Reduced interhemispheric functional connectivity of children with autism spectrum disorder: evidence from functional near infrared spectroscopy studies

Zhu, Huilin; Fan, Yuebo; Guo, Huan; Huang, Dan; He, Sailing

doi:10.1364/boe.5.001262

Cited by 60 publications

(61 citation statements)

References 49 publications

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“…Since language production and comprehension rely mainly on the left hemispheric networks [26], three seeds, locating respectively at the left superior (Ch4), middle (Ch6) and inferior (Ch8) temporal gyrus, were selected for generating correlation maps. The weaker RSFC in ASD revealed here is in line with a previous fNIRS study but where less number of subjects were involved (i.e., 10 ASD + 10 TD) [10]. Bilaterally symmetric pair wise correlation values for HbO 2 and Hb were also calculated for each group and illustrated in Fig.…”

Section: Resultssupporting

confidence: 90%

“…These features make optical brain imaging very suitable to study brain function in children and other sensitive populations. A recent study using functional near infrared spectroscopy (fNIRS) in ASD showed weaker resting-state functional connectivity (RSFC) between the bilateral language areas [10]. This finding is consistent with a similar study utilizing fMRI [8].…”

Section: Introductionsupporting

confidence: 86%

“…Diagnosis of ASD relies solely on behavioral observations, e.g., via the Autism Diagnostic Observation Schedule (ADOS), the gold standard standardized ASD diagnostic measure [2,3]. Several recent imaging studies [4][5][6][7][8][9][10][11] have noted significant alteration in brain organization or function associated with ASD that may open up an avenue for imaging-based diagnostic aides in ASD.…”

Section: Introductionmentioning

confidence: 99%

“…Since both fMRI and fNIRS studies have revealed that the significant alteration in RSFC locates in the language area of the temporal lobes (TL) [8,10], in this study we use fNIRS to record and compare the spontaneous hemodynamic activity from bilateral TL on children with ASD and typically developing (TD) children. The goal of this study has two aspects: in addition to confirming weaker RSFC in ASD, we investigate potential inherent features in hemodynamic fluctuations that may be associated with ASD.…”

Section: Introductionmentioning

confidence: 99%

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Characterization of autism spectrum disorder with spontaneous hemodynamic activity

Qiu

et al. 2016

Biomed. Opt. Express

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Functional near-infrared spectroscopy (fNIRS) was used to investigate spontaneous hemodynamic activity in the temporal cortex for typically developing (TD) children and children with autism spectrum disorder (ASD). Forty-seven children participated in the experiments including twenty-five with ASD. Compared with TD children, children with ASD showed weaker bilateral resting-state functional connectivity (RSFC), but much stronger fluctuation magnitude in terms of oxy-hemoglobin (HbO 2 ) and deoxy-hemoglobin (Hb). Differentiating between ASD and TD based on a support vector machine (SVM) model including bilateral RSFC and the fluctuation power of HbO 2 and Hb as variables could achieve high accurate classification with sensitivity of 81.6% and specificity of 94.6%. This study demonstrates optical brain imaging has the potential for screening children with risk of ASD.

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Section: Resultssupporting

confidence: 90%

Section: Introductionsupporting

confidence: 86%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Characterization of autism spectrum disorder with spontaneous hemodynamic activity

Qiu

et al. 2016

Biomed. Opt. Express

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“…In order to remove the the motion artifact from our study and make sure the data were qualified for analysis and interpretation, we introduced the same training procedures as our previous studies on children with ASD [16]. During the experiment, noticeable head movement and touching the optics fibers or helmet were not allowed.…”

Section: Participants and Experimental Protocolmentioning

confidence: 99%

Atypical prefrontal cortical responses to joint/non-joint attention in children with autism spectrum disorder (ASD): A functional near-infrared spectroscopy study

Zhu

Fan

et al. 2015

Biomed. Opt. Express

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Autism spectrum disorder (ASD) is a neuro-developmental disorder, characterized by impairments in one's capacity for joint attention. In this study, functional near-infrared spectroscopy (fNIRS) was applied to study the differences in activation and functional connectivity in the prefrontal cortex between children with autism spectrum disorder (ASD) and typically developing (TD) children. 21 ASD and 20 TD children were recruited to perform joint and non-joint attention tasks. Compared with TD children, children with ASD showed reduced activation and atypical functional connectivity pattern in the prefrontal cortex during joint attention. The atypical development of left prefrontal cortex might play an important role in social cognition defects of children with ASD. ©2015 Optical Society of America

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Exploiting Thermoplasmonic Effects for Laser‐Assisted Preparation of Au Nanoparticles/InZnO Thin Film with Visible Range Photodetection Properties

Lin

Khitous

Zan

et al. 2021

Advanced Optical Materials

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To achieve such excellent electrical properties, thin-film deposition by a high-vacuum system, such as sputtering, have been widely used. [9][10][11] Such processes usually require high cost for device fabrication. In contrast, the use of solution-based materials, especially for metal precursors used in sol-gel chemistry, has attracted significant interest over the past few years. [12][13][14][15][16][17] To achieve a thin-film oxide material based on the solgel method, a high-temperature thermal annealing process is usually necessary. It is necessary to remove the organic ligands and promote the condensation reaction to obtain a metal-oxide (MO) thin film from a xerogel structure. However, high-temperature treatment may limit further applications on flexible or plastic substrates. To date, a few techniques have been reported to overcome these drawbacks. Deep ultraviolet (DUV) or near-infrared (NIR) annealing have already been proposed as the critical step for fabricating thin-film oxide semiconductor devices. Kim et al., [18] Bolat et al., [19] and Moon et al. [20] showed that DUV or NIR annealing at low environmental temperatures can be successfully used to obtain thin-film devices with good carrier mobility and electrical properties. Furthermore, we recently showed that the use of NIR dyes can significantly improve the NIR laser curing of sol-gel indium-zinc-oxide (IZO) materials and allow their use as gas sensors. [21] One of the key parameters for the laser curing of MO precursors is to generate high absorption and efficient conversion to thermal energy. Because the sol-gel layers have an intrinsic low absorption in the NIR, it is necessary to add absorbers in the thin film to generate a local temperature increase. Highly conjugated organic molecules (NIR dyes), carbon black, and carbon nanotubes are potential candidates. Gold nanoparticles (Au NPs) have also proved their utility. Under light excitation, significant thermal effects can be generated, which are known as thermoplasmonic effects. [22][23][24][25][26][27] They correspond to the damping of a plasmon resonance, which creates a temperature increase at the surface of NP that depends on several parameters such as irradiance of the incident light, irradiated area, light wavelength, nature and morphology, surface density, nature of the surrounding medium, and the substrate. [28] In specific conditions, temperature increases such as several hundreds of degrees are achievable and have been used to trigger several Here, a new method is proposed for preparing gold nanoparticles (Au NPs)/ indium-zinc-oxide (IZO) nanocomposite thin films based on photothermal mechanisms with near-Infrared (NIR) laser annealing, which allows integrating the nanomaterial on fragile substrates such as thin glass, plastic sheets, or 3D printed pieces. The Au NPs are first prepared by NIR laser dewetting of a thin Au layer. Then, the Au NPs are used to locally cure the semiconductor material and provide suitable electronic properties owing to their efficient thermoplasmonic effect...

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Reduced interhemispheric functional connectivity of children with autism spectrum disorder: evidence from functional near infrared spectroscopy studies

Cited by 60 publications

References 49 publications

Characterization of autism spectrum disorder with spontaneous hemodynamic activity

Characterization of autism spectrum disorder with spontaneous hemodynamic activity

Atypical prefrontal cortical responses to joint/non-joint attention in children with autism spectrum disorder (ASD): A functional near-infrared spectroscopy study

Exploiting Thermoplasmonic Effects for Laser‐Assisted Preparation of Au Nanoparticles/InZnO Thin Film with Visible Range Photodetection Properties

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