Recurrent lower gastrointestinal bleeding due to primary colonic Kaposi's sarcoma in a patient with AIDS

Ling, Jie; Coron, Roger; Basak, Prasanta; Jesmajian, Stephen

doi:10.1177/0956462413487517

Cited by 11 publications

(9 citation statements)

References 5 publications

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“…Seldom will GI-KS precede the appearance of cutaneous lesions, but rare cases of KS isolated to the GI tract have been reported 8-11. To our knowledge, we have reported the first case of disseminated, multicentric KS without any identifiable skin involvement until the end of the patient’s life.…”

Section: Discussionmentioning

confidence: 84%

Kaposi's Sarcoma of the Rectum in a Homosexual Male with HIV-AIDS

Kumar

Nautsch

2016

ACG Case Reports Journal

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Visceral involvement in AIDS-related Kaposi’s sarcoma is common, but it is rarely seen in the absence of cutaneous disease. Most patients with gastrointestinal tract Kaposi’s sarcoma remain asymptomatic and are often diagnosed on endoscopy or autopsy. We report a case of a 24-year-old homosexual man who presented with rectal pain and bleeding and was found to have skin-sparing, disseminated Kaposi’s sarcoma with rectum, liver, lungs, and lymph node involvement. Despite treatment with highly active anti-retroviral therapy, he developed multiorgan failure resulting in death.

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Section: Discussionmentioning

confidence: 84%

Kaposi's Sarcoma of the Rectum in a Homosexual Male with HIV-AIDS

Kumar

Nautsch

2016

ACG Case Reports Journal

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“…This vascular tumour typically presents with cutaneous manifestations in the form of purple, red and brown-black plaques, macules or nodules typically found on the face, spreading to the trunk and lower abdomen 1 5–7 12 13. The incidence of skin lesions in patients with KS is typically around 90%, but this can vary with the subtype and primary tumour location 4. Rarely, this disease can present without its characteristic cutaneous involvement, making the true diagnosis difficult to ascertain.…”

Section: Discussionmentioning

confidence: 99%

Non-cutaneous AIDS-associated Kaposi’s sarcoma presenting as recurrent rectal abscesses

Schulberg

Al-Feghali

Bain³

et al. 2018

BMJ Case Reports

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Kaposi's sarcoma is a fatal disease that typically presents with cutaneous manifestations in immunocompromised individuals. There are a small number of documented cases where patients diagnosed with this disease present without cutaneous lesions. We present a 35-year-old man with recurrent rectal abscesses and fistula-in-ano, which required multiple drainage procedures. Further investigation revealed a diagnosis of HIV-AIDS, and biopsy of a rectal mass confirmed the diagnosis of visceral Kaposi's sarcoma, despite the absence of cutaneous involvement. Workup revealed hepatic metastasis and a second pulmonary primary malignancy. The patient denied chemotherapy or further intervention and was subsequently lost to follow-up. Prompt diagnosis of Kaposi's sarcoma and initiation of treatment is vital to decrease disease progression. A high index of suspicion should be present in immunocompromised patients, and clinicians must recognise atypical presentations in order to improve long-term survival.

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“…The disease is named after Moritz Kaposi, a Hungarian dermatologist on the faculty of the University of Vienna, who first described the entity in 1872 as “idiopathic multiple pigmented sarcoma of the skin” [ 3 ]. The most recurrently affected sites are the skin and mucous membrane [ 4 , 5 ], however, it can be found in other parts of the body: lungs, stomach, intestine [ 6 – 8 ], etc.…”

Section: Introductionmentioning

confidence: 99%

Primary Kaposi’s sarcoma of the nasal cavity: a case report and review of the literature

et al. 2016

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BackgroundKaposi sarcoma is a neoplastic vascular disorder. It usually present on the skin of the upper and lower extremities, rarely in the mucosa of the head and neck. The most common sites reported are within the oral cavity, particularly on the palate. Other mucosal sites are rare. We present an unusual case where the primary manifestation of the Kaposi’s sarcoma was in the nasal mucosa.Case presentationA 56-year-old female of Mediterranean descent presented with a 1 year history of swelling on the left side of her nose, nasal obstruction and occasional minor epistaxes. Physical examination showed a firm and bulging polypoid mass which filled the left nasal cavity without cutaneous lesions.Computed tomography (CT) demonstrated a tumor, measuring 77 mm in diameter, occupying the left nasal cavity causing erosion of nasal septum and extending posteriorly to the left choana and nasopharynx. There was bilateral cervical lymphadenopathy. Patient treated with chemotherapy alone. She was in a complete response after the first cycle. The patient received no further treatment. She needs a regular medical checkups that include a review of a patient’s medical history and a complete physical exam. She is in excellent local control over 12 months.ConclusionsA review of the literature revealed that only seven cases of primary Kaposi sarcoma of the nasal cavity have previously been published and only two of them presented in a patient not associated with the acquired immunodeficiency syndrome. Here, we report the third case where the primary manifestation of the Kaposi sarcoma was in the nasal cavity in a patient with an adequate immune system.

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Recurrent lower gastrointestinal bleeding due to primary colonic Kaposi's sarcoma in a patient with AIDS

Cited by 11 publications

References 5 publications

Kaposi's Sarcoma of the Rectum in a Homosexual Male with HIV-AIDS

Kaposi's Sarcoma of the Rectum in a Homosexual Male with HIV-AIDS

Non-cutaneous AIDS-associated Kaposi’s sarcoma presenting as recurrent rectal abscesses

Primary Kaposi’s sarcoma of the nasal cavity: a case report and review of the literature

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