Recurrent Thyrotoxicosis after Subtotal Thyroidectomy

Ross, I. P.; Beck, J. Swanson; Donald, D.; Albert-Recht, F.; Michie, W.; Crooks, J.

doi:10.1136/bmj.4.5782.258

Cited by 34 publications

(11 citation statements)

References 16 publications

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“…A study of 141 patients after surgery indicated that in 83% iodine uptake was suppressible (Hedley et al, 1971) and this compares very well with our figure of 85% TSI negative in a group of forty postoperative patients.…”

Section: The Relationship Between Tsi and Thyroid Autonomysupporting

confidence: 76%

Thyroid Stimulators in Health and Disease*

Hall

Smith

Mukhtar

1975

Clinical Endocrinology

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Section: The Relationship Between Tsi and Thyroid Autonomysupporting

confidence: 76%

Thyroid Stimulators in Health and Disease*

Hall

Smith

Mukhtar

1975

Clinical Endocrinology

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“…For the purpose of analysis of results, a who did not have prior knowledge of preoperative TRC titre > 1/250 was regarded as being TRCtreatment until the completion of the study. From positive and an IF result of + + or + + + was the product of these measurements and the weights similarly regarded as being ACA-positive: this of the total gland and the remnant respectively, the accords with the system used previously (Hedley, total epithelial cell volume (total E), remnant epith-Ross, Beck, Donald, Albert-Recht, Michie, and elial volume (remnant E), and total glandular Crooks, 1971). colloid (total C), remnant colloid (remnant C), total glandular lymphoid tissue (total L), and rem-Results nant lymphoid tissue (remnant L) were calculated.…”

Section: Methodssupporting

confidence: 61%

“…We (Hedley et al, 1971) have suggested that this may be stimulated by release of thyroid epithelial cell antigens into the operative bed that contains dead and dying thyroid tissue and blood clot and in which organization and suture granulomas develop. It follows that the intensity of antigenic stimulation will be related to the amount of damaged thyroid epithelium exposed and hence to the volume percentage of epithelium in the gland.…”

Section: Discussionmentioning

confidence: 99%

The predictive value of histometry of thyroid tissue in anticipating hypothyroidism after subtoatl thyroidectomy for primary thyrotoxicosis.

Young¹,

Beck²,

Michie³

1975

J Clin Pathol

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48% (Beahrs and Sakulsky, 1968). Previously it has been shown that patients with low remnant weight (Michie, Pegg, and Bewsher, 1972), high preoperative antithyroid antibody titres (Irvine and Stewart, 1967), and abundant lymphoid infiltration of the thyroid (Greene, 1950;Levitt, 1951;Greene, 1953) are predisposed to the development of postoperative hypothyroidism.The present histometric study was undertaken to determine whether the structure of the glands at the time of operation bore any relation to the outcome of treatment. Materials and MethodsThis study was undertaken on 69 female primary thyrotoxic patients for whom subtotal thyroidectomy was regarded as the treatment of choice. The diagnosis of thyrotoxicosis was based on the clinical diagnostic index (Crooks, Murray, and

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“…Based on studies from the early 1970s, recurrence of thyrotoxicosis following subtotal thyroidectomies is well documented. 4 The recurrence of thyrotoxicosis following subtotal thyroidectomy may be the result of latent, persistent disease. 5 Additionally, recurrent Graves' disease may occur from thyroid tissue in ectopic and aberrant sites.…”

Section: Discussionmentioning

confidence: 99%

Recurrent thyrotoxicosis following near-total thyroidectomy

Gaschen

Cordero

Peiris

2019

Baylor University Medical Center Proceedings

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Total thyroidectomy for hyperthyroidism is usually curative. We report the unusual recurrence of thyrotoxicosis following a neartotal thyroidectomy. The patient, a 27-year-old woman, elected to have a total thyroidectomy and began levothyroxine after the procedure. Approximately 2 years later, recurrent thyrotoxicosis was evident off levothyroxine. Vascularized thyroid tissue was noted on ultrasound, and a radioactive iodine scan indicated increased uptake in the right thyroid region. She began antithyroid medication and was subsequently treated with radioactive iodine once a euthyroid state was achieved. We discuss the implications of this rare scenario-recurrence of thyrotoxicosis after near-total thyroidectomy.

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Recurrent Thyrotoxicosis after Subtotal Thyroidectomy

Cited by 34 publications

References 16 publications

Thyroid Stimulators in Health and Disease*

Thyroid Stimulators in Health and Disease*

The predictive value of histometry of thyroid tissue in anticipating hypothyroidism after subtoatl thyroidectomy for primary thyrotoxicosis.

Recurrent thyrotoxicosis following near-total thyroidectomy

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