Recurrent diffuse osteomyelitis involving the mandible

Is primary chronic osteomyelitis a uniform disease? Proposal of a classification based on a retrospective analysis of patients treated in the past 30 years

“…Several authors have pointed out a possible relationship between primary chronic osteomyelitis of the mandible and chronic recurrent multifocal osteomyelitis (Farnam et al, 1984;Suei et al, 1994Suei et al, , 1995Flygare et al, 1997;Zebedin et al, 1998;Schilling et al, 1999;Weihe et al, 2000). Suei et al (1995) concluded in a study of nine patients that diffuse sclerosing osteomyelitis is a mandibular manifestation of chronic recurrent multifocal osteomyelitis, since histopathology, clinical and radiological examinations revealed no differences.…”

Corynebacterium xerosis as a cause of vertebral osteomyelitis

“…Diphtheroid organisms have been isolated from cultures of osteomyelitis and shown to be pathogenic in these instances (1,3,9,11,12). Morrey et al (9) emphasized the importance of compromised host resistance, either local or systemic, in the pathogenesis of bone and joint infection caused by corynebacteria.…”