Red propolis: Chemical composition and pharmacological activity

Rufatto, Luciane Corbellini; Santos, Denis Amilton dos; Marinho, Flávio; Henriques, João Antônio Pêgas; Ely, Mariana Roesch; Moura, Sidnei

doi:10.1016/j.apjtb.2017.06.009

Cited by 90 publications

(89 citation statements)

References 62 publications

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“…Red propolis is produced mainly in Brazil, Cuba, Mexico, China and Nigeria. [43] No red propolis has ever been reported in a Mediterranean or European area. Dalbergia ecastophyllum has been determined as the main source of red propolis originating in Brazil and Cuba, though the contribution of other plant species cannot be assumed.…”

Section: Color Variation Of Propolis Samplesmentioning

confidence: 99%

Photometric Analysis of Propolis from the Island of Samothraki, Greece. The Discovery of Red Propolis

Papachristoforou

Koutouvela

Menexes

et al. 2019

Chemistry & Biodiversity

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Propolis presents notable and variable antioxidant activity depending on the territory and the local flora. As a result, propolis collected from areas presenting botanical diversity can become an intriguing research field. In the present study, we examined propolis from different areas of Samothraki, a small Greek island in the north‐eastern Aegean Sea, considered a hot‐spot of plant biodiversity. The analysis of propolis samples presented huge variability in the antioxidant activity, the total polyphenol content and the total flavonoids content. Propolis from two areas presented high antioxidant activity with a maximum at 1741.48 μmol of Trolox equivalents per gram of dry propolis weight, very high polyphenol content, 378.73 mg of gallic acid equivalents per gram of dry propolis weight, and high flavonoid content with a maximum concentration of 70.31 mg of quercetin equivalents per gram of dry propolis weight. The samples that presented the best qualitative characteristics were all red propolis which is a type that has never been reported in any part of Europe.

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Section: Color Variation Of Propolis Samplesmentioning

confidence: 99%

Photometric Analysis of Propolis from the Island of Samothraki, Greece. The Discovery of Red Propolis

Papachristoforou

Koutouvela

Menexes

et al. 2019

Chemistry & Biodiversity

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“…In this sense, propolis, a resinous product produced by honey bees, is being used in the treatment of human and animal diseases (Coelho et al 2010) and has been shown to be a viable and quite promising alternative in the treatment of infections caused by S. aureus (Pinto et al 2001, Endler et al 2003, Auricchio et al 2006, Zeighampour et al 2014, Shahbaz et al 2015, Chen et al 2018) due to its proven antibacterial activity (Barbosa et al 2009, Araujo & Marcucci 2011. However the results using propolis are still conflicting (Pinto et al 2001, Loguercio et al 2006), due to its distinct and complex chemical constitution, necessitating the development of further research (Lustosa et al 2008, Rufatto et al 2017). In addition, there are few conclusive results regarding their action against MRSA, that play an important role in nosocomial infections (Taubes 2008) and a serious problem on a global scale (Astani et al 2013).…”

Section: Introductionmentioning

confidence: 99%

Chemical composition and antimicrobial activity of two extract of propolis against isolates of Staphylococcus spp. and multiresistant bacterials

et al. 2019

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Amarante J.F., Ribeiro M.F., Costa M.M., Menezes F.G., Silva T.M.S., Amarante T.A.B., Gradela A. & Moura L.M.D. 2019. Chemical composition and antimicrobial activity of two extract of propolis against isolates of Staphylococcus spp. and multiresistant bacterials. Pesquisa Veterinária Brasileira 39 (9):734-743. There is a growing need to discover and develop alternative therapies for the treatment of mastitis caused by Staphylococcus spp. and multidrug-resistant bacterial infections. This study examined the chemical composition and antimicrobial potential of two propolis extracts (EPA and EPB) against seventy-seven isolates of Staphylococcus spp. obtained from subclinical bovine mastitis; three clinical strains of MRSA and two from clinical strains of S. aureus ATCC, identified as S. aureus ATCC 6538 and S. aureus ATCC 25923. The total phenolic content was determined by the Folin-Ciocalteau method, the total flavonoid content by the Dowd method and the phenolic profile was quantified by HPLC-DAD. The MBC values of the extracts were evaluated by broth microdilution method. The amount of total phenolic and flavonoid compounds was higher in EPA than EPB. Both extracts revealed the presence of caffeic, coumaric, cinnamic, ferulic and 3,4-dihydroxybenzoic acids, with higher concentrations of coumaric and cinnamic acids. Staphylococcus spp. isolates were susceptible to EPA (90.9%), EPB (83.1%) and oxacillin (80.5%). The oxacillin susceptible isolates were also susceptible to EPA (70.1%) and EPB (80.6%), whereas those oxacillin-resistant strains were also susceptible to EPA (40.0%) and to EPB (26.7%). MBC ranged from 34.3 to 68.7μm/mL for EPA and from 68.7 to 137.5μg/mL for EPB. Both extracts inhibited significantly (100%) the clinical strains of MRSA, S. aureus ATCC 6538 and S. aureus ATCC 25923 at the concentration of 68.7μg/mL. It is concluded that both extracts of propolis, whose main constituents are coumaric and cinnamic acids, have high antimicrobial activity against the microorganisms studied, and EPA also against oxacillin-resistant strains. These findings reinforce its potential use for the treatment of bovine mastitis.

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“…If recovery after training during the competition season is not adequate, there may be elevation in the levels of pro-inflammatory markers which has serious professional and personal impacts [1,3,4] In Brazil, propolis is classified in 13 groups, based on its organoleptic and physical-chemical characteristics [5]. This material has attracted the attention of countless researchers for the effectiveness in the different pharmacological properties which can bring benefits to human health, such as antimicrobial, antioxidant and anti-inflammatory activities [6].…”

Section: Introductionmentioning

confidence: 99%

Effects of Artepelin-C Supplementation Present in Propolis Related to Inflammatory Processes in Physically Active Individuals

2019

IJFNR

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The scientific literature shows that propolis has both anti-inflammatory and antibacterial activities and is widely used in phytotherapic therapy. In this context, its main objective is to evaluate the inflammation recovery process in physically active individuals, from two groups, with or without propolis intake. Volunteers had their food, blood and pain parameters evaluated with or without propolis intake. The trial used seven male volunteers undergoing specific training in two 30day protocols, one using placebo and another using propolis which contains Artepelin-C (chemically 3,5-diprenyl-p-coumarin acid, which is one of the main phenolic acids present in the green propolis extract). Participants between 18 and 35 years old under no medication should have had at least a 6-month workout. Performance physical tests were applied, body composition measurements and blood collection were taken and a 24-hour food recall and food frequency questionnaire were carried out at São Judas Tadeu University. All volunteers were asked to register their food intake during the 30-day protocol and data were analyzed by using ANOVA and Students T-test for paired samples at <0.05 significance level set. A significant lymphocytes increase during placebo protocol and a significant reduction of these cells during propolis protocol were observed. Concerning propolis and placebo protocols, volunteers showed less pain during the former, which means that propolis is highly beneficial for those practicing intense physical exertion. Artepelin-C present in propolis protocol and having a modulator effect in inflammatory processes enables a higher intense physical exertion more easily, due to its property to minimize pain.

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Red propolis: Chemical composition and pharmacological activity

Cited by 90 publications

References 62 publications

Photometric Analysis of Propolis from the Island of Samothraki, Greece. The Discovery of Red Propolis

Photometric Analysis of Propolis from the Island of Samothraki, Greece. The Discovery of Red Propolis

Chemical composition and antimicrobial activity of two extract of propolis against isolates of Staphylococcus spp. and multiresistant bacterials

Effects of Artepelin-C Supplementation Present in Propolis Related to Inflammatory Processes in Physically Active Individuals

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