Reduced cerebral glucose metabolism in asymptomatic subjects at risk for Huntington??s disease

Prevention and the Field of Mental Health: A Psychiatric Perspective

“…Some patients with Alzheimer's disease (AD) appear to have decreased brain metabolism (41). Some asymptomatic subjects at risk for Huntington's disease (HD) have been reported to show reduced glucose metabolism in the caudate area (31). In schizophrenia, prefrontal cortex dysfunction has been implicated by some imaging studies (reviewed, 37), temporal lobe dysfunction by others (R. L. Suddath, personal communica tion.)…”