Zoppi, Peracino, Marcovina and Fenili: Uric acid enzymatic determination on a centrifugal fast analyzer 59 J. Clin. Chem. Clin. Biochem. Vol. 18,1980, pp. 59-65 (Received February 12/September 17,1979) Summary: The performance of a uric acid determination kit has been evaluated for five months, under routine conditions, in a General Hospital Biochemical Laboratory.An anomalous increment in fresh serum blanks was noted in the kit when first introduced.This interference, probably due to alcohol dehydrogenase contamination, was corrected by addition of 50 mmol/1 (NH 4 ) 2 SO 4 to the reagent. Results obtained with this modified reagent correlate perfectly with those obtained with modified kits by Smith Kline Instruments (SKI), and with many other determination methods.Correlations are discussed and explanations for differences in statistical data are offered.Within run and between run precision data are presented. The kit fits perfectly with the needs of centrifugal fast analyzers and discrete micro analyzers, on account of its speed, reliability and precision.
Entwicklung und Verbesserung eines kommerziellen Testbestecks zur enzymatischen Harnsäurebestimmung an einem Zentrifugalanalysator