Some structural members of large-scale marine vessels such as large-scale offshore structures and very large container ships are assembled by very thick plates of which thickness exceeds 60mm. Also, high-tensile steels have been selected to meet the required structural strength and fatigue strength. Generally, multi-pass welding method such as FCA(Flux-Core Arc) welding has been used to join the thick plates. Considering the welding residual stresses, fatigue strength of the welded joints of thick plates should be assured since the residual stress influences the fatigue strength. This paper presents a numerical procedure to investigate the residual stress of structure joined by multi-pass FCA welding so that it can be incorporated into the fatigue strength assessment considering the effect of welding residual stress. The residual stress distribution is also measured by X-Ray diffraction method. The residual stress obtained by the computational model also has been compared with that of experiment. The results of FEA are in very good agreement with the experimental measurements.