Recurrent Takotsubo Cardiomyopathy within a Short Span of Time in a Patient with Hereditary Motor and Sensory Neuropathy

Uechi, Yoichi; Higa, Koichi

doi:10.2169/internalmedicine.47.1186

Cited by 13 publications

(7 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… 17) HSMN may also occur alongside TTS. 18) Hereditary neuropathy due to a PMP22 duplication may be associated with dilatation of the ventricles, LVHT, or heart failure ( Table 2 ). 19) …”

Section: Resultsmentioning

confidence: 99%

Heart Disease in Disorders of Muscle, Neuromuscular Transmission, and the Nerves

Finsterer

Stöllberger

2016

Korean Circ J

View full text Add to dashboard Cite

Little is known regarding cardiac involvement (CI) by neuromuscular disorders (NMDs). The purpose of this review is to summarise and discuss the major findings concerning the types, frequency, and severity of cardiac disorders in NMDs as well as their diagnosis, treatment, and overall outcome. CI in NMDs is characterized by pathologic involvement of the myocardium or cardiac conduction system. Less commonly, additional critical anatomic structures, such as the valves, coronary arteries, endocardium, pericardium, and even the aortic root may be involved. Involvement of the myocardium manifests most frequently as hypertrophic or dilated cardiomyopathy and less frequently as restrictive cardiomyopathy, non-compaction, arrhythmogenic right-ventricular dysplasia, or Takotsubo-syndrome. Cardiac conduction defects and supraventricular and ventricular arrhythmias are common cardiac manifestations of NMDs. Arrhythmias may evolve into life-threatening ventricular tachycardias, asystole, or even sudden cardiac death. CI is common and carries great prognostic significance on the outcome of dystrophinopathies, laminopathies, desminopathies, nemaline myopathy, myotonias, metabolic myopathies, Danon disease, and Barth-syndrome. The diagnosis and treatment of CI in NMDs follows established guidelines for the management of cardiac disease, but cardiotoxic medications should be avoided. CI in NMDs is relatively common and requires complete work-up following the establishment of a neurological diagnosis. Appropriate cardiac treatment significantly improves the overall long-term outcome of NMDs.

show abstract

“… 17) HSMN may also occur alongside TTS. 18) Hereditary neuropathy due to a PMP22 duplication may be associated with dilatation of the ventricles, LVHT, or heart failure ( Table 2 ). 19) …”

Section: Resultsmentioning

confidence: 99%

Heart Disease in Disorders of Muscle, Neuromuscular Transmission, and the Nerves

Finsterer

Stöllberger

2016

Korean Circ J

View full text Add to dashboard Cite

show abstract

“…Most case reports of recurrences are of typical TCM; it remains extremely rare in atypical variants [5,6,11]. Due to limited data in the literature on TCM follow up (variable lengths from a few days to 4 years) the exact incidence of recurrence is still not well established [7][8][9].…”

Section: Discussionmentioning

confidence: 99%

“…Although it is generally considered a benign phenomenon and recurrence remains rare (0-8%) [6][7][8][9], it is important to recognize its potential complications and recurrence which could have serious consequences including death [10].…”

Section: Introductionmentioning

confidence: 99%

Recurrent midventricular ballooning, a rare phenomenon

Lal

Styś

Styŝ

2012

Journal of Cardiology Cases

View full text Add to dashboard Cite

Takotsubo cardiomyopathy is characterized by transient systolic ballooning of apical or mid segments of the left ventricle (LV) mimicking acute myocardial infarction in the absence of obstructive epicardial coronary artery disease. Recurrences remain rare and most recurrence case reports are about apical ballooning or typical Takotsubo cardiomyopathy. We present a rare case of recurrence in mid ventricular ballooning or atypical variant of Takotsubo cardiomyopathy. This case highlights the importance of future follow-up and potential of recurrence even in atypical variants.

show abstract

“…Cardiomyopathy secondary to cardiotoxic chemotherapeutic agent often results in discontinuation of the offending agent and alternative treatment is explored. In the case of TC, the risk of recurrence appears to be uncommon with isolated cases being reported [26,27]. However, more recent retrospective studies suggest that the number of recurrence may be higher, 11 [28] to19% [29].…”

Section: Literature Review and Discussionmentioning

confidence: 99%

Takotsubo Cardiomyopathy Following Initial Chemotherapy Presenting with Syncope and Cardiogenic Shock – a Case Report and Literature Review

Fernandez¹,

Basra²,

Canty³

2011

J Clinic Experiment Cardiol

View full text Add to dashboard Cite

Anthracycline chemotherapeutic agents have been demonstrated to cause myocyte apoptosis leading to a dosedependent reduction in left ventricular (LV) function. There are also case reports of rapidly developing heart failure after an initial course of chemotherapy but it is uncertain as to whether the mechanism for LV dysfunction is similar. We present a case of Takotsubo cardiomyopathy (TC) developing five days after receiving the first cycle of chemotherapy consisting of rituximab, prednisone, doxorubicin, cyclophosphamide and vincristine (R-CHOP). The patient was an 85 year old woman admitted with cardiogenic shock and syncope with clinical picture suggestive of an acute coronary syndrome. Cardiac catheterization however, demonstrated no significant coronary artery disease but with unique LV apical ballooning consistent with TC. She stabilized with supportive therapy and serial echocardiograms showed normalization of LV function. She was subsequently rechallenged with R-CHOP without any deterioration in LV function. As to the best of our knowledge, this is the first reported case associating R-CHOP with TC. This case supports the concept that TC may be an idiosyncratic response to chemotherapy and our successful rechallenge with R-CHOP provides a unique insight into the feasibility of safe re-administration of chemotherapy to patients recovering from TC.

show abstract

Recurrent Takotsubo Cardiomyopathy within a Short Span of Time in a Patient with Hereditary Motor and Sensory Neuropathy

Abstract: Abstract

Cited by 13 publications

References 15 publications

Heart Disease in Disorders of Muscle, Neuromuscular Transmission, and the Nerves

Heart Disease in Disorders of Muscle, Neuromuscular Transmission, and the Nerves

Recurrent midventricular ballooning, a rare phenomenon

Takotsubo Cardiomyopathy Following Initial Chemotherapy Presenting with Syncope and Cardiogenic Shock – a Case Report and Literature Review

Contact Info

Product

Resources

About