Recurrence of Breast Carcinoma Following Immediate Reconstruction

Noone, R. Barrett; Frazier, Thomas G.; Noone, Genevieve C.; Blanchet, Nadia P.; Murphy, J. Brien; Rose, D. V.

doi:10.1097/00006534-199401000-00015

Cited by 36 publications

(50 citation statements)

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“…Research has confirmed the safety and efficacy of both neoadjuvant chemotherapy alone [7][8][9][10] and immediate reconstruction alone [1][2][3]12,[14][15][16][17][18] , but data addressing both concurrently are limited. In 1 study of 22 patients with locally advanced (stage IIB or III) cancer who received neoadjuvant chemotherapy and underwent immediate reconstruction, there was no delay in adjuvant treatment, but the perioperative morbidity rate was 14%.…”

Section: Discussionmentioning

confidence: 99%

“…Reconstruction, once was delayed for months after surgery, has proven oncologically sound and presents little additional risk of morbidity -whether autologous or prosthetic-when undertaken simultaneously with primary breast surgery. [1][2][3] By avoiding an additional procedure and achieving an immediate improvement in cosmetic result, the advantages for patients, both psychological and financial, have made immediate reconstruction a desired option for many. [4][5][6] Neoadjuvant chemotherapy also has become a critical component of modern breast cancer care.…”

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confidence: 99%

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Impact of neoadjuvant chemotherapy on breast reconstruction.

Hu¹,

Weeks²,

Chi³

et al. 2010

JCO

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Impact of neoadjuvant chemotherapy on breast reconstruction.

Hu¹,

Weeks²,

Chi³

et al. 2010

JCO

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“…Tissue transfer procedures are an oncologically safe option for breast reconstruction [7,8]. A 4-6% prevalence of skin flap or chest wall recurrences following autologous breast reconstruction using TRAM flaps has been reported [3,9] and regional nodal recurrences occur in up to 15% of patients after TRAM flap reconstruction [10,11].…”

Section: Discussionmentioning

confidence: 99%

Invasive Breast Cancer after Mastectomy and Autologous Breast Reconstruction

Zakaria

Herrick

Reynolds

et al. 2009

Scholarly Research Exchange

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Recurrence or new breast cancer after mastectomy and autologous breast reconstruction is a rare occurrence. We present a case series of four patients with this rare phenomenon and describe their presentation, workup, and surgical and adjuvant therapy. We discuss the possible physiologic mechanisms leading to tumor recurrence in a reconstructed breast along with literature review. A new palpable mass in a reconstructed breast mound warrants tissue diagnosis to avoid delay in treatment. The surgical options for breast cancer in tissue reconstructions depend on the location and extent of the tumor, involvement of the vascular pedicle, stage of disease, and adjuvant therapy options.

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“…If postmastectomy radiation is necessary (because of lymph node metastases), immediate reconstruction with implants or autologous tissue should not be performed because it may result in poor cosmetic outcomes. Published evidence indicates that immediate breast reconstruction does not adversely affect breast cancer outcome [11] . Breast reconstruction may be indicated even in disease with poor prognosis in order to improve the overall psychological rehabilitation and quality of remaining life.…”

Section: Immediate Breast Reconstructionmentioning

confidence: 99%