2019
DOI: 10.30659/odj.6.0.45-51
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Recurrent Aphthous Stomatitis Related to Psychological Stress, Food Allergy and Gerd

Abstract: Background: Recurrent Aphthous Stomatitis (RAS) is inflammation in oral mucosa characterized by recurrent single or multiple ulcers that usually affected in non keratinized mucosa. Etiology RAS is unknown but psychological stress, allergy, and gastrointestinal disease can be predisposing factors Case Management: A 23rd years old complained recurrent oral ulcer with free ulcer period for 3-5 days. The patient had a history of food allergy, GERD and psychological stress. Intraoral examination showed recurrent mu… Show more

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Cited by 7 publications
(6 citation statements)
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“…If that happens, the microorganisms that can cause SAR can develop rapidly. 16,17 The stress response causes the hypothalamus to release CRH and then release ACTH, ACTH stimulates the adrenal cortex to produce cortisol. Glucocorticoids including cortisol suppress immune functions such as IgA function.…”
Section: Discussionmentioning
confidence: 99%
“…If that happens, the microorganisms that can cause SAR can develop rapidly. 16,17 The stress response causes the hypothalamus to release CRH and then release ACTH, ACTH stimulates the adrenal cortex to produce cortisol. Glucocorticoids including cortisol suppress immune functions such as IgA function.…”
Section: Discussionmentioning
confidence: 99%
“…34 Ikatan silang antara alergen dengan reseptor pada sel mast dan basofil memicu degranulasi sehingga melepaskan mediator seperti histamin, prostaglandin, leukotrin dll, yang menimbulkan berbagai macam manifestasi klinis termasuk SAR pada rongga mulut. 35 Penelitian Sunday O dkk mendapatkan pasien yang memakai peralatan orto yang berbahan dasar nikel dapat menimbulkan SAR bersamaan dengan pemasangan dengan alat orto tersebut. 2 Ketika alat orto tersebut diganti dengan tipe bebas nikel, lesi mukosa mengalami regresi.…”
Section: Pembahasanunclassified
“…1 RAS is characterized by recurrent ulcerative lesion that is round or oval in shape, well-demarcated, covered with white to grayish-yellow pseudomembranes, and surrounded by reddish edges. 2,3 Ulcers can occur as single or multiple ulcers with three clinical characteristics, such as minor, major, and herpetiform. The etiology of RAS is still unknown, but there are several predisposing factors that are thought to trigger the onset or RAS.…”
Section: Introductionmentioning
confidence: 99%