“…To our knowledge, no previous randomized controlled trials exist that were designed to evaluate the effect of a clinical pharmacy practice model (CPPM) on the incidence of medication errors (patient safety), and thus, most of these strategies are based on expert recommendations and descriptive studies [8,28]. In Colombia, the first and only related RCT, Effectiveness of a Method for Pharmaceutical Care in outpatients with Bipolar disorder, showed the risk of hospitalizations and emergencies was lower for the intervention group [29].…”
Background: According to WHO, medication error (ME) is a subject that requires attention at all levels of care to reduce severe and preventable damage related to medication use. Clinical pharmacy practice standards have been proposed around the world so that the pharmacist, as part of a multidisciplinary health team, can help improve patient safety; however, further evidence derived from adequate studies is needed to demonstrate this. This study aims to assess the effect of a clinical pharmacy practice model (CPPM) in preventing MEs associated with the medication use process. Methods: A prospective, stepped-wedge, cluster-randomized, controlled trial with a duration of 14 months will be performed to compare the effect of a CPPM along with the usual care process of patients in the Pablo Tobón Uribe Hospital (Medellin, Colombia). The study is designed as a cluster-randomized controlled trial, involving five hospital wards (clusters) and 720 patients. Medical wards are allocated to interventions using a stepped-wedge design. Clusters are initially assigned to the control group. After a 2-month observation period, hospital clusters were randomly allocated to the intervention group. Study outcomes will be assessed at baseline and at 2, 4, 6, 8, 10, and 12 months after randomization. The primary outcome will be to assess the effect of a CPPM on the incidence of medication errors associated with the medication use process. Drug-related problems and factors that contribute to the occurrence of MEs will be assessed as secondary outcomes. Statistical analyses will be performed using a mixed model, with the treatment group and time as fixed effects and the clustering structure as a random effect. Statistical analysis will be performed using Pearson chi-square tests and Student's t-tests, and a P value < 0.05 will be considered statistically significant.
“…To our knowledge, no previous randomized controlled trials exist that were designed to evaluate the effect of a clinical pharmacy practice model (CPPM) on the incidence of medication errors (patient safety), and thus, most of these strategies are based on expert recommendations and descriptive studies [8,28]. In Colombia, the first and only related RCT, Effectiveness of a Method for Pharmaceutical Care in outpatients with Bipolar disorder, showed the risk of hospitalizations and emergencies was lower for the intervention group [29].…”
Background: According to WHO, medication error (ME) is a subject that requires attention at all levels of care to reduce severe and preventable damage related to medication use. Clinical pharmacy practice standards have been proposed around the world so that the pharmacist, as part of a multidisciplinary health team, can help improve patient safety; however, further evidence derived from adequate studies is needed to demonstrate this. This study aims to assess the effect of a clinical pharmacy practice model (CPPM) in preventing MEs associated with the medication use process. Methods: A prospective, stepped-wedge, cluster-randomized, controlled trial with a duration of 14 months will be performed to compare the effect of a CPPM along with the usual care process of patients in the Pablo Tobón Uribe Hospital (Medellin, Colombia). The study is designed as a cluster-randomized controlled trial, involving five hospital wards (clusters) and 720 patients. Medical wards are allocated to interventions using a stepped-wedge design. Clusters are initially assigned to the control group. After a 2-month observation period, hospital clusters were randomly allocated to the intervention group. Study outcomes will be assessed at baseline and at 2, 4, 6, 8, 10, and 12 months after randomization. The primary outcome will be to assess the effect of a CPPM on the incidence of medication errors associated with the medication use process. Drug-related problems and factors that contribute to the occurrence of MEs will be assessed as secondary outcomes. Statistical analyses will be performed using a mixed model, with the treatment group and time as fixed effects and the clustering structure as a random effect. Statistical analysis will be performed using Pearson chi-square tests and Student's t-tests, and a P value < 0.05 will be considered statistically significant.
“…Both of these models promoted the participation of clinical pharmacy specialists, recognizing it as a key element in the provision of direct patient care. 29,36,37 In the case of HPTU, pharmaceutical interventions increased by 80%, classified mainly as risks that did not reach the patient (i.e., near misses). This result points to the work of pharmacists and technologists as highly preventive and important for patient safety, indirectly reducing the costs of patient care.…”
Section: Discussionmentioning
confidence: 99%
“…This model also highlighted the training of pharmacists and the importance of recording pharmaceutical interventions. Lorimer and others 37 proposed redesign of the clinical pharmacy model in a 453-bed tertiary university hospital in Canada. In their model, orientation of pharmacists toward clinical practice and relevant training allowed devotion of up to 80% of pharmacists' time to clinical activities on wards.…”
“…It has been recognized that "nurses like the model because there is only one 'go-to' pharmacist for their medication needs." 7 In addition, Lorimer and others 8 reported that the ability to speak face to face and discuss issues on the ward improved communication within the team.…”
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