herdcheck â Swine Salmonella ELISA was used for serological analyses, the ISO 6579:2002/Amd 1 : 2007 for bacteriology and the PFGE for molecular characterization of Salmonella strains. The addition of ≥2 kg t À1 of ß-GMOS to the pig diet during the entire fattening period was associated with a reduction in Salmonella prevalence, shedding and seroconversion. Conclusions: Feed supplementation with ß-GMOS may be a useful complementary tool for the control of salmonellosis in fattening pigs. Significance and Impact of the Study: ß-GMOS may be a complementary way of reducing Salmonella shedding and infection in fattening pigs.

Relationship between Salmonella infection, shedding and serology in fattening pigs in low–moderate prevalence areas

“…Herein, the presence of the pathogen not only in MLN (OR = 5.73) but also in IC (OR = 4.34) was favoured by feed with fine flour. Factors modifying the intestinal microbiota have been proposed for controlling the infection by competitive exclusion of Salmonella (Andrés‐Barranco, Vico, Grilló, & Mainar‐Jaime, ; Tanner, Chassard, Zihler Berner, & Lacroix, ). In contrast to other studies, pigs with body weight below 106 Kg had a 39.6 higher risk of infection than heavier pigs under the same level of exposure, likely related to a poor nutritional and/or health condition.…”

New innovative feeding strategy for reduction of Salmonella in swine

“…Yeast-derived 1,3-1,6beta-D-glucan and mannan-oligosaccharides which seem to be responsible for the binding of yeast products to Salmonella typhimurium indeed strongly did bind the bacterium in the adhesion assay. Mannan-oligosaccharides performed better than glucomannans or other oligosaccharides in the adhesion assay and previously proved to be effective in a field study (Andrés-Barranco et al, 2015). However, in this study, infection dose of pigs was higher and number of animals was lower, which may be the reason that the product only numerically reduced Salmonella shedding in vivo.…”

Review on the effects of potential prebiotics on controlling intestinal enteropathogens Salmonella and Escherichia coli in pig production

“…spp and pathogenic E. coli . These fermented carbohydrates can be included in diets of weaning piglets and fattening pigs at 0.2–1% for simple carbohydrate molecule (Letellier et al., ; Andrés‐Barranco et al., ) or 14–18% for fibre (Pieper et al., ,b). Mechanisms by which these prebiotics might help pigs struggling against the pathogenic invasion are changes in intestinal ecology by SCFA production, inhibition of their adherence on gut epithelium and improvement of the host's immune system gene expression regulation by mainly n ‐butyrate.…”

“…In another example, the addition of ß‐galactomannan‐oligosaccharides (ß‐GMO) to the diet was associated with a reduction in Salmonella spp. prevalence, shedding and seroconversion in fattening pigs (Andrés‐Barranco et al., ). On the other hand, fermentable fibre can shift bacterial metabolism from proteins towards carbohydrates as the main energy source and then reduce harmful protein‐derived metabolites from the protein feed.…”