Reduced incidence of stress ulcer in germ-free sprague dawley rats

Prevalence of Helicobacter pylori infection in stress-induced gastric mucosal injury

“…The observed lesions that are related to H. pylori infection are probably the same as the so-called stress ulcerations. A role for H. pylori in stress ulceration was first hypothesized by ParØ et al in 1993 [19]. However, assessment of H. pylori in critically ill patients has been reported in a limited number of studies since 1996 [20,21].…”

Untitled

“…Some of these factors have been linked to H. pylori infection [ 2 , 8 ]. Animal studies show that Helicobacter infection can contribute to the pathogenesis of acute stress ulceration [ 9 , 10 ]. Robertson and colleagues showed a tentative link between H. pylori seropositivity and the severity of gastric bleeding [ 11 ].…”